Plants produce a wide spectrum of secondary metabolites that play critical roles in plant-environment interactions and against biotic and abiotic stresses. Moreover, many secondary metabolites have pharmaceu- tical ef...Plants produce a wide spectrum of secondary metabolites that play critical roles in plant-environment interactions and against biotic and abiotic stresses. Moreover, many secondary metabolites have pharmaceu- tical efficacy for a wide range of diseases （cancer, malaria, etc.）. Controlled transcription of biosynthetic genes is one of the major mechanisms regulating sec- ondary metabolism in plants. Several transcription factor families such as MYC, MYB, WRKY and AP2/ERF have been found to be involved in the regulation of secondary metabolism in different medicinal plants. In addition, the biosynthesis and proper accumulation of secondary metabolites are also induced by signaling molecule jasmonic acid （JA）. This review provides an insight into JA signaling pathway and JA-mediated transcriptional regu- lation of secondary metabolism （vinblastine, nicotine, artemisinin, taxol and ginsenoside） in a range of medicinal plant species.展开更多
基金This work was supported by the National Natural Science Foundation of China （30470189, 81071821, 81250110086 and 81250110551）, the Fundamental Research for the Central University of China （721500011）, the Key Hunan Provincial Natural Science Foundation of China （13112016 and 07JJ5096）, the Science and Technology Program of Hunan Province of China （2014SK4050） and Changsha National High Tech Zone Innovation Leading Talent Program （2014-37）.
文摘Plants produce a wide spectrum of secondary metabolites that play critical roles in plant-environment interactions and against biotic and abiotic stresses. Moreover, many secondary metabolites have pharmaceu- tical efficacy for a wide range of diseases （cancer, malaria, etc.）. Controlled transcription of biosynthetic genes is one of the major mechanisms regulating sec- ondary metabolism in plants. Several transcription factor families such as MYC, MYB, WRKY and AP2/ERF have been found to be involved in the regulation of secondary metabolism in different medicinal plants. In addition, the biosynthesis and proper accumulation of secondary metabolites are also induced by signaling molecule jasmonic acid （JA）. This review provides an insight into JA signaling pathway and JA-mediated transcriptional regu- lation of secondary metabolism （vinblastine, nicotine, artemisinin, taxol and ginsenoside） in a range of medicinal plant species.
