Selective cyclo-oxygenase-2 (CQX-2) inhibitor, VIOXX (rofecoxib), wasvoluntarily withdrawn worldwide from drugstores by its maker Merck & Co., Inc. on September 30,2004, for its potential lethal side effects of he...Selective cyclo-oxygenase-2 (CQX-2) inhibitor, VIOXX (rofecoxib), wasvoluntarily withdrawn worldwide from drugstores by its maker Merck & Co., Inc. on September 30,2004, for its potential lethal side effects of heart attack or stroke, The Merck' s decision wasbased on new, three-year data from a prospective, multi-center, randomized, placebo-controlled,double-blind clinical trial of VIOXX with an unrelated study, the APPROVe (Adenomatous PolypPrevention on VIOXX) trial. The trial has been enrolling 2 600 patients and comparing 156 weeks(three years) of treatment with VIOXX 25 mg to placebo since 2000.展开更多
Psychological and physiological characteristics of preschool children determine their lives should be the main game, but because of the content and the way too pre-primary school of teachers and parents give their chi...Psychological and physiological characteristics of preschool children determine their lives should be the main game, but because of the content and the way too pre-primary school of teachers and parents give their children pressure of learning early, they often give children physical and cause a series of adverse consequences of psychological, so that children lively nature is destroyed. In the development context of pre-primary schools it will not only hinder enhance children＇ s thinking ability, but also devoid of the child＇ s talent and mettle, for children to learn and live very unfavorable late. Preschool Primary School, out of the office park on the right track, is serious impediment to the normal development of preschool children and grow. This paper describes the dangers of pre-school, pre-primary schools and the causes are analyzed and we proposed the removal of the primary effective strategy, in order to fully mobilize the child＇ s lively and good mobility and lay its future development a solid foundation.展开更多
文摘Selective cyclo-oxygenase-2 (CQX-2) inhibitor, VIOXX (rofecoxib), wasvoluntarily withdrawn worldwide from drugstores by its maker Merck & Co., Inc. on September 30,2004, for its potential lethal side effects of heart attack or stroke, The Merck' s decision wasbased on new, three-year data from a prospective, multi-center, randomized, placebo-controlled,double-blind clinical trial of VIOXX with an unrelated study, the APPROVe (Adenomatous PolypPrevention on VIOXX) trial. The trial has been enrolling 2 600 patients and comparing 156 weeks(three years) of treatment with VIOXX 25 mg to placebo since 2000.
文摘Psychological and physiological characteristics of preschool children determine their lives should be the main game, but because of the content and the way too pre-primary school of teachers and parents give their children pressure of learning early, they often give children physical and cause a series of adverse consequences of psychological, so that children lively nature is destroyed. In the development context of pre-primary schools it will not only hinder enhance children＇ s thinking ability, but also devoid of the child＇ s talent and mettle, for children to learn and live very unfavorable late. Preschool Primary School, out of the office park on the right track, is serious impediment to the normal development of preschool children and grow. This paper describes the dangers of pre-school, pre-primary schools and the causes are analyzed and we proposed the removal of the primary effective strategy, in order to fully mobilize the child＇ s lively and good mobility and lay its future development a solid foundation.
