OBJECTIVE: Plants produce a variety of useful bio- active materials that have been used to cure differ- ent ailments of human beings. With the same idea in mind, the crude methanolic extract and various fractions of ...OBJECTIVE: Plants produce a variety of useful bio- active materials that have been used to cure differ- ent ailments of human beings. With the same idea in mind, the crude methanolic extract and various fractions of Solanum surrattense were screened for antibacterial, antifungal, phytotoxic and heamag- glutination activities. METHODS: Standardized assays were followed for the determination of antibacterial, antifungal phy- totoxic and heamagglutination activity. RESULTS: The results of the antibacterial showed that crude methanolic extract was significantly ac- tive against Staphylococcus aureus (86%) The n- hexane fraction showed good activity against Pseu- domonas aerogenosa (66.6%) and Bacillus subtilus (66.6%). The crude methanolic extract and various fractions were inactive against all test fungi. The crude methanolic extract, n-hexane, CHCI3 and aqueous fractions showed moderate phytotoxic ac- tivities of 46.67%, 40.00%, 33.34% and 33.34% re- spectively at 1000 pg/mL. The crude methanolic ex- tract and various fractions S. surrattense were un- able to aqqlutinate RBCs of the human blood indi-cating that this species lack phytolectins. CONCLUSION: The test sample showed significant antibacterial activity, no antifungal and heamagglu- tination activity while moderate phytotoxic was ob- served against Lemna minor L.展开更多
文摘OBJECTIVE: Plants produce a variety of useful bio- active materials that have been used to cure differ- ent ailments of human beings. With the same idea in mind, the crude methanolic extract and various fractions of Solanum surrattense were screened for antibacterial, antifungal, phytotoxic and heamag- glutination activities. METHODS: Standardized assays were followed for the determination of antibacterial, antifungal phy- totoxic and heamagglutination activity. RESULTS: The results of the antibacterial showed that crude methanolic extract was significantly ac- tive against Staphylococcus aureus (86%) The n- hexane fraction showed good activity against Pseu- domonas aerogenosa (66.6%) and Bacillus subtilus (66.6%). The crude methanolic extract and various fractions were inactive against all test fungi. The crude methanolic extract, n-hexane, CHCI3 and aqueous fractions showed moderate phytotoxic ac- tivities of 46.67%, 40.00%, 33.34% and 33.34% re- spectively at 1000 pg/mL. The crude methanolic ex- tract and various fractions S. surrattense were un- able to aqqlutinate RBCs of the human blood indi-cating that this species lack phytolectins. CONCLUSION: The test sample showed significant antibacterial activity, no antifungal and heamagglu- tination activity while moderate phytotoxic was ob- served against Lemna minor L.