Objective： To investigate treatment efficacy for persistent chlamydial infection in the urogenital tract. Methods： 207 patients with persistent chlamydial urogenital infection were treated with tetracycline,azithrom...Objective： To investigate treatment efficacy for persistent chlamydial infection in the urogenital tract. Methods： 207 patients with persistent chlamydial urogenital infection were treated with tetracycline,azithromycin, ofloxacin or a combination of these.Result： 47.92%-68.60% of patients with persistent chlamydial urogenital infection were cured depending on the drug used. Ofloxacin had better results than tetracycline and azithromycin.Conclusion： Many patients were resistant to treatment with tetracycline and azithromycin. Ofloxacin proved effective.展开更多
Objective： To analyze the causes of persistent infection of Chlamydia trachomatis in the urogenital system. Method： We followed 223 patients with Chlamydia trachomatis infection who were treated regularly. Result： ...Objective： To analyze the causes of persistent infection of Chlamydia trachomatis in the urogenital system. Method： We followed 223 patients with Chlamydia trachomatis infection who were treated regularly. Result： After treatment, 22.87% of cases still tested positive. After one year and change of treatment regime,4.48% of cases remained positive, most of whom were female. Conclusion： The course of Chlamydia trachomatis infection in the urogenital system is varied. This diversity has many causes including immunocompetence the characteristics of chalmydia trchomatis infection and genetic resistance.展开更多
Objectives: To evaluate thc efficacy of nested polymerasechain reaction (PCR) with first void urine (FVU) for thediagnosis of Mycoplasma hominis in male patients. Methods: Matched FVU specimens and urethral swabs were...Objectives: To evaluate thc efficacy of nested polymerasechain reaction (PCR) with first void urine (FVU) for thediagnosis of Mycoplasma hominis in male patients. Methods: Matched FVU specimens and urethral swabs werecollected from 194 male patients with NongonococcalUrethritis and tested by nested PCR and cell culture. Cellculture was used as a gold standard for evaluating other assaytechniques. Results: For FVU nested PCR assay and FVU cell culture,our results showed that the sensitivity was 100% and 93.3%;specificity was 97.0% and 98.2%; positive predictive value(PPV) was 85.7% and 90.3%, negative predictive value (NPV)was 100% and 98.8%, respectively. The total consistencybetween the two techniques was 97.4%. Conclusions: For the diagnosis of Mycoplasma hominis inmen, nested PCR detecting FVU is a highly sensitive andspecific method. First void urine can replace swab culture orPCR in terms of acceptability and feasibility.展开更多
文摘Objective： To investigate treatment efficacy for persistent chlamydial infection in the urogenital tract. Methods： 207 patients with persistent chlamydial urogenital infection were treated with tetracycline,azithromycin, ofloxacin or a combination of these.Result： 47.92%-68.60% of patients with persistent chlamydial urogenital infection were cured depending on the drug used. Ofloxacin had better results than tetracycline and azithromycin.Conclusion： Many patients were resistant to treatment with tetracycline and azithromycin. Ofloxacin proved effective.
文摘Objective： To analyze the causes of persistent infection of Chlamydia trachomatis in the urogenital system. Method： We followed 223 patients with Chlamydia trachomatis infection who were treated regularly. Result： After treatment, 22.87% of cases still tested positive. After one year and change of treatment regime,4.48% of cases remained positive, most of whom were female. Conclusion： The course of Chlamydia trachomatis infection in the urogenital system is varied. This diversity has many causes including immunocompetence the characteristics of chalmydia trchomatis infection and genetic resistance.
文摘Objectives: To evaluate thc efficacy of nested polymerasechain reaction (PCR) with first void urine (FVU) for thediagnosis of Mycoplasma hominis in male patients. Methods: Matched FVU specimens and urethral swabs werecollected from 194 male patients with NongonococcalUrethritis and tested by nested PCR and cell culture. Cellculture was used as a gold standard for evaluating other assaytechniques. Results: For FVU nested PCR assay and FVU cell culture,our results showed that the sensitivity was 100% and 93.3%;specificity was 97.0% and 98.2%; positive predictive value(PPV) was 85.7% and 90.3%, negative predictive value (NPV)was 100% and 98.8%, respectively. The total consistencybetween the two techniques was 97.4%. Conclusions: For the diagnosis of Mycoplasma hominis inmen, nested PCR detecting FVU is a highly sensitive andspecific method. First void urine can replace swab culture orPCR in terms of acceptability and feasibility.
