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医用生物胶水用于包皮环切术的护理观察 被引量:4
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作者 蔡春琴 《护士进修杂志》 北大核心 2005年第4期376-376,共1页
关键词 医用生物胶水 包皮环切术 护理
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生物组织胶水用于血管吻合口漏血封堵的实验研究 被引量:1
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作者 程晓松 《中国社区医师》 2017年第36期5-6,共2页
目的:建立生物组织胶水用于血管吻合口漏血封堵的动物模型,并探讨该吻合方法与传统全缝线吻合方法在血管吻合方面的对比优势。方法:利用SD大鼠腹主动脉制作血管吻合模型,记录两种吻合方法的吻合时间及通畅率;术后6周取吻合口周围血管做H... 目的:建立生物组织胶水用于血管吻合口漏血封堵的动物模型,并探讨该吻合方法与传统全缝线吻合方法在血管吻合方面的对比优势。方法:利用SD大鼠腹主动脉制作血管吻合模型,记录两种吻合方法的吻合时间及通畅率;术后6周取吻合口周围血管做HE染色,观察吻合口周围的炎性反应。结果:新型吻合方法比传统全缝线吻合法所需时间更短(P<0.05),两种吻合方法通畅率差异无统计学意义(P>0.05),新型吻合方法吻合口周围炎性细胞数量明显少于传统吻合法(P<0.05)。结论:生物组织胶水能有效运用于血管吻合口漏血的封堵,且减少了缝针数量,比传统缝合法简便、快捷,能够有效减少吻合口周围炎性反应,且拥有与传统吻合法相近的通畅率,是一种安全、可靠的血管吻合方法。 展开更多
关键词 生物组织胶水 血管吻合 全缝线吻合
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胶粘剂——结构和研究进展 被引量:1
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作者 刘子洋 《当代化工研究》 2017年第8期108-109,共2页
作为高分子材料中的一员,胶粘剂很早就被人类开始使用,直到现在胶粘剂仍在我们生活中有着不可或缺的作用,本文向大家介绍了不同种类胶粘剂的结构,以及胶粘剂的未来发展方向。
关键词 胶黏剂 酚醛树脂 理论研究 结构 生物胶水
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生物组织胶水用于眼睑面部皮肤撕裂伤应用效果与护理 被引量:2
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作者 杜哲 《国际护理学杂志》 2014年第12期3596-3598,共3页
目的:对于应用生物组织胶水处理眼睑面部皮肤撕裂伤的应用效果和护理注意事项进行总结,为今后的相关临床工作提供参考。方法对随机抽取的2013年3月至2014年3月间在河北省眼科医院就诊的100例眼睑面部皮肤有撕裂伤的患者应用生物组织... 目的:对于应用生物组织胶水处理眼睑面部皮肤撕裂伤的应用效果和护理注意事项进行总结,为今后的相关临床工作提供参考。方法对随机抽取的2013年3月至2014年3月间在河北省眼科医院就诊的100例眼睑面部皮肤有撕裂伤的患者应用生物组织胶水进行处理,观察并比较分析其与同一时段内用传统手术缝合的100例患者的疗效差异。结果试验组的处理时间(137.2±8.3)s,明显少于对照组(531.5±13.6)s,差异有统计学意义(P<0.05);使用生物组织胶水的试验组比用传统手术缝合处理的对照组患者伤口愈合要好,手术疼痛更轻微,试验组除了2例出现伤口开裂外,其余患者均愈合良好,试验组的患者98%反应为0级疼痛感;试验组优良比例高达77%,试验组家属满意度91%,显著高于对照组69%,差异有统计学意义( P<0.05)。结论出现眼睑皮肤撕裂伤时应用生物组织胶水进行处理,具有效果显著,操作简单,疼痛轻微,患者及家属满意度高等优点,同时术后的精心护理工作也具有重要意义,临床应用价值大。 展开更多
关键词 生物组织胶水 皮肤撕裂伤 应用效果 护理
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Observations on shell growth and morphology of the bivalve Ruditapes philippinarum
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作者 范德江 张爱滨 +1 位作者 杨作升 孙效功 《Chinese Journal of Oceanology and Limnology》 SCIE CAS CSCD 2007年第3期322-329,共8页
The bivalve Ruditapes philippinarum is not only one of the main mollusc species in the west Pacific Ocean, but also one of the main species for aquaculture in China. Knowledge of growth of the R. philippinarum shell w... The bivalve Ruditapes philippinarum is not only one of the main mollusc species in the west Pacific Ocean, but also one of the main species for aquaculture in China. Knowledge of growth of the R. philippinarum shell will improve our understanding of the shell as an environmental archive. It is also useful for the aquaculture of R. philippinarum. In this research, a hanging box culture method was introduced in the culture of R. philippinarum. The bivalves were cultured for 126 days, from March 31 to August 3, 2002. The average growth rates of shell width, height, and thickness were 0.069, 0.046, and 0.032 mm/d, respectively. The mean increase of average individual wet mass was 0.028 g/d. The largest growth rates of both shell and average individual wet mass occurred in June, indicating that water temperature and bivalve reproduction were 2 important factors. The shell morphology underwent significant changes with shell growth. The ratio of height to thickness (value of B/C) shifted 1.58 in the first 60 days to 1.54 in the last 30 days, which was resulted from the change in major shell growth direction. Periodic changes in the B/C ratio led to corrugated shell form, which could be used to determine the age of the shell. 展开更多
关键词 Jiaozhou Bay bivalve Ruditapes philippinarum growth rate MORPHOLOGY hanging box culture
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Assessment of Sericin Biosorbent for Selective Dye Removal 被引量:2
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作者 CHEN Xinqing LAM Koon Fung +3 位作者 MAK Shuk Fong CHING Wai Kwong NG Tsz Nok YEUNG King Lun 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2012年第3期426-432,共7页
The silk sericin is the main residue in silk production and it is found to be a low cost and efficient bio-sorbent. In this study, sericin was characterized with various techniques including SEM (scanning electron mi... The silk sericin is the main residue in silk production and it is found to be a low cost and efficient bio-sorbent. In this study, sericin was characterized with various techniques including SEM (scanning electron micro- scope), XRD, N2 physisorption, FTIR (Fourier transformed infrared spectroscopy) and XPS (X-ray photoelectron spectroscopy). The nitrogen content of sericin was ca. 8.5 mmol.g-1 according to elemental analysis. Dye adsorption by sericin biosorbent was investigated with the acid yellow (AY), methylene blue (MB) and copper (II) phthalocyanine-3,4'4"4'"-tetrasulfonic acid (CuPc) dyes from water. Sericin displayed large capacity for AY andCuPc adsorption with adsorption capacities of respectively 3.1 and 0.35 mmol.g-1, but it did not adsorbed methyl- ene blue dye. This selectivity is due to the basicity of amide groups in seriein biosorbents. 展开更多
关键词 dye adsorption silk protein BIOSORBENT
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Screening of Toxin Mutant of Dickeya zeae and Its Biological Characters
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作者 Jingyi ZHANG Yutao WANG +1 位作者 Yanchang LI Qiongguang LIU 《Agricultural Science & Technology》 CAS 2013年第10期1397-1402,共6页
[Objective]This study aimed to screen toxin mutant of Dickeya zeae(Erwinia chrysanthemi pv.zeae)and investigate its biological characters.[Method]We obtained a toxin mutant strain D.zeae Ech7-3-42 by using acridine or... [Objective]This study aimed to screen toxin mutant of Dickeya zeae(Erwinia chrysanthemi pv.zeae)and investigate its biological characters.[Method]We obtained a toxin mutant strain D.zeae Ech7-3-42 by using acridine orange as a mutagenic agent and compared their biological characteristics and virulence between the toxin mutant and wild strain.[Result]There was no significant difference in pectin lyase,protease,cellulase and the production of extracellular polysaccharide and lipopolysaccharide,but significant difference in toxin biological activities and virulence.Ech7-3-42 mutant did not produce toxin,as well as the loss of virulence on rice and HR on tobacco,but did not lose the ability to soft rot on potato.Mutant strain Ech7-3-42 can infect rice root and then enriched in the root neck and stalk,but it could not cause rice foot rot.Dickeya zeae(wild and mutant strain)could be detected by PCR in the root neck and below the 1-2 cm long stem area,but could not be detected in the leaves.[Conclusion]We believed that toxin may be one of the important factors for D.zeae virulence on rice. 展开更多
关键词 Dickeya zeae TOXIN VIRULENCE Extracellular enzyme Extracellular polysaccharide
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Supramolecular protein glue to boost enzyme activity 被引量:2
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作者 Yuna Shang Yue Liao +5 位作者 Zhongju Ye Zhongyan Wang Lehui Xiao Jie Gao Qigang Wang Zhimou Yang 《Science China Materials》 SCIE EI CSCD 2019年第9期1341-1349,共9页
Proteins possess many biological functions.However, they can easily degrade or aggregate, thus losing their bioactivity. Therefore, it is very important to develop materials capable of interacting with proteins and fo... Proteins possess many biological functions.However, they can easily degrade or aggregate, thus losing their bioactivity. Therefore, it is very important to develop materials capable of interacting with proteins and forming nanostructures for protein storage and delivery. In this study,we serendipitously found a novel peptide-based supramolecular protein glue(Nap-GFFYK(γE)2-NH2, compound 1) that could co-assemble with proteins into nanofibers and hydrogels. We found that compound 1 rapidly folded into a β-sheet conformation upon contact with many proteins but not with polymers. Total internal reflection fluorescence microscopy(TIRFM) images clearly show the formation of co-assembled nanofibers by proteins and the peptide. The supramolecular protein glue could improve the dispersion of enzymes(lipase and lysozyme) and therefore enhance their catalytic activity,especially at high temperatures. More importantly, the supramolecular protein glue could co-assemble with two enzymes, glucose oxidase/horseradish peroxidase(GOx/HRP)and GOx/cytochrome c(cyt c), to form nanofibers that significantly enhanced the catalytic activity of tandem enzymatic reactions. We envisioned the great potential of our supramolecular protein glue for protein storage, delivery, and bioactivity manipulation. 展开更多
关键词 protein glue coassemble Β-SHEET enzyme activity
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A cementation method of loose particles based on microbe-based cement 被引量:8
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作者 RONG Hui QIAN ChunXiang WANG RuiXing 《Science China(Technological Sciences)》 SCIE EI CAS 2011年第7期1722-1729,共8页
Microbe-based cement has been widely reported in recent literatures. It is a new method of consolidating loose fine particles, which relies on the bacterially induced formation of a compatible carbonate precipitation ... Microbe-based cement has been widely reported in recent literatures. It is a new method of consolidating loose fine particles, which relies on the bacterially induced formation of a compatible carbonate precipitation around individual particles and at particle-particle contacts. Materials and cementation procedure are two major factors that influence the cementation performance of microbe-based cement. Besides, there are some other factors related to the performance, such as pH, temperature, metabolism activity, the flushed times of bacterial solution, concentration of substrate and calcium ion, etc., which affect consolidation function. The assessment methods for cementation process are carried out by various techniques. The performance of consolidation loose grains based on microbe-based cement is tested with the help of experiment. In this paper a review is presented on the cementation mechanism of microbe-based cement, techniques utilized to monitor cementation process, the consolidated performance by microbe-based cement and bond factors. 展开更多
关键词 microbe-based cement bacteria loose particles consolidation carbonate precipitation compressive strength permeability porosity
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Underwater flexible mechanoreceptors constructed by anti-swelling self-healable hydrogel 被引量:4
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作者 Xin Liu Qin Zhang +1 位作者 Fei Jia Guanghui Gao 《Science China Materials》 SCIE EI CAS CSCD 2021年第12期3069-3078,共10页
Wet-resistant flexible electronics have acquired increasing attention on applications in wet environments,such as sweaty skin, rainy weather, biological fluids, and underwater. However, it remains challenging to achie... Wet-resistant flexible electronics have acquired increasing attention on applications in wet environments,such as sweaty skin, rainy weather, biological fluids, and underwater. However, it remains challenging to achieve nonswelling and underwater self-healing hydrogel sensors for the mechanical perception in aqueous solutions. Herein, a selfhealing and non-swellable hydrogel is successfully fabricated,which presents an automatically healing behavior in various aquatic environments, including deionized water, seawater,sweat, alkali and acidic aqueous solutions. Moreover, the hydrogel demonstrates high stretchability and stable electromechanical sensing properties in water. Furthermore, an electronic skin is designed with the features of fast responsiveness, reliability, and high sensitivity for detecting breathing, speaking, coughing, and diverse body movements. The self-healing hydrogel sensors enable a brilliant mechanical sensibility for detecting a series of dynamic stimuli in air and underwater, even after the healing of fracture interface in water. The underwater self-healing and anti-swelling hydrogel would provide enticing potential on various stable electronic devices for aquatic environments, such as implantable electrodes, triboelectric nanogenerators, and underwater soft robotics. 展开更多
关键词 HYDROGEL water-insensitive electronics underwater self-healing anti-swelling underwater sensing
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In situ forming chitosan-based hydrogel as a lung sealant for biological lung volume reduction 被引量:1
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作者 Titima Songkroh 谢红国 +6 位作者 于炜婷 吕国军 刘袖洞 王林 孙广炜 徐小溪 马小军 《Science Bulletin》 SCIE EI CAS CSCD 2015年第2期235-240,I0002,共7页
Biological lung volume reduction (BLVR) using lung sealant has received more attention recently as a new non-surgical approach to emphysema treatment. Many tissue sealants have been studied but only a few have been ... Biological lung volume reduction (BLVR) using lung sealant has received more attention recently as a new non-surgical approach to emphysema treatment. Many tissue sealants have been studied but only a few have been proposed for BLVR. In this work, we prepared in situ forming chitosan-based hydrogels (CSG) using covalent cross-linking of chitosan and genipin in the cooperation of ionic interaction between chitosan and sodium orthophosphate hydrate (Na3PO4.12H20) and characterized by Fourier transform infrared spectroscopy, scanning electron microscopy and rheological methods. CSG showed short gelation time (8 min), high swelling ratio (〉100 %) and non-toxicity (3T3 mouse fibroblast cell viability 〉80 %) under physiological conditions. The application of lung sealant for BLVR was tested in a Chinese dog and evaluated by chest computed tomography. After 3 weeks of the installation of CSG in bronchopulmonary segment, the gel formation was detected at a localized region of bronchi and the local atelectasis occurred. Our findings indicate that this chitosan-based hydrogel is a promising new candidate for use as a lung sealant for BLVR. 展开更多
关键词 Chitosan based hydrogels Biological lung volume reduction Lung sealants EMPHYSEMA
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Designing the mechanical properties of peptide-based supramolecular hydrogels for biomedical applications 被引量:2
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作者 LI Ying QIN Meng +1 位作者 CAO Yi WANG Wei 《Science China(Physics,Mechanics & Astronomy)》 SCIE EI CAS 2014年第5期849-858,共10页
Hydrogels are a class of special materials that contain a large amount of water and behave like rubber.These materials have found broad applications in tissue engineering,cell culturing,regenerative medicine etc.Recen... Hydrogels are a class of special materials that contain a large amount of water and behave like rubber.These materials have found broad applications in tissue engineering,cell culturing,regenerative medicine etc.Recently,the exploration of peptide-based supramolecular hydrogels has greatly expanded the repertoire of hydrogels suitable for biomedical applications.However,the mechanical properties of peptide-based hydrogels are intrinsically weak.Therefore,it is crucial to develop methods that can improve the mechanical stability of such peptide-based hydrogels.In this review,we explore the factors that determine or influence the mechanical stability of peptide-based hydrogels and summarize several key elements that may guide scientists to achieve mechanically improved hydrogels.In addition,we exemplified several methods that have been successfully developed to prepare hydrogels with enhanced mechanical stability.These mechanically strong peptide-based hydrogels may find broad applications as novel biomaterials.It is still challenging to engineer hydrogels in order to mimic the mechanical properties of biological tissues.More hydrogel materials with optimal mechanical properties suitable for various types of biological applications will be available in the near future. 展开更多
关键词 low molecular weight gelators (LMWG) peptide-based hydrogel hydrogelation mechanical properties (stability) MODULUS rheology
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Flexible electrostatic hydrogels from marine organism for nitric oxide-enhanced photodynamic therapy against multidrug-resistant bacterial infection 被引量:1
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作者 Yujie Sun Rong-Lai Wen +6 位作者 Dan Yu Yiwen Zhu Liang Zheng Xiangdong Liu Haoran Wang Bingran Yu Fu-Jian Xu 《Science China Materials》 SCIE EI CAS CSCD 2022年第10期2850-2860,共11页
The abuse of antibiotics in treating microbial infections has led to the emergence and prevalence of drugresistant bacteria.Thus,the development of novel antibacterial materials is attracting increasing attention.Here... The abuse of antibiotics in treating microbial infections has led to the emergence and prevalence of drugresistant bacteria.Thus,the development of novel antibacterial materials is attracting increasing attention.Here,a series of flexible electrostatic hydrogels with excellent antibacterial ability were constructed using a mixture of nitric oxide(NO)-releasing nitrated chitosan(CSNO)and mesotetra(4-carboxyphenyl)porphine(TCPP)with salmon sperm DNA(ssDNA)solution.When cultured with gram-negative bacteria under solar simulator irradiation,TCPP-CSNO_(m)ssDNA_(n) hydrogels released reactive oxygen species(ROS)and NO to produce peroxynitrite ions(ONOO^(−)).ONOO−is efficient at killing bacteria,thereby improving the antimicrobial ability of photodynamic therapy against gram-negative bacteria.The hydrogels exhibited powerful antibacterial activity in vivo when used to treat skin infections caused by drugresistant bacteria,making them a promising candidate for clinical applications.A string of antibacterial hydrogels that release ROS and NO synergistically can bring new possibilities for effectively killing drug-resistant bacteria and be of great value in anti-infection wound dressings and other applications. 展开更多
关键词 electrostatic hydrogel drug-resistant bacteria PEROXYNITRITE photodynamic therapy
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