To study the alternating current （AC） impedance properties of Ag/AgC1 electrocardiograph （ECG） electrodes, the electrode pair was gel-to-gel connected, and then the electrical potential was recorded after a safe s...To study the alternating current （AC） impedance properties of Ag/AgC1 electrocardiograph （ECG） electrodes, the electrode pair was gel-to-gel connected, and then the electrical potential was recorded after a safe stimulating current passes through the electrode pair, so the AC impedance data of ECG electrodes were obtained. Varying the frequency and value of stimulating current, the detailed comparison and analysis of AC impedance properties of the electrodes were performed, and the stability was further characterized by using the continuous measurement within 24 h. The experimental results show that the AC impedance values of electrodes decreased, and then slightly increased with the increase of frequency of stimulating current. The minimum AC impedance value was obtained when the frequency was changed to 10 kHz. When the stimulating current increased, the AC impedance values of electrodes showed a slight decrease, but did not change significantly. Besides, the continuous measurement results show that the impedance value presented a significant increase in the initial 30 min, and then was stabilized in the following measuring process.展开更多
The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens...The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens, which is a straight-forward way for targeted analysis. However, there are still limitations during the practical applications due to the big size of the antibodies, which accelerate the discovery of small molecular probes. Peptides built from various optional building blocks and easily achieved by chemical synthetic approaches with predictable conformations, are versatile and can act as tailor-made targeting vehicles.In this mini review, we summarize the recent developments in the discovery of novel peptides for bioanalytical and biomedical applications. Progresses in peptide-library design and selection strategies are presented. Recent achievements in the peptide-guided detection, imaging and disease treatment are also focused.展开更多
OBJECTIVE: To explore the concept and norm of fracture healing with osteopathy in traditional Mongolian medicine (TMM). METHODS: Based on the correspondence between man and the universe (including psychosomatic integr...OBJECTIVE: To explore the concept and norm of fracture healing with osteopathy in traditional Mongolian medicine (TMM). METHODS: Based on the correspondence between man and the universe (including psychosomatic integration) in fracture healing with osteopathy in TMM, we used modern physio-psychological and biomechanical principles and methods to probe the integrated, dynamic and functional characteristics of fracture healing. RESULTS: Based on the integration of limbs and the body, unification of the body and function and harmony of man and nature (including psychoso-matic integration), fracture healing with osteopathy in TMM comprises the concept of natural functional healing of fractures, and follows the norm of considering physiological healing and psychological function as well as limb healing and motor function. CONCLUSION: Fracture healing with osteopathy in TMM is characterized by a lack of trauma without future complications. This therapy makes the concept of fracture healing develop in the direction of humanity, behaviorism and integration.展开更多
基金Project(111gpy06) supported by Fundamental Research Funds for the Central Universities,ChinaProject(101055807) supported by the Innovative Experiment Plan for College Students of Sun Yat-sen University,ChinaProject(KF201115) supported by the Opening Fund of Laboratory Sun Yat-sen University,China
文摘To study the alternating current （AC） impedance properties of Ag/AgC1 electrocardiograph （ECG） electrodes, the electrode pair was gel-to-gel connected, and then the electrical potential was recorded after a safe stimulating current passes through the electrode pair, so the AC impedance data of ECG electrodes were obtained. Varying the frequency and value of stimulating current, the detailed comparison and analysis of AC impedance properties of the electrodes were performed, and the stability was further characterized by using the continuous measurement within 24 h. The experimental results show that the AC impedance values of electrodes decreased, and then slightly increased with the increase of frequency of stimulating current. The minimum AC impedance value was obtained when the frequency was changed to 10 kHz. When the stimulating current increased, the AC impedance values of electrodes showed a slight decrease, but did not change significantly. Besides, the continuous measurement results show that the impedance value presented a significant increase in the initial 30 min, and then was stabilized in the following measuring process.
基金supported by the National Natural Science Foundation of China (21375134, 21475140, 21135006, 21321003)The National Basic Research Program of China (2015CB856300)the Chinese Academy of Sciences
文摘The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens, which is a straight-forward way for targeted analysis. However, there are still limitations during the practical applications due to the big size of the antibodies, which accelerate the discovery of small molecular probes. Peptides built from various optional building blocks and easily achieved by chemical synthetic approaches with predictable conformations, are versatile and can act as tailor-made targeting vehicles.In this mini review, we summarize the recent developments in the discovery of novel peptides for bioanalytical and biomedical applications. Progresses in peptide-library design and selection strategies are presented. Recent achievements in the peptide-guided detection, imaging and disease treatment are also focused.
基金Supported by the Project of the 2009 State Natural Science Fund (No. 30960518)a Project of the 2012 State Natural Science Fund (No. 81260513)a Major Project of the Scitech Plan of the Inner Mongolian Autonomous Region(2010-2012)
文摘OBJECTIVE: To explore the concept and norm of fracture healing with osteopathy in traditional Mongolian medicine (TMM). METHODS: Based on the correspondence between man and the universe (including psychosomatic integration) in fracture healing with osteopathy in TMM, we used modern physio-psychological and biomechanical principles and methods to probe the integrated, dynamic and functional characteristics of fracture healing. RESULTS: Based on the integration of limbs and the body, unification of the body and function and harmony of man and nature (including psychoso-matic integration), fracture healing with osteopathy in TMM comprises the concept of natural functional healing of fractures, and follows the norm of considering physiological healing and psychological function as well as limb healing and motor function. CONCLUSION: Fracture healing with osteopathy in TMM is characterized by a lack of trauma without future complications. This therapy makes the concept of fracture healing develop in the direction of humanity, behaviorism and integration.
