Biological and synthetic surfactants were compared in terms of their ability to reduce interfacial tension, change the thermodynamic characteristics of a pre-conditioned surface, and to modify the rheological properti...Biological and synthetic surfactants were compared in terms of their ability to reduce interfacial tension, change the thermodynamic characteristics of a pre-conditioned surface, and to modify the rheological properties of their respective formulations at two different temperatures. Both classes of suffactants were able to reduce the inteffacial tension of their formulations to a similar level. However, the biosurfactants were more effective than the synthetics surfactants. Biosurfactants also altered the surface properties of stainless steel, rendering it hydrophilic. Microbial adhesion to stainless steel conditioned with biosurfactants was found to be thermodynamically unfavorable for all microbial strains tested. A linear relationship between shear stress and shear rate was obtained across a range of experimental conditions for all surfactant mixtures, indicating that all formulations behaved as Newtonian fluids.展开更多
The present study aims to investigate the genotype-phenotype correlation of the hereditary hemochromatosis (HH), a genetic disorder of iron metabolism, in Matera province (Basilicata, Italy). Integrating both epid...The present study aims to investigate the genotype-phenotype correlation of the hereditary hemochromatosis (HH), a genetic disorder of iron metabolism, in Matera province (Basilicata, Italy). Integrating both epidemiological and molecular approaches, the authors studied: (a) the frequency of the HH main mutations; (b) the association between mutations and HH cases. The majority of patients with HH are homozygous for the C282Y mutation of the HFE gene. A second mutation (H63D) is more widely distributed and its connection with HH isn't clear, but a low penetrance is attributed to this variant. The population-based study consists of three steps: (1) determination of iron biochemical parameters, (2) genetic test, and (3) sequencing of HFE gene and bioinformatics studies. A case report is presented in a 41-year-old male (genotype: H63D/wt) with biochemical and clinical evidences of HH, in absence of secondary iron overload factors. In the cohort of studied patients (150M:62F), there are 18 homozygous patients; H63D/H63D genotype is found in 11 cases. In the heterozygous group, H63D/wt is the predominant genotype (61/68 subjects). All the H63D/wt residents in the same village (Mont.) show altered biochemical parameter levels. In our case study, a substitution localized into the HFE promoter (nt225A 〉 C) is found. Results show that the H63D genotype is responsible for most cases of HH. The peculiar clinical manifestation found in Mont. suggests a founder effect. In our case, the iron overload is related to a presence of an undetected mutation, critical for the transcriptional regulation of the HFE gene.展开更多
OBJECTIVE:To verify the effects of scraping therapy on the weightlifting ability by measuring the subjective sensation,and changes of biomarkers.METHODS:Five students,who have been trained for 3 years in a sport schoo...OBJECTIVE:To verify the effects of scraping therapy on the weightlifting ability by measuring the subjective sensation,and changes of biomarkers.METHODS:Five students,who have been trained for 3 years in a sport school in China were participated in this study.A course of scraping therapy was applied to intervene during the normal 7-week of weightlifting training programme.The ability of weightlifting,the scale of rating perceived exertion and serum biochemical markers were measured before and after the intervention.RESULTS:Scraping therapy caused a significant increase in weightlifting ability(P<0.05).The level of rating perceived exertion remained stable with the increase in the training volume.Immuno-globulinA was significantly increased(P<0.05),and creatine kinase and blood urea nitrogen were significantly decreased(P<0.05).No significant changes were observed in white blood cell,neutrophil,and testosterone.CONCLUSION:Scraping therapy may facilitate weightlifting ability mainly by decreasing weight sensation and improving serum biochemical parameters.展开更多
Bioavailability is a key parameter in assessing contaminant transfer to biota. However, the input patterns and soil use types may impact the metal bioavailability. Several soil parameters were measured including chemi...Bioavailability is a key parameter in assessing contaminant transfer to biota. However, the input patterns and soil use types may impact the metal bioavailability. Several soil parameters were measured including chemical properties, such as pH, organic C, and Cu solution/solid speciation, and biological properties, such as soil microbial biomass C (SMBC), seed germination, and root elongation, to evaluate the bioavailability of Cu contaminated soils from three different sources, i.e., non-ferrous metal mining, Cu-based fungicides, and Cu-smelting. The results revealed that free Cu2+ ion in soil solution and the ratios of Cu fractions to total Cu content in the solid phase could not be used to predict total Cu content in soils. The indexes of seed germination and root elongation appeared not to be good biomonitors of Cu contamination in soils, which were more sensitive to soil pH and soil organic carbon (SOC). Relationships between SMBC and soil Cu forms or the ratio of SMBC/SOC and soil Cu forms showed that free Cu2+ ion and humie acid-complexed Cu could significantly inhibit soil microbial activities. Our findings suggested that both metal chemical forms and biological bioassays should be considered as a complementary technique rather than an alternative to evaluate the metal bioavailability from different pollution sources.展开更多
文摘Biological and synthetic surfactants were compared in terms of their ability to reduce interfacial tension, change the thermodynamic characteristics of a pre-conditioned surface, and to modify the rheological properties of their respective formulations at two different temperatures. Both classes of suffactants were able to reduce the inteffacial tension of their formulations to a similar level. However, the biosurfactants were more effective than the synthetics surfactants. Biosurfactants also altered the surface properties of stainless steel, rendering it hydrophilic. Microbial adhesion to stainless steel conditioned with biosurfactants was found to be thermodynamically unfavorable for all microbial strains tested. A linear relationship between shear stress and shear rate was obtained across a range of experimental conditions for all surfactant mixtures, indicating that all formulations behaved as Newtonian fluids.
文摘The present study aims to investigate the genotype-phenotype correlation of the hereditary hemochromatosis (HH), a genetic disorder of iron metabolism, in Matera province (Basilicata, Italy). Integrating both epidemiological and molecular approaches, the authors studied: (a) the frequency of the HH main mutations; (b) the association between mutations and HH cases. The majority of patients with HH are homozygous for the C282Y mutation of the HFE gene. A second mutation (H63D) is more widely distributed and its connection with HH isn't clear, but a low penetrance is attributed to this variant. The population-based study consists of three steps: (1) determination of iron biochemical parameters, (2) genetic test, and (3) sequencing of HFE gene and bioinformatics studies. A case report is presented in a 41-year-old male (genotype: H63D/wt) with biochemical and clinical evidences of HH, in absence of secondary iron overload factors. In the cohort of studied patients (150M:62F), there are 18 homozygous patients; H63D/H63D genotype is found in 11 cases. In the heterozygous group, H63D/wt is the predominant genotype (61/68 subjects). All the H63D/wt residents in the same village (Mont.) show altered biochemical parameter levels. In our case study, a substitution localized into the HFE promoter (nt225A 〉 C) is found. Results show that the H63D genotype is responsible for most cases of HH. The peculiar clinical manifestation found in Mont. suggests a founder effect. In our case, the iron overload is related to a presence of an undetected mutation, critical for the transcriptional regulation of the HFE gene.
文摘OBJECTIVE:To verify the effects of scraping therapy on the weightlifting ability by measuring the subjective sensation,and changes of biomarkers.METHODS:Five students,who have been trained for 3 years in a sport school in China were participated in this study.A course of scraping therapy was applied to intervene during the normal 7-week of weightlifting training programme.The ability of weightlifting,the scale of rating perceived exertion and serum biochemical markers were measured before and after the intervention.RESULTS:Scraping therapy caused a significant increase in weightlifting ability(P<0.05).The level of rating perceived exertion remained stable with the increase in the training volume.Immuno-globulinA was significantly increased(P<0.05),and creatine kinase and blood urea nitrogen were significantly decreased(P<0.05).No significant changes were observed in white blood cell,neutrophil,and testosterone.CONCLUSION:Scraping therapy may facilitate weightlifting ability mainly by decreasing weight sensation and improving serum biochemical parameters.
基金Supported by the National Natural Science Foundation of China(No.41101305)
文摘Bioavailability is a key parameter in assessing contaminant transfer to biota. However, the input patterns and soil use types may impact the metal bioavailability. Several soil parameters were measured including chemical properties, such as pH, organic C, and Cu solution/solid speciation, and biological properties, such as soil microbial biomass C (SMBC), seed germination, and root elongation, to evaluate the bioavailability of Cu contaminated soils from three different sources, i.e., non-ferrous metal mining, Cu-based fungicides, and Cu-smelting. The results revealed that free Cu2+ ion in soil solution and the ratios of Cu fractions to total Cu content in the solid phase could not be used to predict total Cu content in soils. The indexes of seed germination and root elongation appeared not to be good biomonitors of Cu contamination in soils, which were more sensitive to soil pH and soil organic carbon (SOC). Relationships between SMBC and soil Cu forms or the ratio of SMBC/SOC and soil Cu forms showed that free Cu2+ ion and humie acid-complexed Cu could significantly inhibit soil microbial activities. Our findings suggested that both metal chemical forms and biological bioassays should be considered as a complementary technique rather than an alternative to evaluate the metal bioavailability from different pollution sources.