目的观察养血生发合剂治疗斑秃和脂溢性脱发的临床疗效。方法将100例斑秃患者和100例脂溢性脱发随机各分2组,斑秃治疗组和脂溢性脱发治疗组各50例,口服养血生发合剂,30 m L/次,3次/d;斑秃对照组和脂溢性脱发对照组各50例,分别口服复方...目的观察养血生发合剂治疗斑秃和脂溢性脱发的临床疗效。方法将100例斑秃患者和100例脂溢性脱发随机各分2组,斑秃治疗组和脂溢性脱发治疗组各50例,口服养血生发合剂,30 m L/次,3次/d;斑秃对照组和脂溢性脱发对照组各50例,分别口服复方甘草酸苷和胱氨酸片、维生素B6片,3次/d。观察比较治疗组和对照组用药3个月的综合治疗效果。结果斑秃和脂溢性脱发治疗组效率分别为88.8%、74%,斑秃和脂溢性脱发对照组有效率分别为64%和56%,斑秃组和脂溢性脱发组中治疗组和对照组比较,其有效率比较均差异有统计学意义(P<0.05),说明中药治疗组治疗斑秃和脂溢性脱发的效果都比西药对照组更好,斑秃组的治疗组和脂溢性脱发的治疗组的有效率比较差异也有统计学差异(P<0.01),说明该中药制剂治疗斑秃较脂溢性脱发的疗效更优异。结论养血生发合剂治疗斑秃和脂溢性脱发疗效显著,而且对斑秃的治疗效果优于脂溢性脱发,值得推广。展开更多
Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous ...Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model for the study of plant cell elongation and cell wall biogenesis. The role of phytosterols in fiber growth was investigated by treating the fibers with tfidemorph, a sterol biosynthetic inhibitor. The inhibition of phy- tosterol biosynthesis resulted in an apparent suppression of fiber elongation in vitro or in planta. The determination of phy- tosterol quantity indicated that sitosterol and campesterol were the major phytosterols in cotton fibers; moreover, higher con- centrations of these phytosterols were observed during the period of rapid elongation of fibers. Furthermore, the decrease and increase in campesterol：sitosterol ratio was associated with the increase and decease in speed of elongation, respectively, dur- ing the elongation stage. The increase in the ratio was associated with the transition from cell elongation to secondary cell wall synthesis. In addition, a number of phytosterol biosynthetic genes were down-regulated in the short fibers of ligon lintless-1 mutant, compared to its near-isogenic wild-type TM-1. These results demonstrated that phytosterols play a crucial role in cot- ton fiber development, and particularly in fiber elongation.展开更多
文摘目的观察养血生发合剂治疗斑秃和脂溢性脱发的临床疗效。方法将100例斑秃患者和100例脂溢性脱发随机各分2组,斑秃治疗组和脂溢性脱发治疗组各50例,口服养血生发合剂,30 m L/次,3次/d;斑秃对照组和脂溢性脱发对照组各50例,分别口服复方甘草酸苷和胱氨酸片、维生素B6片,3次/d。观察比较治疗组和对照组用药3个月的综合治疗效果。结果斑秃和脂溢性脱发治疗组效率分别为88.8%、74%,斑秃和脂溢性脱发对照组有效率分别为64%和56%,斑秃组和脂溢性脱发组中治疗组和对照组比较,其有效率比较均差异有统计学意义(P<0.05),说明中药治疗组治疗斑秃和脂溢性脱发的效果都比西药对照组更好,斑秃组的治疗组和脂溢性脱发的治疗组的有效率比较差异也有统计学差异(P<0.01),说明该中药制剂治疗斑秃较脂溢性脱发的疗效更优异。结论养血生发合剂治疗斑秃和脂溢性脱发疗效显著,而且对斑秃的治疗效果优于脂溢性脱发,值得推广。
基金the National Natural Science Foundation of China (31130039, 30671258)the Genetically Modified Organisms Breeding Major Projects, China (2009ZX08009-118B)the Program for New Century Excellent Talents in University from the Ministry of Education, China (NCET-07-0712)
文摘Phytosterols play an important role in plant growth and development, including cell division, cell elongation, embryogenesis, cellulose biosynthesis, and cell wall formation. Cotton fiber, which undergoes synchronous cell elongation and a large amount of cellulose synthesis, is an ideal model for the study of plant cell elongation and cell wall biogenesis. The role of phytosterols in fiber growth was investigated by treating the fibers with tfidemorph, a sterol biosynthetic inhibitor. The inhibition of phy- tosterol biosynthesis resulted in an apparent suppression of fiber elongation in vitro or in planta. The determination of phy- tosterol quantity indicated that sitosterol and campesterol were the major phytosterols in cotton fibers; moreover, higher con- centrations of these phytosterols were observed during the period of rapid elongation of fibers. Furthermore, the decrease and increase in campesterol：sitosterol ratio was associated with the increase and decease in speed of elongation, respectively, dur- ing the elongation stage. The increase in the ratio was associated with the transition from cell elongation to secondary cell wall synthesis. In addition, a number of phytosterol biosynthetic genes were down-regulated in the short fibers of ligon lintless-1 mutant, compared to its near-isogenic wild-type TM-1. These results demonstrated that phytosterols play a crucial role in cot- ton fiber development, and particularly in fiber elongation.
