AIM. To evaluate health-related quality of life （HRQOL） in Chinese patients with chronic hepatitis C （CH-C）, and the impact of antiviral treatment. METHODS： Short Form 36 （SF-36） Health-related Quality of Life ...AIM. To evaluate health-related quality of life （HRQOL） in Chinese patients with chronic hepatitis C （CH-C）, and the impact of antiviral treatment. METHODS： Short Form 36 （SF-36） Health-related Quality of Life Questionnaires to interview CH-C patients, and age- and sex-matched control subjects at outpatient clinics of a medical center in Taiwan were used. Data were transformed to scores for comparisons of eight major SF-36 domains. We also enrolled consecutive CH-C patients who completed one course of antiviral treatment （interferon α with ribavirin）, and measured the HRQOL before, at the 12m wk of treatment, at the end of treatment, and at mo 6, after stopping the treatment to evaluate the impact of antiviral treatment. RESULTS： A total of 371 outpatients were enrolled, including 182 with CH-C and 189 age- and sex-matched subjects without CH-C. CH-C subjects had obviously lower educational status （P〈0.01）. Mean scores of domains in general health, physical functioning, role-physical, role-emotional, vitality, and mental health of the SF-36 were significantly lower in subjects with CH-C than those without CH-C （P〈0.05）. In an analysis of 47 CH-C patients who received and completed the whole course of antiviral treatment, mean scores of all domains were significantly lower at wk 12 of treatment compared to baseline. The scores returned to pretreatment values by the end of treatment, but were significantly increased at mo 6 after stopping the treatment. Among the 47 CH-C patients, 21 had sustained responses and 26 had nonsustained responses to antiviral treatment. Compared to pretreatment values, subjects with sustained responses had significantly lower social functioning scores at wk 12 of treatment, and scores for all SF-36 domains returned to pretreatment values, and increased significantly at mo 6 after stopping the treatment. For non-sustained virological responders, scores of all SF-36 domains significantly decreased at wk 12 of treatment, and did not increase significantly by the end of treatment, or at mo 6 after stopping the treatment when compared to the pretreatment values. CONCLUSION： HRQOL in CH-C patients is significantly impaired in most SF-36 domains. Antiviral treatment impaired HRQOL of CH-C subjects during early treatment, mainly in non-sustained virological responders, and improved at mo 6 after stopping the treatment, mainly in sustained virological responders.展开更多
In more recent times, health-related quality of life (HRQOL) measurements have formed an important part of as- sessing the quality of routine care in general practice. For a measure to have clinical usefulness it must...In more recent times, health-related quality of life (HRQOL) measurements have formed an important part of as- sessing the quality of routine care in general practice. For a measure to have clinical usefulness it must not only be valid, appro- priate, reliable, responsive, and capable of being interpreted, but it must also be simple, fast to complete, easy to score, and provide useful clinical data. The Two-step method of choosing appropriate measures is introduced. Then through comparison of generic instruments with disease-specific instruments, we can conclude that sometimes a combination of generic and disease-specific HRQOL measures may be more appropriate for monitoring changes in a patient’s health status due to an intervention.展开更多
In the last two or three decades,physical activity(PA) has gained increasing recognition as being essential for maintaining good health and improving quality of life for all ages.Children have traditionally been activ...In the last two or three decades,physical activity(PA) has gained increasing recognition as being essential for maintaining good health and improving quality of life for all ages.Children have traditionally been active in both free play and organized sports.However,there has been a recent decline in the PA levels among children for various reasons.This lifestyle change has resulted in increased obesity accompanied by a rise in diabetes and cardiovascular risk among otherwise healthy children.These lifestyle changes have been shown to be even more a problem when the child is already affected by a chronic disease.Due to medical limitations and contraindications,much care must be taken to make certain that these children are involved in the appropriate volume and intensity of exercise.The type of activity must also be given careful consideration to avoid undue risk for the child who may have problems such as poor balance,limited strength,poor vision,or cognitive disability.Further complications are either caused or exacerbated by lack of sufficient PA.The priority beyond concern for safety should be focused on ensuring the highest quality of life possible.The purpose of this review is to examine how PA can benefit children with selected chronic health conditions.展开更多
We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living...We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living corporeality） within the framework of Enrique Dussel＇s Latin American Political Philosophy. We are interested in these theoretical approaches （Foucault＇s biopolitics and Dussel＇s Liberation Politics） given the political implications and prominence they grant to the notions of body and life in contemporary societies. The works we are interested in to contrast present different standpoints： In the first one, life is related to the exercise of political power, whereas in the second one its approach concentrates on political emancipation processes. We believe, however, that it is possible to find convergence points between them that allow us to explain, to a certain extent, the importance of the notion of life in contemporary societies. For this purpose, we will carry out an analysis of the notion of ＂counter behaviors,＂ a concept that Foucault briefly develops to explain how life has not been thoroughly integrated to technologies that dominate or run it but instead escape them ceaselessly.展开更多
With the nervousness degree of people＇s life pace accelerating and the increasing of work task, human health is increasingly being ignored. In order to improve the national physical health, the state advocates to sta...With the nervousness degree of people＇s life pace accelerating and the increasing of work task, human health is increasingly being ignored. In order to improve the national physical health, the state advocates to start national fitness activities. Under this background, each region begins to carry out the construction of the sport ground and conducts fruitful activities. Based on this, the paper has carried out the analysis and research on the construction and operation conditions of the sport ground under the national fitness background.展开更多
Physical education is an important part of campus culture of the body, it has become one of the main ways for modem college students to relax, and it has a positive impact on construction of campus culture. So attenti...Physical education is an important part of campus culture of the body, it has become one of the main ways for modem college students to relax, and it has a positive impact on construction of campus culture. So attention to sports participation of college students and promoting college students actively to join in sports activities has become an important part of the construction of campus culture. Universities undertake the mission to train highly qualified personnel, it should guide students to participate in various forms of physical activity related to local conditions, and we establish certain style and taste of the campus culture. This paper aims to identify the impact of college students＇ physical conditions to construction of campus culture, so as to develop and improve the main sports participation consciousness of students in sport, we hope that we can comprehensively improve the quality of university education for better college students sports activities and to create a harmonious, strong campus culture.展开更多
基金Supported by the National Science Council, Taiwan, China, NSC 89-2314-B-010-475
文摘AIM. To evaluate health-related quality of life （HRQOL） in Chinese patients with chronic hepatitis C （CH-C）, and the impact of antiviral treatment. METHODS： Short Form 36 （SF-36） Health-related Quality of Life Questionnaires to interview CH-C patients, and age- and sex-matched control subjects at outpatient clinics of a medical center in Taiwan were used. Data were transformed to scores for comparisons of eight major SF-36 domains. We also enrolled consecutive CH-C patients who completed one course of antiviral treatment （interferon α with ribavirin）, and measured the HRQOL before, at the 12m wk of treatment, at the end of treatment, and at mo 6, after stopping the treatment to evaluate the impact of antiviral treatment. RESULTS： A total of 371 outpatients were enrolled, including 182 with CH-C and 189 age- and sex-matched subjects without CH-C. CH-C subjects had obviously lower educational status （P〈0.01）. Mean scores of domains in general health, physical functioning, role-physical, role-emotional, vitality, and mental health of the SF-36 were significantly lower in subjects with CH-C than those without CH-C （P〈0.05）. In an analysis of 47 CH-C patients who received and completed the whole course of antiviral treatment, mean scores of all domains were significantly lower at wk 12 of treatment compared to baseline. The scores returned to pretreatment values by the end of treatment, but were significantly increased at mo 6 after stopping the treatment. Among the 47 CH-C patients, 21 had sustained responses and 26 had nonsustained responses to antiviral treatment. Compared to pretreatment values, subjects with sustained responses had significantly lower social functioning scores at wk 12 of treatment, and scores for all SF-36 domains returned to pretreatment values, and increased significantly at mo 6 after stopping the treatment. For non-sustained virological responders, scores of all SF-36 domains significantly decreased at wk 12 of treatment, and did not increase significantly by the end of treatment, or at mo 6 after stopping the treatment when compared to the pretreatment values. CONCLUSION： HRQOL in CH-C patients is significantly impaired in most SF-36 domains. Antiviral treatment impaired HRQOL of CH-C subjects during early treatment, mainly in non-sustained virological responders, and improved at mo 6 after stopping the treatment, mainly in sustained virological responders.
文摘In more recent times, health-related quality of life (HRQOL) measurements have formed an important part of as- sessing the quality of routine care in general practice. For a measure to have clinical usefulness it must not only be valid, appro- priate, reliable, responsive, and capable of being interpreted, but it must also be simple, fast to complete, easy to score, and provide useful clinical data. The Two-step method of choosing appropriate measures is introduced. Then through comparison of generic instruments with disease-specific instruments, we can conclude that sometimes a combination of generic and disease-specific HRQOL measures may be more appropriate for monitoring changes in a patient’s health status due to an intervention.
文摘In the last two or three decades,physical activity(PA) has gained increasing recognition as being essential for maintaining good health and improving quality of life for all ages.Children have traditionally been active in both free play and organized sports.However,there has been a recent decline in the PA levels among children for various reasons.This lifestyle change has resulted in increased obesity accompanied by a rise in diabetes and cardiovascular risk among otherwise healthy children.These lifestyle changes have been shown to be even more a problem when the child is already affected by a chronic disease.Due to medical limitations and contraindications,much care must be taken to make certain that these children are involved in the appropriate volume and intensity of exercise.The type of activity must also be given careful consideration to avoid undue risk for the child who may have problems such as poor balance,limited strength,poor vision,or cognitive disability.Further complications are either caused or exacerbated by lack of sufficient PA.The priority beyond concern for safety should be focused on ensuring the highest quality of life possible.The purpose of this review is to examine how PA can benefit children with selected chronic health conditions.
文摘We intend to get a close look at Foucault＇s work on biopolitics with the aim of contrasting some of its aspects with the developments linked to the emancipatory and liberating potential of the notion of life （living corporeality） within the framework of Enrique Dussel＇s Latin American Political Philosophy. We are interested in these theoretical approaches （Foucault＇s biopolitics and Dussel＇s Liberation Politics） given the political implications and prominence they grant to the notions of body and life in contemporary societies. The works we are interested in to contrast present different standpoints： In the first one, life is related to the exercise of political power, whereas in the second one its approach concentrates on political emancipation processes. We believe, however, that it is possible to find convergence points between them that allow us to explain, to a certain extent, the importance of the notion of life in contemporary societies. For this purpose, we will carry out an analysis of the notion of ＂counter behaviors,＂ a concept that Foucault briefly develops to explain how life has not been thoroughly integrated to technologies that dominate or run it but instead escape them ceaselessly.
文摘With the nervousness degree of people＇s life pace accelerating and the increasing of work task, human health is increasingly being ignored. In order to improve the national physical health, the state advocates to start national fitness activities. Under this background, each region begins to carry out the construction of the sport ground and conducts fruitful activities. Based on this, the paper has carried out the analysis and research on the construction and operation conditions of the sport ground under the national fitness background.
文摘Physical education is an important part of campus culture of the body, it has become one of the main ways for modem college students to relax, and it has a positive impact on construction of campus culture. So attention to sports participation of college students and promoting college students actively to join in sports activities has become an important part of the construction of campus culture. Universities undertake the mission to train highly qualified personnel, it should guide students to participate in various forms of physical activity related to local conditions, and we establish certain style and taste of the campus culture. This paper aims to identify the impact of college students＇ physical conditions to construction of campus culture, so as to develop and improve the main sports participation consciousness of students in sport, we hope that we can comprehensively improve the quality of university education for better college students sports activities and to create a harmonious, strong campus culture.
