The electron information of the molecules, cholesterol, chromium-and cuppercholesterol complexes, was calculated by CNDO/M. And, using the interaction potential function method, the intermolecular interaction energies...The electron information of the molecules, cholesterol, chromium-and cuppercholesterol complexes, was calculated by CNDO/M. And, using the interaction potential function method, the intermolecular interaction energies between cholesterols, the complexes, and Cu2+ , Zn2+, Cd2+, Cr3+-cholesterol complexes were obtained. Based on the interaction energy, the medical role of biometals in hypercholesterolemia concerned with arteriosclerosis were explained successfully.展开更多
引导骨再生(guided bone regeneration, GBR)是最常见的骨增量手术,而其效果受到生物屏障膜的材料特性所影响。鉴于现有的生物屏障膜无法同时满足生物相容性好、力学强度高、降解可控、生物活性佳且易操作性等临床需求,亟待研发一种新...引导骨再生(guided bone regeneration, GBR)是最常见的骨增量手术,而其效果受到生物屏障膜的材料特性所影响。鉴于现有的生物屏障膜无法同时满足生物相容性好、力学强度高、降解可控、生物活性佳且易操作性等临床需求,亟待研发一种新型生物屏障膜材料。可降解金属(biodegradable metals, BMs)是指一种预期在体内降解的金属。其中,锌基BMs因其优异的材料特性,有望成为新一代生物屏障膜材料。然而,锌基生物屏障膜仍处于基础研究阶段。在此,笔者结合团队前期的研究工作,基于今后的临床应用考虑,系统地阐析锌基生物屏障膜在生物相容性、力学性能、降解性能和生物活性四个方面的研究进展及不足,为促进其临床转化提供科学依据。展开更多
文摘The electron information of the molecules, cholesterol, chromium-and cuppercholesterol complexes, was calculated by CNDO/M. And, using the interaction potential function method, the intermolecular interaction energies between cholesterols, the complexes, and Cu2+ , Zn2+, Cd2+, Cr3+-cholesterol complexes were obtained. Based on the interaction energy, the medical role of biometals in hypercholesterolemia concerned with arteriosclerosis were explained successfully.
