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善寻教学生发点,构建美学视野下的群文课堂——以人教版小学语文五年级下册微型小说《桥》为例 被引量:1
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作者 黄艳艳 《新课程》 2018年第25期85-85,共1页
"借助相同的议题,通过多文本的阅读,展开探索性的教学"这是群文阅读的特征。通过群文阅读来创建富有美学意义的群文课堂,这可以成为语文教学的追求。确定群文议题是进行有效群文阅读教学的重中之重,如何确定议题——寻得教学生发点,... "借助相同的议题,通过多文本的阅读,展开探索性的教学"这是群文阅读的特征。通过群文阅读来创建富有美学意义的群文课堂,这可以成为语文教学的追求。确定群文议题是进行有效群文阅读教学的重中之重,如何确定议题——寻得教学生发点,是构建美学视野下的群文课堂所要探索的第一步。 展开更多
关键词 群文阅读 群文议题 教学生发点
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如何选择童话教学的想象生发点
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作者 郭晓国 《语文世界(上旬刊)》 2022年第4期40-40,共1页
想象是童话的突出特点。统编教材童话文体单元的语文要素学习目标是“感受童话丰富的想象”。但是,学生并不清楚童话中的想象是从哪儿生发的。因此,在童话教学中,教师要抓住想象的生发点,引导学生开展想象,培养想象力。一、根据人物面... 想象是童话的突出特点。统编教材童话文体单元的语文要素学习目标是“感受童话丰富的想象”。但是,学生并不清楚童话中的想象是从哪儿生发的。因此,在童话教学中,教师要抓住想象的生发点,引导学生开展想象,培养想象力。一、根据人物面临的矛盾生发想象童话以曲折动人的故事情节吸引学生,学生喜欢童话的重要原因之一就是追求新奇的故事情节。 展开更多
关键词 统编教材 童话教学 培养想象力 生发点 曲折动人 语文 面临的矛盾 故事情节
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寻求生发点:语文课堂转型中的问题设置
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作者 吕耿銮 《语文教学与研究》 2021年第10期30-31,共2页
随着教育理念的改变,人们要求将传统的以教师为中心的教学模式转变为以学生为中心的教学模式,新课标也强调将课堂教学从“灌输中心教学”转变为“对话中心教学”。课程改革不仅是教的改革,也是学的改革,而这一过程与课堂转型息息相关。
关键词 课堂转型 课堂教学 以学生为中心的教学模式 :语文课堂 课程改革 生发点 理念的改变 新课标
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抓住三点,优化语文教学
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作者 陆亚芬 《小学教学参考(语文版)》 2015年第3期25-26,共2页
不少教师在不断地研究语文教学,努力使自己的课堂教学优质高效,但往往不得要领,主要原因是只关注课堂教学的表面,忽视本质的问题.因此,要厘清学生的学习起跑点,抓住学习的关键点,寻找语文素养的生发点,激活学生学习的内动力,然后层层展... 不少教师在不断地研究语文教学,努力使自己的课堂教学优质高效,但往往不得要领,主要原因是只关注课堂教学的表面,忽视本质的问题.因此,要厘清学生的学习起跑点,抓住学习的关键点,寻找语文素养的生发点,激活学生学习的内动力,然后层层展开教学.这样,优化语文课堂教学才成为可能. 展开更多
关键词 语文教学 起跑 关键 生发点 优化
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Development Characteristics and Control Measures for Semiothisa cineraria Bremer & Grey 被引量:1
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作者 唐浩 李军民 +2 位作者 吴家全 高华清 张松光 《Agricultural Science & Technology》 CAS 2014年第6期933-936,共4页
The development characteristics of Semiothisa cinerearia Bremer & Grey was summarized, and we also put forward the control measures of well completing insect surveys to provide scientific basis for the control and ac... The development characteristics of Semiothisa cinerearia Bremer & Grey was summarized, and we also put forward the control measures of well completing insect surveys to provide scientific basis for the control and actively carrying out comprehensive management to control the pests damage in the economic permissible level. 展开更多
关键词 Semiothisa cinerearia Bremer Grey Development characteristics Control measures
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Study on the Occurrence and Epidemic Regularity and Region Division of Rice Blast in Nanchong City 被引量:1
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作者 彭昌家 白体坤 +2 位作者 丁攀 冯礼斌 杨宇衡 《Agricultural Science & Technology》 CAS 2016年第4期927-937,共11页
With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systemati... With the aim to improve the level of monitoring and warning as well as the comprehensive control of rice blast disease, and to feasibly reduce the disease threat in Nanchong City, the methods of GPS and GIS, systematical monitoring and field survey, rice blast resistance identification, physiologic races of rice blast monitoring, and meteorological data analysis were performed to study the occurrence and epidemic region division, precise demarcation and occurrence and epidemic regularity of rice blast in Nanchong City. This study first completed the epidemic region division and precise demarcation; first clarified the initial affection(beginning period) locations, occurrence characteristics, epidemic trends and characteristics; explicated the existence of four epidemic peak periods of rice blast in the field, where the damage areas of first peak period played a decisive role during the blast epidemic years; in late May, the cumulative occurrence areas and annual occurrence areas presented higher positive correlation with the correlation coefficient of 0.817;and established a prediction model of occurrence areas per year based on the disease field rate at the end of boot stages and the diseased plant rate at dough stages. The results of investigation on the impact factors investigation of blast disease in Nanchong in recent years suggested that the internal causes were the decrease or loss of blast resistance of the rice cultivars, as well as the increase of physiological races with strong resistance to rice blast and the emergence of new virulent physiologic varieties; the external causes were suitable temperature, too much rainy, and sunlight shortage. Between 2010 and 2015, the short-term forecast accuracy for rice blast in Nanchong was up to 100%, and medium-and long-term forecast accuracy was also up to 98% and 95%, respectively, which increased by 5-15% than that before 1997, thereby making the control effect of rice blast in Nanchong increased by 15-30%. 展开更多
关键词 Rice Rice blast Region division Occurrence characteristics Epidemic regularity Early warning level
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Study on Epidemic Characteristics and Its Causes of Wheat Stripe Rust in Nanchong City 被引量:1
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作者 彭昌家 丁攀 +7 位作者 白体坤 冯礼斌 陈如胜 王婉秋 尹怀中 龙维国 肖立 文旭 《Agricultural Science & Technology》 CAS 2015年第2期292-297,共6页
On basis of the research result of stripe rust for 16 years since 1999,the epidemic characteristics and trend of stripe rust in the city were determined.Namely,the earlier the initial stage appeared,the heavier the di... On basis of the research result of stripe rust for 16 years since 1999,the epidemic characteristics and trend of stripe rust in the city were determined.Namely,the earlier the initial stage appeared,the heavier the disease would be.Furthermore,stripe rust has two introduction infection peaks,of which the first peak plays a key role.In farmlands,there are one to three epidemic peaks,and the infection area of the first peak plays the key role on the epidemic area of that year.In addition,the accumulated areas of late January was in significantly positive correlation with annually total area,with a correlation coefficient of 0.769 2.In recent 16 years,the frequency of severe stripe rust was as high as 81.25% which was 50% higher than that before 1995.The slight stripe rust became just in 2013,with a frequency of 6.3%,which indicated that the city has become a region hit by severe stripe rust.The internal reason is the reduction or loss of wheat variety's resistance to tripe rust for a new physiological race of rust is becoming pathogenic stronger and be the major race.Big fluctuation of temperatures in warm winter and spring,foggy and dew days slants much would be the external reason. 展开更多
关键词 WHEAT Stripe rust Occurrence characteristics Epidemic rule WARNING Improvement
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Reasearch on Occurrence Rules of Asian Corn Borer Ostrinia furnacalis in the Field of Waxy Corn 被引量:4
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作者 李唐 连梅力 +3 位作者 常六旺 杨俊德 张筱秀 周运宁 《Agricultural Science & Technology》 CAS 2011年第9期1388-1395,共8页
[Objective] This program aimed at providing basis for timely and effective control of Asian corn borer Ostrinia furnacalis in waxy corn fields through investigations and researching on occurrence and damage characteri... [Objective] This program aimed at providing basis for timely and effective control of Asian corn borer Ostrinia furnacalis in waxy corn fields through investigations and researching on occurrence and damage characteristics of Ostrinia furnacalis in the main producing area of waxy corn of Shanxi Province.[Method] Attraction and collection of the adults,fixed-points and random investigations on eggs and larvae were the main methods in this research.[Result] Ostrinia furnacalis appeared in two generations per year in the field of waxy corns,the generations were basically nonoverlapping with significant interval.The peak period of the overwintering generation adults in the field of waxy corn was early to middle of June,peak period of the first generation adults was from early August to late August;peak period of the first generation eggs was from the end of early June to the binning of late June,the peak period of the second generation eggs was from the middle of early August to late August.Egg-laying performances of Ostrinia furnacalis on waxy corns in different growth period suggested that the temptation of waxy corns to egg-laying of Ostrinia furnacalis had gradually increased with the continuation of growth stages before the heading of waxy corns;while after the heading of waxy corns,the temptation of waxy corns to egg-laying of Ostrinia furnacalis had gradually reduced with the continuation of growth stages.The amount of eggs on waxy corns was more than eggs on normal corns with the same growth period and growth conditions.The first generation of Ostrinia furnacalis caused more serious damages than the second generation.The first generation larvae caused more serious damages on waxy corns with early sowing period than with middle sowing period,while the late sowing fields basically uninjured.The early sowing and middle sowing corns were damaged but lightly,due to the slight occurrence of the first generation larvae.The second generation larvae caused more serious damages in late sowing waxy corn field than in middle sowing waxy corn field.As the early sowing waxy corns were harvested before the beginning of damage peak period of the second generation larvae,they were basically uninjured or slightly damaged by the second generation larvae in general years.Because the second generation larvae were in large-scale occurrence,they had caused serious damages to late and later middle sowing waxy corns.Incidence of ear rot disease on the female ears of waxy corns was closely related to the damages of Ostrinia furnacalis on ears,which was higher on the ears infested by Ostrinia furnacalis.[Conclusion] Comprehensive control on the second generation of Ostrinia furnacalis in the mid and late sowing field of waxy corn should be strengthened. 展开更多
关键词 Waxy corn Ostrinia fumacalis Occurrence rules Damage characteristics
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Comparative Study of Rice Morphogenesis with Different Cultivation Methods
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作者 严定春 《Agricultural Science & Technology》 CAS 2012年第11期2424-2428,共5页
[Objective] The aim of this study was to compare the morphological char- acteristics of rice (Oryza sativa L.) with different cultivation methods and investigate the dynamics of organ growth and development characte... [Objective] The aim of this study was to compare the morphological char- acteristics of rice (Oryza sativa L.) with different cultivation methods and investigate the dynamics of organ growth and development characteristics of different rice culti- vars. [Method] Based on continuous field observation and destructive sampling over a growing season, detailed organ morphological data were obtained including leaf length, node number, plant height, tiller number, leaf angle, leaf area and specific leaf weight, to compare organ morphological differences among 4 rice cultivars of Baidao (indica), Jinnanfeng (japonica), 9325 (japonica) and 9915 (japonica) with 3 cultivation methods of field planting in Weigang, pot planting in Weigang, and field planting in Jiangpu. [Result] Maximum leaf length of each node gradually increased at the early growth stage and decreased at the later growth stage, the relationship between maximum leaf length and node position can be described by the equations y=a,,-~ and y=ax+b; node number, growth duration, leaf length and plant height of pot planting rice in Weigang were smaller than that of the other two field planting meth- ods; the relationship between plant height and sunshine duration, plant height and GDD (growing degree days) can be described by the equation y=ax+b, 19.23 ℃.d of GDD (≥10 ≥-d) and 8.12 h of sunshine duration were required to increase 1 cm of plant height; plant height, tiller number, and leaf area of Baidao were higher than that of the other 3 laponica rice cultivars, but the specific leaf weight and leaf angle were smaller. [Conclusion] Comparison of morphological characteristic differ- ences among rice cultivars is an important way to select water-saving and drought- tolerant rice varieties. In this study, the experimental results can be integrated into a rice functional-architectural model to simulate rice organ growth dynamics in a three- dimensional space, thereby providing reference for selecting water-saving and drought-tolerant rice cultivars. 展开更多
关键词 RICE LEAF Plant height Tiller number Leaf angle
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Development Characteristics and Controlling Countermeasures of Rice Stem Borer, Chilo suppressalis(Walker) 被引量:3
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作者 唐浩 李军民 +2 位作者 吴家全 高华清 张松光 《Agricultural Science & Technology》 CAS 2014年第5期843-845,849,共4页
The development characteristics of rice stem border, Chilo suppressalis (Walker) was introduced, and the corresponding control ing measures were put forward, including agricultural control, physical control, biologi... The development characteristics of rice stem border, Chilo suppressalis (Walker) was introduced, and the corresponding control ing measures were put forward, including agricultural control, physical control, biological control, chemical control. 展开更多
关键词 RICE Development characteristics Control-ling countermeasures
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如何在童话阅读中开展想象教学
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作者 孙丽美 《语文世界(上旬刊)》 2022年第1期28-29,共2页
想象是童话文体最突出的特征之一,学生喜欢阅读童话,一个重要原因就是其中的丰富、奇特的想象能够让他们随着故事去游览奇妙的境地。在童话阅读课堂上,有的学生进不了童话的世界,有的学生甚至怕想象,还有的学生想得天花乱坠,造成这种局... 想象是童话文体最突出的特征之一,学生喜欢阅读童话,一个重要原因就是其中的丰富、奇特的想象能够让他们随着故事去游览奇妙的境地。在童话阅读课堂上,有的学生进不了童话的世界,有的学生甚至怕想象,还有的学生想得天花乱坠,造成这种局面是因为教师没有找准想象在童话中的生发点,没有打开学生想象的门窗。 展开更多
关键词 童话阅读 喜欢阅读 课堂 生发点 想象教学
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浅谈幼儿园“生活即教育”的新思考与新实践
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作者 陈和 《科学咨询》 2021年第46期148-150,共3页
“生活即教育”是陶行知生活教育理论的核心。他认为“全部课程包括全部的生活,一切课程都是生活,一切生活都是课程”,主张“把教育与生活完全融为一体。”也就是说:在我们的幼儿园一日生活中处处蕴藏着教育。因此我们在日常生活中要了... “生活即教育”是陶行知生活教育理论的核心。他认为“全部课程包括全部的生活,一切课程都是生活,一切生活都是课程”,主张“把教育与生活完全融为一体。”也就是说:在我们的幼儿园一日生活中处处蕴藏着教育。因此我们在日常生活中要了解幼儿的童真、童趣,关注他们的感受,为幼儿创设一个能使他们感到接纳、关怀、支持的良好环境,了解孩子的天性,适时地给予恰当的教育;追随孩子的兴趣,及时捕捉课程生发点;从无到有地深入开展活动,不断满足幼儿探索求知、体验表达的需要,丰富幼儿的知识,提高幼儿的能力,实现对幼儿的全面教育。 展开更多
关键词 生活即教育 陶行知生活教育理论 体验表达 幼儿园一日生活 教育与生活 良好环境 生发点
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A General Overview of the Typical 18 Frontal-VentralTransverse Cirri Oxytrichidae s. l. Genera(Ciliophora, Hypotrichia) 被引量:4
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作者 SHAO Chen LU Xiaoteng MA Honggang 《Journal of Ocean University of China》 SCIE CAS 2015年第3期522-532,共11页
Oxytrichidae s. l. ciliates usually have 18 frontal-ventral-transverse cirri which are clustered to six distinct groups usu- ally originating from six longitudinal primordia segregating 1, 3, 3, 3, 4, 4 cirri. During ... Oxytrichidae s. l. ciliates usually have 18 frontal-ventral-transverse cirri which are clustered to six distinct groups usu- ally originating from six longitudinal primordia segregating 1, 3, 3, 3, 4, 4 cirri. During morphogenesis, three dorsal kinetics anlagen are primarily formed. Fragmentation of kinety 3 usually present, while sometimes secondarily lost. Dorsomarginal kineties are formed, while sometimes lost. Oxytrichids tend to have overlapping characters, e.g. cell shape and size, infraciliature, pellicle fea- tures. This makes a great problem for genera separation. In the present work, all typical 18 frontal-ventral-transverse-cirri Oxytrichi- dae s. 1. genera were revised systematically based on their living morphology, ciliature patterns and dorsal morphogenetic features. The outline of the genera, the schematic illustrations, and the key to typical 18 frontal-ventral-transverse-cirri genera of Oxytrichidae s. l. were clarified. Additionally, some morphological and morphogenetic patterns were summarized and compared. 展开更多
关键词 Oxytrichinae Sporadotrichida Stylonychinae TAXON
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A fast direct point-by-point generating algorithm for B Spline curves and surfaces 被引量:1
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作者 李重 韩丹夫 《Journal of Zhejiang University-Science A(Applied Physics & Engineering)》 SCIE EI CAS CSCD 2005年第6期502-506,共5页
Traditional generating algorithms for B Spline curves and surfaces require approximation methods where how to increment the parameter to get the best approximation is problematic; or they take the pixel-based method n... Traditional generating algorithms for B Spline curves and surfaces require approximation methods where how to increment the parameter to get the best approximation is problematic; or they take the pixel-based method needing matrix trans- formation from B Spline representation to Bézier form. Here, a fast, direct point-by-point generating algorithm for B Spline curves and surfaces is presented. The algorithm does not need matrix transformation, can be used for uniform or nonuniform B Spline curves and surfaces of any degree, and has high generating speed and good rendering accuracy. 展开更多
关键词 Point-by-point generating algorithm B Spline curve B Spline surface Pixel
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Otolith development in larval and juvenile Schizothorax davidi: ontogeny and growth increment characteristics 被引量:1
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作者 严太明 胡佳祥 +4 位作者 蔡跃平 熊森 杨世勇 王雄延 何智 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2017年第5期1197-1204,共8页
Laboratory-reared Schizothorax davidi larvae and juveniles were examined to assess the formation and characteristics of David’s schizothoracin otoliths.Otolith development was observed and their formation period was ... Laboratory-reared Schizothorax davidi larvae and juveniles were examined to assess the formation and characteristics of David’s schizothoracin otoliths.Otolith development was observed and their formation period was verifi ed by monitoring larvae and juveniles of knownage.The results revealed that lapilli and sagittae developed before hatching,and the first otolith increment was identified at 2 days post hatching in both.The shape of lapilli was relatively stable during development compared with that of sagittae;however,growth of four sagittae and lapilli areas was consistent,but the posterior area grew faster than the anterior area and the ventral surface grew faster than the dorsal surface.Similarly,the sum length of the radius of the anterior and posterior areas on sagittae and lapilli were linearly and binomially related to total fish length,respectively.Moreover,daily deposition rates were validated by monitoring knownage larvae and juveniles.The increase in lapilli width was 1.88±0.080 0μm at the ninth increment,which reached a maximum and the decreased gradually toward the otolith edge,whereas that of sagittae increased more slowly.These results illustrate the developmental biology of S.davidi,which will aid in population conservation and fish stock management. 展开更多
关键词 OTOLITH DEVELOPMENT otolith microstructure GROWTH Schizothorax davidi
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NIS One-Temperature Dew-Point Generator Operating in the Ranae -50℃ to 0 ℃ 被引量:1
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作者 Mohamed Gamal Ahmed Doaa Abd El-Gelil +1 位作者 Essam El-Din Mahmoud Said Mazen 《Journal of Physical Science and Application》 2012年第9期335-339,共5页
This paper describes construction and characterization of a dew/frost -point generator developed at national institute for standards. It is intended to operate in the range from -50 ℃to 0 ℃. The air flows through a ... This paper describes construction and characterization of a dew/frost -point generator developed at national institute for standards. It is intended to operate in the range from -50 ℃to 0 ℃. The air flows through a saturator controlled by a regulated flow meter. The reference dew/frost -point temperature was measured by standard platinum resistance thermometer (SPRT) connected to a resistance bridge. A comparative study between the saturator temperature of the new generator measured by SPRT and the dew/frost-point temperature of a calibrated chilled-mirror hygrometer was conducted. It helped to determine the uncertainty of saturator; this uncertainty was found to be between ±0.06℃ to -4- 0.15℃ at confidence limit of 95%.Several experiments were carried out in the mentioned range. Obtained results gave the confidence that NIS generator could be used as a primary humid air generator. 展开更多
关键词 Characterization standard dew/frost point generator measurement uncertainty.
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Metabolic rate and evaporative water loss in the silky starling (Sturnus sericeus) 被引量:1
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作者 Huan-Huan BAO Qing-Jian LIANG +3 位作者 Hong-Lei ZHU Xiao-Qiu ZHOU Wei-Hong ZHENG Jin-Song LIU 《Zoological Research》 CAS CSCD 北大核心 2014年第4期280-286,共7页
To better understand the physiological characteristics of the silky starling(Sturnus sericeus), its body temperature(Tb), basal metabolic rate(BMR), evaporative water loss(EWL) and thermal conductance(C) eli... To better understand the physiological characteristics of the silky starling(Sturnus sericeus), its body temperature(Tb), basal metabolic rate(BMR), evaporative water loss(EWL) and thermal conductance(C) elicited by different ambient temperatures(Ta)(5-30 ℃) were determined in the present study. Our results showed that they have a high Tb(41.6±0.1 ℃), a wide thermal neutral zone(TNZ)(20-27.5 ℃) and a relatively low BMR within the TNZ(3.37±0.17 mL O2/g·h). The EWL was nearly stable below the TNZ(0.91±0.07 mg H2O/g·h) but increased remarkably within and above the TNZ. The C was constant below the TNZ, with a minimum value of 0.14±0.01 mL O2/g·h·℃. These findings indicate that the BMR, Tb and EWL of the silky starling were all affected by Ta, especially when Ta was below 20℃ and the EWL plays an important role in thermal regulation. 展开更多
关键词 Silky starling (Sturnus sericeus) Basal metabolic rate Body temperature Evaporative water loss
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An Inhomogeneous Distribution Model of Strong Earthquakes along Strike-Slip Act ive Fault Segments on the Chinese Continent and Its Implication in Engineering Seismology 被引量:1
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作者 ZhouBengang RanHongliu +1 位作者 SongXinchu ZhouQin 《Earthquake Research in China》 2004年第2期200-211,共12页
Through the statistical analysis of earthquake distribution along 51 strike-sli p active fault segments on the Chinese continent, we found that strong earthquak e distribution along the seismogenic fault segments is i... Through the statistical analysis of earthquake distribution along 51 strike-sli p active fault segments on the Chinese continent, we found that strong earthquak e distribution along the seismogenic fault segments is inhomogeneous and the dis tribution probability density p(K) can be stated as p(K)=1.1206e -3.947K in which K=S/(L/2), S refers to the distance from earthquake epicenter to the center of a fault segment, L is the length of the fault segment. The above model can be utilized to modify the probability density of earthquake occurrence of t he maximum magnitude interval in a potential earthquake source. Nevertheless, it is only suitable for those potential earthquake sources delineated along a sing le seismogenic fault. This inhomogeneous model has certain effects on seismic risk assessment, especia ll y for those potential earthquake sources with higher earthquake reoccurrence rat es of the maximum magnitude interval. In general, higher reoccurrence rate of th e maximum magnitude interval and lower exceeding probability level may bring lar ger difference of the results in seismic risk analysis by adopting the inhomogen eous model, the PGA values increase inner the potential earthquake source, but r educe near the vicinity and out of the potential earthquake source. Taking the T angyin potential earthquake source as an example, with exceeding probability of 10% and 2% in 50 years, the difference of the PGA values between inhomogeneous m odel and homogenous models can reach 12%. 展开更多
关键词 Strike-slip fault segment Strong earthquakes Inhomogeneous di stribution Seismic risk assessment
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Understanding the function and dysfunction of the immune system in lung cancer: the role of immune checkpoints 被引量:10
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作者 Niki Karachaliou Maria Gonzalez Cao +4 位作者 Cristina Teixidó Santiago Viteri Daniela Morales-Espinosa Mariacarmela Santarpia Rafael Rosell 《Cancer Biology & Medicine》 SCIE CAS CSCD 2015年第2期79-86,共8页
Survival rates for metastatic lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), are poor with S-year survivals of less than 5%. The immune system has an intricate and com... Survival rates for metastatic lung cancer, including non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), are poor with S-year survivals of less than 5%. The immune system has an intricate and complex relationship with tumorigenesis; a groundswell of research on the immune system is leading to greater understanding of how cancer progresses and presenting new ways to halt disease progress. Due to the extraordinary power of the immune system-- with its capacity for memory, exquisite specificity and central and universal role in human biology--immunotherapy has the potential to achieve complete, long-lasting remissions and cures, with few side effects for any cancer patient, regardless of cancer type. As a result, a range of cancer therapies are under development that work by turning our own immune cells against tumors. However deeper understanding of the complexity of immunomodulation by tumors is key to the development of effective immunotherapies, especially in lung cancer. 展开更多
关键词 Lung cancer immunotherapy immune checkpoint program death-ligand 1 (PD -L 1) program death- 1 (PD - i)
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Soil Fertility Self-development Under Ecological Restoration in the Zhuxi Watershed in the Red Soil Hilly Region of China 被引量:8
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作者 BAI Li-yue CHEN Zhi-qiang CHEN Zhi-biao 《Journal of Mountain Science》 SCIE CSCD 2014年第5期1231-1241,共11页
Current methods that utilize simple data or models to judge whether soil fertility can selfdevelop are not sufficiently rigorous. A new framework has been set up using catastrophe theory, laboratory experiment, field ... Current methods that utilize simple data or models to judge whether soil fertility can selfdevelop are not sufficiently rigorous. A new framework has been set up using catastrophe theory, laboratory experiment, field work, and 3S(Geographic information system, Global positioning system, and Remote sensing) to explore soil fertility catastrophe under ecological restoration, discriminate whether soil fertility can self-develop, and propose adjustment of ecological restoration measures in the Zhuxi watershed of Changting County, Fujian Province, China, which is a typical representative of the red soil hilly region of China. The results show that: 1) the soil fertility is obviously improved through the four ecological restoration measures, which impels soil fertility catastrophe. Among 89 soil samples, catastrophic soil samples and stable soil samples account for 26(29.21%) and 63(70.79%) of the samples, respectively. The four ecological restoration measures are listed in the order lowquality forest improvement > arbor–bush–herb mixed plantation > orchard improvement > closing measures according to the proportions of catastrophic soil samples. A typical soil sample in Bashilihe that can self-develop is selected as the criterion to judge the upper lobe and lower lobe of soil fertility in the process surface of the Cusp catastrophe model. Twenty-six(29.21%) were in the middle lobe, 10(11.24%) were in the upper lobe, and 53(70.79%) were in the lower lobe. The catastrophic direction of 26 catastrophic soil samples is to the upper lobe according to soil and water loss change as well as fieldwork. There is a significant positive correlation of Δ with soil and water loss change, and the lower soil and water loss relates to higher catastrophic probability. 2) Soil fertility self-development could be regionalized as "Soil fertility can self-develop" whose area was 12.74 km2(28.33%) distributed mainly in the leftmost and rightmost parts, "Soil fertility tends to self-develop" whose area was 11.63 km2(25.89%) distributed mainly in the middle part, and "Soil fertility cannot self-develop" whose area was 20.58 km2(45.78%) distributed mainly between the above two types. 3) There is no need to take ecological restoration measures and excessive human interference should be avoided in the future in regions of "Soil fertility can self-develop" and "Soil fertility tends to self-develop," and ecological restoration measures should be taken in region of "Soil fertility cannot self-develop." 4) We suggest withdrawal and implementation of ecological restoration measures should be incorporated into the evaluation criteria of ecological restoration to avoid misuse of funds. 展开更多
关键词 Soil fertility Catastrophe Ecological restoration Red soil hilly region
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