研究旨在设计一款实用便携、应用范围广的耳聋耳鸣康复仪,在功能上增加了单片机控制治疗强度,帮助患者恢复听力,重获健康。根据穴位的电阻抗特异性,设计阈值可调的探穴电路;设计波形发生器产生波形驱动耳机发声,实现频率、分贝连续可调...研究旨在设计一款实用便携、应用范围广的耳聋耳鸣康复仪,在功能上增加了单片机控制治疗强度,帮助患者恢复听力,重获健康。根据穴位的电阻抗特异性,设计阈值可调的探穴电路;设计波形发生器产生波形驱动耳机发声,实现频率、分贝连续可调的纯音刺激源,液晶实时显示并记录患者听阈值;采用白噪声治疗,通过三极管基极-集电极齐纳击穿产生白噪声,强度可调节;设计生物脉冲产生电路,经过倍压电路升压,瞬间放电会有类似针灸的感觉,作用于人体穴位用于治疗;液晶显示治疗强度,按键控制电路输出强度。经过大量实验,结果表明,探穴准确率高达95%;纯音刺激源频率和分贝满足听阈值检测的要求,频率为20 Hz^20 k Hz,分贝为0~90 d B;生物脉冲刺激强度不超过人体安全电流、安全电压。本项目研究的耳聋耳鸣康复仪操作简单、实用、便携,符合当代耳聋耳鸣康复仪发展趋势,为进一步实现耳聋耳鸣患者有效的康复治疗提供了良好的帮助。展开更多
The biodegradability and biocompatibility of porous Mg-2Zn（mass fraction, %） scaffolds coated with nano hydroxyapatite（HAP） were investigated. The nano HAP coating on Mg-2Zn scaffolds was prepared by the pulse ele...The biodegradability and biocompatibility of porous Mg-2Zn（mass fraction, %） scaffolds coated with nano hydroxyapatite（HAP） were investigated. The nano HAP coating on Mg-2Zn scaffolds was prepared by the pulse electrodeposition method. The as-deposited scaffolds were then post-treated with alkaline solution to improve the biodegradation behavior and biocompatibility for implant applications. The microstructure and composition of scaffold and nano HAP coating, as well as their degradation and cytotoxicity behavior in simulated body fluid（SBF） were investigated. The post-treated coating is composed of needle-like HAP with the diameter less than 100 nm developed almost perpendicularly to the substrate, which exhibits a similar composition to natural bone. It is found that the products of immersion in SBF are identified to be HAP,（Ca,Mg）3（PO4）2 and Mg（OH）2. The bioactivity, biocompatibility and cell viabilities for the as-coated and post-treated scaffold extracts are higher than those for the uncoated scaffold. MG63 cells are found to adhere and proliferate on the surface of the as-coated and post-treated scaffolds, making it a promising choice for medical application. The results show that the pulse electrodeposition of nano HAP coating and alkaline treatment is a useful approach to improve the biodegradability and bioactivity of porous Mg-Zn scaffolds.展开更多
The effect of repetitive pulsed microwaves （10 GHz, pulse duration of 100-300 ns, pulse repetition rate of 4-25 pulse per second, peak power density of 0.04-3.5 kW/cm^2） on mastocytoma P815, Ehrlich carcinoma, norma...The effect of repetitive pulsed microwaves （10 GHz, pulse duration of 100-300 ns, pulse repetition rate of 4-25 pulse per second, peak power density of 0.04-3.5 kW/cm^2） on mastocytoma P815, Ehrlich carcinoma, normal spleen cells and wound healing was investigated. It was found that short-time irradiation with an intensity of 0.9-1.5 kW/cm^2 inhibited proliferation of tumor cells in vitro, whereas at same time it contributes to proliferation of normal spleen cells in vitro. The repetitive pulsed microwaves with an intensity of 0.04-1.5 kW/cm^2 stimulated healing of skin wounds and ulcerations in mice. The effects showed a dependence on the pulse repetition rate and irradiation intensity.展开更多
This work aims to control pulsed power for biomedical fields, which demands sensitive parameters. The pulsed power consists of a voltage rise time of less than 50 ns and charging energy to 1.0 J/pulse; also, the pulse...This work aims to control pulsed power for biomedical fields, which demands sensitive parameters. The pulsed power consists of a voltage rise time of less than 50 ns and charging energy to 1.0 J/pulse; also, the pulse control area includes pulse interval pulse shot number, output voltage. To achieve this system, a pulsed power system exists including software running on PC, universal serial bus （UgB~ for connection, and FPGA controller. Using the software for complex control of pulsed power will enable expansion into various fields with easy operation.展开更多
Along with the development of biomedical ergigineering, negative pressure aspirator is more and more widely applied in clinical treatment and patients rescuing. The study of negative pressure aspi- rator is an importa...Along with the development of biomedical ergigineering, negative pressure aspirator is more and more widely applied in clinical treatment and patients rescuing. The study of negative pressure aspi- rator is an important goal pursued in emergency treatment, became it can boost aid success. Given this need, this device based on MXT8051 single-chip is developed. The device can use Pulse Width Modulation （PWM） signal to drive the motor of negative pressure pump and it can adjust the motor＇s speed through the Proportional In- tegral Derivative （PID） algorithm to realize the setting negative pressure rapidly, aoctarately and stably. The control requiroemnt is accomplishedthrough the nmn-machine interface. This device has the advantage of simple operation, low cost and good practicability.展开更多
文摘研究旨在设计一款实用便携、应用范围广的耳聋耳鸣康复仪,在功能上增加了单片机控制治疗强度,帮助患者恢复听力,重获健康。根据穴位的电阻抗特异性,设计阈值可调的探穴电路;设计波形发生器产生波形驱动耳机发声,实现频率、分贝连续可调的纯音刺激源,液晶实时显示并记录患者听阈值;采用白噪声治疗,通过三极管基极-集电极齐纳击穿产生白噪声,强度可调节;设计生物脉冲产生电路,经过倍压电路升压,瞬间放电会有类似针灸的感觉,作用于人体穴位用于治疗;液晶显示治疗强度,按键控制电路输出强度。经过大量实验,结果表明,探穴准确率高达95%;纯音刺激源频率和分贝满足听阈值检测的要求,频率为20 Hz^20 k Hz,分贝为0~90 d B;生物脉冲刺激强度不超过人体安全电流、安全电压。本项目研究的耳聋耳鸣康复仪操作简单、实用、便携,符合当代耳聋耳鸣康复仪发展趋势,为进一步实现耳聋耳鸣患者有效的康复治疗提供了良好的帮助。
文摘The biodegradability and biocompatibility of porous Mg-2Zn（mass fraction, %） scaffolds coated with nano hydroxyapatite（HAP） were investigated. The nano HAP coating on Mg-2Zn scaffolds was prepared by the pulse electrodeposition method. The as-deposited scaffolds were then post-treated with alkaline solution to improve the biodegradation behavior and biocompatibility for implant applications. The microstructure and composition of scaffold and nano HAP coating, as well as their degradation and cytotoxicity behavior in simulated body fluid（SBF） were investigated. The post-treated coating is composed of needle-like HAP with the diameter less than 100 nm developed almost perpendicularly to the substrate, which exhibits a similar composition to natural bone. It is found that the products of immersion in SBF are identified to be HAP,（Ca,Mg）3（PO4）2 and Mg（OH）2. The bioactivity, biocompatibility and cell viabilities for the as-coated and post-treated scaffold extracts are higher than those for the uncoated scaffold. MG63 cells are found to adhere and proliferate on the surface of the as-coated and post-treated scaffolds, making it a promising choice for medical application. The results show that the pulse electrodeposition of nano HAP coating and alkaline treatment is a useful approach to improve the biodegradability and bioactivity of porous Mg-Zn scaffolds.
文摘The effect of repetitive pulsed microwaves （10 GHz, pulse duration of 100-300 ns, pulse repetition rate of 4-25 pulse per second, peak power density of 0.04-3.5 kW/cm^2） on mastocytoma P815, Ehrlich carcinoma, normal spleen cells and wound healing was investigated. It was found that short-time irradiation with an intensity of 0.9-1.5 kW/cm^2 inhibited proliferation of tumor cells in vitro, whereas at same time it contributes to proliferation of normal spleen cells in vitro. The repetitive pulsed microwaves with an intensity of 0.04-1.5 kW/cm^2 stimulated healing of skin wounds and ulcerations in mice. The effects showed a dependence on the pulse repetition rate and irradiation intensity.
文摘This work aims to control pulsed power for biomedical fields, which demands sensitive parameters. The pulsed power consists of a voltage rise time of less than 50 ns and charging energy to 1.0 J/pulse; also, the pulse control area includes pulse interval pulse shot number, output voltage. To achieve this system, a pulsed power system exists including software running on PC, universal serial bus （UgB~ for connection, and FPGA controller. Using the software for complex control of pulsed power will enable expansion into various fields with easy operation.
文摘Along with the development of biomedical ergigineering, negative pressure aspirator is more and more widely applied in clinical treatment and patients rescuing. The study of negative pressure aspi- rator is an important goal pursued in emergency treatment, became it can boost aid success. Given this need, this device based on MXT8051 single-chip is developed. The device can use Pulse Width Modulation （PWM） signal to drive the motor of negative pressure pump and it can adjust the motor＇s speed through the Proportional In- tegral Derivative （PID） algorithm to realize the setting negative pressure rapidly, aoctarately and stably. The control requiroemnt is accomplishedthrough the nmn-machine interface. This device has the advantage of simple operation, low cost and good practicability.
