The typical features of the coordinate and the curvature as well as the recorded time information were analyzed in the hand-written signatures.In the hand-written signature process 10 biometric features were summarize...The typical features of the coordinate and the curvature as well as the recorded time information were analyzed in the hand-written signatures.In the hand-written signature process 10 biometric features were summarized:the amount of zero speed in direction x and direction y,the amount of zero acceleration in direction x and direction y,the total time of the hand-written signatures,the total distance of the pen traveling in the hand-written process,the frequency for lifting the pen,the time for lifting the pen,the amount of the pressure higher or lower than the threshold values.The formulae of biometric features extraction were summarized.The Gauss function was used to draw the typical information from the above-mentioned biometric features,with which to establish the hidden Markov mode and to train it.The frame of double authentication was proposed by combing the signature with the digital signature.Web service technology was applied in the system to ensure the security of data transmission.The training practice indicates that the hand-written signature verification can satisfy the needs from the office automation systems.展开更多
The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens...The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens, which is a straight-forward way for targeted analysis. However, there are still limitations during the practical applications due to the big size of the antibodies, which accelerate the discovery of small molecular probes. Peptides built from various optional building blocks and easily achieved by chemical synthetic approaches with predictable conformations, are versatile and can act as tailor-made targeting vehicles.In this mini review, we summarize the recent developments in the discovery of novel peptides for bioanalytical and biomedical applications. Progresses in peptide-library design and selection strategies are presented. Recent achievements in the peptide-guided detection, imaging and disease treatment are also focused.展开更多
基金Project(03JJY3102) supported by the Natural Science Foundation of Hunan Province, China
文摘The typical features of the coordinate and the curvature as well as the recorded time information were analyzed in the hand-written signatures.In the hand-written signature process 10 biometric features were summarized:the amount of zero speed in direction x and direction y,the amount of zero acceleration in direction x and direction y,the total time of the hand-written signatures,the total distance of the pen traveling in the hand-written process,the frequency for lifting the pen,the time for lifting the pen,the amount of the pressure higher or lower than the threshold values.The formulae of biometric features extraction were summarized.The Gauss function was used to draw the typical information from the above-mentioned biometric features,with which to establish the hidden Markov mode and to train it.The frame of double authentication was proposed by combing the signature with the digital signature.Web service technology was applied in the system to ensure the security of data transmission.The training practice indicates that the hand-written signature verification can satisfy the needs from the office automation systems.
基金supported by the National Natural Science Foundation of China (21375134, 21475140, 21135006, 21321003)The National Basic Research Program of China (2015CB856300)the Chinese Academy of Sciences
文摘The complicated, highly dynamic and diverse nature of biosystems brings great challenges to the specific analysis of molecular processes of interest. Nature provides antibodies for the specific recognition of antigens, which is a straight-forward way for targeted analysis. However, there are still limitations during the practical applications due to the big size of the antibodies, which accelerate the discovery of small molecular probes. Peptides built from various optional building blocks and easily achieved by chemical synthetic approaches with predictable conformations, are versatile and can act as tailor-made targeting vehicles.In this mini review, we summarize the recent developments in the discovery of novel peptides for bioanalytical and biomedical applications. Progresses in peptide-library design and selection strategies are presented. Recent achievements in the peptide-guided detection, imaging and disease treatment are also focused.
