Nonalcoholic fatty liver disease(NAFLD)has been recognized as a major health burden.The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity,unhealthy dietary pattern,and sedentary lifesty...Nonalcoholic fatty liver disease(NAFLD)has been recognized as a major health burden.The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity,unhealthy dietary pattern,and sedentary lifestyle.The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertain and obesity is strongly associated with hepatic steatosis;therefore,the first line of treatment is lifestyle modification.The usual management of NAFLD includes gradual weight reduction and increased physical activity(PA)leading to an improvement in serum liver enzymes,reduced hepatic fatty infiltration,and,in some cases,a reduced degree of hepatic inflammation and fibrosis.Nutrition has been demonstrated to be associated with NAFLD and Non-alcoholic steatohepatitis(NASH)in both animals and humans,and thus serves as a major route of prevention and treatment.However,most human studies are observational and retrospective,allowing limited inference about causal associations.Large prospective studies and clinical trials are now needed to establish a causal relationship.Based on available data,patients should optimally achieve a 5%-10%weight reduction.Setting realistic goals is essential for long-term successful lifestyle modification and more effort must be devoted to informing NAFLD patients of the health benefits of even a modest weight reduction.Furthermore,all NAFLD patients,whether obese or of normal weight,should be informed that a healthy diet has benefits beyond weight reduction.They should be advised to reduce saturated/trans fat and increase polyunsaturated fat,with special emphasize on omega-3 fatty acids.They should reduce added sugar to its minimum,try to avoid soft drinks containing sugar,including fruit juices that contain a lot of fructose,and increase their fiber intake.For the heavy meat eaters,especially those of red and processed meats,less meat and increased fish intake should be recommended.Minimizing fast food intake will also help maintain a healthy diet.PA should be integrated into behavioral therapy in NAFLD,as even small gains in PA and fitness may have significant health benefits.Potentially therapeutic dietary supplements are vitamin E and vitamin D,but both warrant further research.Unbalanced nutrition is not only strongly associated with NAFLD,but is also a risk factor that a large portion of the population is exposed to.Therefore,it is important to identify dietary patterns that will serve as modifiable risk factors for the prevention of NAFLD and its complications.展开更多
In the era of rapid development of the Intemet, people began to adapt to the huge growth of the Internet to facilitate people＇ s daily lives, people have been accustomed to staying at home and can easily enjoy the co...In the era of rapid development of the Intemet, people began to adapt to the huge growth of the Internet to facilitate people＇ s daily lives, people have been accustomed to staying at home and can easily enjoy the convenience and needs of life to achieve quick and easy lifestyle. The advent of the Internet age also become more virtual to business models, and now the development of enterprises has involved the application of e-commerce technology, the company＇ s business model combines network through electronic technology to some extent, and it made great adjustments and changes in order to deal with the new face of increasingly fierce competition in the market. Thus a new term： ＂E-commerce＂ is well known and accepted as more and more people. A regional economic development need of the residents＇ daily consumption is driven, so local governments need to focus on the various steady development of local small and medium enterprises. Therefore, the development of electronic commerce network technology can indirectly affect a region＇ s economic development. This paper discusses this issue.展开更多
New nomadism is a movement of global intensification that configures ways of living, inhabiting, and being in the world. The case studies of the temporary residences in Turin, in areas characterized by problems of urb...New nomadism is a movement of global intensification that configures ways of living, inhabiting, and being in the world. The case studies of the temporary residences in Turin, in areas characterized by problems of urban decay and social tensions with a high rate of immigration, are both a technical and social experimental intervention aiming, through the recovery of the existing degraded property, to transform it into a new living model of social housing, from which it will benefit not only the residents but also the entire urban area. The concept of the spaces has profoundly changed. It is no longer tied to the domestic and work sphere only, it now includes all places of associated and collective life.展开更多
Just as in the eighteenth century cotton trade pulled Palestine＇s economy into the orbit of the world economy, so it also enabled Palestine, through its ruler shaykh Zahir al-＇Umar, to instigate a process of urbaniz...Just as in the eighteenth century cotton trade pulled Palestine＇s economy into the orbit of the world economy, so it also enabled Palestine, through its ruler shaykh Zahir al-＇Umar, to instigate a process of urbanization, However, the Ottoman households that governed Galilee and Palestine＇s coastal areas did not help local merchants （tujjar） to develop inter-regional or intra-regional trade networks, as was the case in central Palestine. The disappearance of the main two obstacles to these networks--the dominant local leaders and the monopoly system--ushered in a new era in Palestine＇s trading and commercial history. Jaffa became Palestine＇s main transit port and gradually attracted wealthy merchants from far and wide. Besides their importing and exporting activities, these merchants invested heavily in citrus plantations, transforming the citrus fruit trade into Palestine＇s largest economic sector. Palestine＇s most powerful merchants played an important role as ＂the modern agents of change＂, as they did elsewhere in the Middle East. This development found expression in many aspects of their lifestyle： in the ornate architecture of their houses, in their patterns of consumption, and in their elevated living standards. These powerful merchants were also the first actors to import new technologies to Palestine, in order to develop their businesses. In short, this paper argued that the Palestinian entrepreneurial and mercantile classes, but not members of the old elite and the traditional leadership, emerged as models for imitation by society at large. In many respects, this shift in influence constituted a revolutionary change.展开更多
文摘Nonalcoholic fatty liver disease(NAFLD)has been recognized as a major health burden.The high prevalence of NAFLD is probably due to the contemporary epidemics of obesity,unhealthy dietary pattern,and sedentary lifestyle.The efficacy and safety profile of pharmacotherapy in the treatment of NAFLD remains uncertain and obesity is strongly associated with hepatic steatosis;therefore,the first line of treatment is lifestyle modification.The usual management of NAFLD includes gradual weight reduction and increased physical activity(PA)leading to an improvement in serum liver enzymes,reduced hepatic fatty infiltration,and,in some cases,a reduced degree of hepatic inflammation and fibrosis.Nutrition has been demonstrated to be associated with NAFLD and Non-alcoholic steatohepatitis(NASH)in both animals and humans,and thus serves as a major route of prevention and treatment.However,most human studies are observational and retrospective,allowing limited inference about causal associations.Large prospective studies and clinical trials are now needed to establish a causal relationship.Based on available data,patients should optimally achieve a 5%-10%weight reduction.Setting realistic goals is essential for long-term successful lifestyle modification and more effort must be devoted to informing NAFLD patients of the health benefits of even a modest weight reduction.Furthermore,all NAFLD patients,whether obese or of normal weight,should be informed that a healthy diet has benefits beyond weight reduction.They should be advised to reduce saturated/trans fat and increase polyunsaturated fat,with special emphasize on omega-3 fatty acids.They should reduce added sugar to its minimum,try to avoid soft drinks containing sugar,including fruit juices that contain a lot of fructose,and increase their fiber intake.For the heavy meat eaters,especially those of red and processed meats,less meat and increased fish intake should be recommended.Minimizing fast food intake will also help maintain a healthy diet.PA should be integrated into behavioral therapy in NAFLD,as even small gains in PA and fitness may have significant health benefits.Potentially therapeutic dietary supplements are vitamin E and vitamin D,but both warrant further research.Unbalanced nutrition is not only strongly associated with NAFLD,but is also a risk factor that a large portion of the population is exposed to.Therefore,it is important to identify dietary patterns that will serve as modifiable risk factors for the prevention of NAFLD and its complications.
文摘In the era of rapid development of the Intemet, people began to adapt to the huge growth of the Internet to facilitate people＇ s daily lives, people have been accustomed to staying at home and can easily enjoy the convenience and needs of life to achieve quick and easy lifestyle. The advent of the Internet age also become more virtual to business models, and now the development of enterprises has involved the application of e-commerce technology, the company＇ s business model combines network through electronic technology to some extent, and it made great adjustments and changes in order to deal with the new face of increasingly fierce competition in the market. Thus a new term： ＂E-commerce＂ is well known and accepted as more and more people. A regional economic development need of the residents＇ daily consumption is driven, so local governments need to focus on the various steady development of local small and medium enterprises. Therefore, the development of electronic commerce network technology can indirectly affect a region＇ s economic development. This paper discusses this issue.
文摘New nomadism is a movement of global intensification that configures ways of living, inhabiting, and being in the world. The case studies of the temporary residences in Turin, in areas characterized by problems of urban decay and social tensions with a high rate of immigration, are both a technical and social experimental intervention aiming, through the recovery of the existing degraded property, to transform it into a new living model of social housing, from which it will benefit not only the residents but also the entire urban area. The concept of the spaces has profoundly changed. It is no longer tied to the domestic and work sphere only, it now includes all places of associated and collective life.
文摘Just as in the eighteenth century cotton trade pulled Palestine＇s economy into the orbit of the world economy, so it also enabled Palestine, through its ruler shaykh Zahir al-＇Umar, to instigate a process of urbanization, However, the Ottoman households that governed Galilee and Palestine＇s coastal areas did not help local merchants （tujjar） to develop inter-regional or intra-regional trade networks, as was the case in central Palestine. The disappearance of the main two obstacles to these networks--the dominant local leaders and the monopoly system--ushered in a new era in Palestine＇s trading and commercial history. Jaffa became Palestine＇s main transit port and gradually attracted wealthy merchants from far and wide. Besides their importing and exporting activities, these merchants invested heavily in citrus plantations, transforming the citrus fruit trade into Palestine＇s largest economic sector. Palestine＇s most powerful merchants played an important role as ＂the modern agents of change＂, as they did elsewhere in the Middle East. This development found expression in many aspects of their lifestyle： in the ornate architecture of their houses, in their patterns of consumption, and in their elevated living standards. These powerful merchants were also the first actors to import new technologies to Palestine, in order to develop their businesses. In short, this paper argued that the Palestinian entrepreneurial and mercantile classes, but not members of the old elite and the traditional leadership, emerged as models for imitation by society at large. In many respects, this shift in influence constituted a revolutionary change.
