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磁性便捷纱窗
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作者 汪敬生 《农业装备技术》 1995年第1期16-16,共1页
磁性便捷纱窗安徽省安庆密封门窗厂最近制成的磁性便捷纱窗,设计合理、抗风力强、清洗容易、牢固耐用、可随意上下、无须固定。适宜于各种钢质、木质或铝合金门窗。使用时,将纱窗往窗户上一“贴”便成。、吸附牢固,无缝隙,开窗关窗... 磁性便捷纱窗安徽省安庆密封门窗厂最近制成的磁性便捷纱窗,设计合理、抗风力强、清洗容易、牢固耐用、可随意上下、无须固定。适宜于各种钢质、木质或铝合金门窗。使用时,将纱窗往窗户上一“贴”便成。、吸附牢固,无缝隙,开窗关窗运转自如,不用时揭下卷起存放;需要... 展开更多
关键词 生磁性 “贴” 铝合金门窗 密封门窗 纱窗 抗风力 设计合理 无缝隙 安徽省 安庆
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Acidthiobacillus ferrooxidans中磁小体的提取(英文) 被引量:12
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作者 谢建平 刘新星 +1 位作者 刘文斌 邱冠周 《生物磁学》 2005年第3期7-10,共4页
At.f和趋磁细菌在生理特性和生长环境有一定的相似性,而且镜检发现At.f具有趋磁性,所以本文采用了趋磁细菌中磁小体的提取方法尝试提取At.f中的磁小体,用超声波破碎At.f后,以磁铁吸取其体内的磁性颗粒,经过检测,发现其体内确实存在含铁... At.f和趋磁细菌在生理特性和生长环境有一定的相似性,而且镜检发现At.f具有趋磁性,所以本文采用了趋磁细菌中磁小体的提取方法尝试提取At.f中的磁小体,用超声波破碎At.f后,以磁铁吸取其体内的磁性颗粒,经过检测,发现其体内确实存在含铁元素的磁性颗粒。提取粗样品经过电镜分析,证实其体内存在着少量由脂质包裹的磁小体。磁小体悬浮液经过蔗糖密度梯度离心纯化后,对其作透射电镜,可以清晰的看到磁小体。实验结果表明,At.f体内存在少量的磁小体,正是由于磁小体的存在,才使得At.f在外加磁场作用下发生磁生物效应。这是首次发现从酸性矿坑水分离的At.f具有趋磁性,并从中提取到了磁小体,可以利用At.f的趋磁性将其按照不同磁性进行分离,从而获得活性高的、对不同磁性矿物有特异性的高效浸矿菌种。 展开更多
关键词 磁小体 提取方法 趋磁细菌 长环境 磁性矿物 物电磁学
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Plasma Treatment Enhanced Magnetic Properties in Manganese Doped Titanium Nitride Thin Films
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作者 李丹 许灵敏 +1 位作者 李树玮 周勋 《Chinese Journal of Chemical Physics》 SCIE CAS CSCD 2017年第4期457-460,I0002,共5页
The ferromagnetic manganese doped TiN films were grown by plasma assisted molecular beam epitaxy on MgO(001) substrates. The nitrogen concentration and the ratio of manganese at Ti lattice sites increase after the p... The ferromagnetic manganese doped TiN films were grown by plasma assisted molecular beam epitaxy on MgO(001) substrates. The nitrogen concentration and the ratio of manganese at Ti lattice sites increase after the plasma annealing post treatment. TIN(002) peak shifts toward low angle direction and TiN(111) peak disappears after the post treatment. The lattice expansion and peak shift are mainly ascribed to the reduction of nitrogen vacancies in films. The magnetism was suppressed in as-prepared sample due to the pinning effect of the nitrogen vacancies at defect sites or interface. The magnetism can be activated by the plasma implantation along with nitrogen vacancies reduce. The decrease of nitrogen vacancies leads to the enhancement of ferromagnetism. 展开更多
关键词 Epitaxial growth Magnetic materials Thin films Solar energy materials
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《电磁铁》教学设计
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作者 王鹏林 《辽宁教育》 北大核心 1994年第Z1期94-95,共2页
教学目的要求:①指导学生认识电磁铁的构造、性质和用途。②培养学生的实验能力。 教学重点:电磁铁的性质。教学难点;电磁铁的磁极、磁力可变与什么因素有关。 教具准备:电池、大铁钉、漆包线、指南针、大头针等。(够10个实验小组用) ... 教学目的要求:①指导学生认识电磁铁的构造、性质和用途。②培养学生的实验能力。 教学重点:电磁铁的性质。教学难点;电磁铁的磁极、磁力可变与什么因素有关。 教具准备:电池、大铁钉、漆包线、指南针、大头针等。(够10个实验小组用) 教学过程: (一)复习提问:磁铁有哪些性质? 展开更多
关键词 《电磁铁》 教学设计 大头针 极方向 生磁性 南极 实验能力 教学目的 制做方法 性质和用途
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我这样组织《电磁铁》一课的教学
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作者 吕方锦 《实验教学与仪器》 1997年第4期25-26,共2页
关键词 《电磁铁》 大头针 电磁起重机 通电流 对比观察 生磁性 实验 永久磁铁 工作原理及应用 电教手段
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闪光灯
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作者 赵云 《中小学实验与装备》 1999年第5期31-31,共1页
关键词 电磁铁 螺丝钉 生磁性 导体 湖北省钟祥 实验材料 灯电源 实验步骤 弹簧 电灯泡
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Complete spontaneous regression of giant focal nodular hyperplasia of the liver: Magnetic resonance imaging evaluation with hepatobiliary contrast media 被引量:7
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作者 Giuseppe Mamone Settimo Caruso +1 位作者 Kelvin Cortis Roberto Miraglia 《World Journal of Gastroenterology》 SCIE CAS 2016年第47期10461-10464,共4页
Focal nodular hyperplasia(FNH) of the liver is a benign lesion occurring in 0.6%-3% of the general population that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Most lesions... Focal nodular hyperplasia(FNH) of the liver is a benign lesion occurring in 0.6%-3% of the general population that probably reflects a local hyperplastic response of hepatocytes to a vascular abnormality. Most lesions are diagnosed incidentally and the natural history of the disease remains largely unknown. It has been shown that most FNH remain stable, or even regress, over a long follow-up period. We present a patient with FNH of the liver who was followed up for 7 years. A 26-yearold woman with a 5-year history of oral contraceptive use was referred to our hospital in February 2005 for further examination of a liver tumour. The diagnosis of FNH was made using magnetic resonance(MR) imaging with hepatospecific contrast media; this technique allows a correct diagnosis, in particular distinguishing FNH from hepatic adenoma, avoiding an invasive procedure such as the lesion biopsy. After 7-year from the diagnosis, we observed the complete spontaneous regression of the lesion by enhanced MR scanning. In this patient, discontinuation of oral contraceptive use and two childbirths may have influenced the natural history of FNH. To our knowledge, in the English literature there is no report illustrating a complete regression of giant FNH but only studies of decreasing in size. The present case suggests that a young patient with giant FNH should be managed conservatively rather than by resection, because FNH has the potential for spontaneous regression. 展开更多
关键词 Focal nodular hyperplasia Regression Magnetic resonance Oral contraceptives PREGNANCY
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EFFECTS OF VITAMIN D RECEPTOR GENE POLYMORPHISMS ON SUSCEPTIBILITY TO TYPE 1 DIABETES MELLITUS 被引量:8
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作者 Xin-hua Xiao Zhe-long Liu +4 位作者 Heng Wang Qi Sun Wen-hui Li Guo-hua Yang Qiu-ying Liu 《Chinese Medical Sciences Journal》 CAS CSCD 2006年第2期95-98,共4页
Objective To investigate the influence of vitamin D receptor (VDR) gene polymorphisms on susceptibility to type 1 diabetes mellitus (T1DM) in the Chinese Han population. Method One hundred and thirty-six Chinese ... Objective To investigate the influence of vitamin D receptor (VDR) gene polymorphisms on susceptibility to type 1 diabetes mellitus (T1DM) in the Chinese Han population. Method One hundred and thirty-six Chinese Han people, including 54 T1DM patients and 82 unrelated healthy subjects as control were genotyped by polymerase chain reaction-restriction fragment length polymorphism for three restriction sites in the VDR gene, which were ApaI, TaqI, and BamL Results The frequency of B allele of BsmI site in VDR gene was significantly higher in T1DM patients than in healthy subjects ( P = 0. 033 ) while no difference was found between the two groups in the distribution of ApaI and TaqI polymorphisms. Conclusion The BsmI polymorphism of VDR gene may be associated with the susceptibihty to T1DM in the Chinese Han population of Beijing. 展开更多
关键词 type 1 diabetes mellitus vitamin D receptor gene polymorphism
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Role of acoustic interface layer during high intensity focused ultrasound therapeutics 被引量:1
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作者 Li Quanyi Fu Liyuan Qin Yan Li Faqi Wang Zhibiao 《Journal of Medical Colleges of PLA(China)》 CAS 2008年第4期223-227,共5页
After interface layer was simulated by the magnetic nano-particles in the egg white phantom, high intensity focused ultrasound (HIFU) at the same dosage was introduced to radiate the phantom in different depths to b... After interface layer was simulated by the magnetic nano-particles in the egg white phantom, high intensity focused ultrasound (HIFU) at the same dosage was introduced to radiate the phantom in different depths to blow the acoustic interface layer to mimic "point" exposure. The results showed that the volumes of biological focal region (BFR) were enlarged when the acoustic focal region (AFR) is close with interface layer. This meant that the magnetic nano-particles enhanced the therapeutic efficiency of HIFU. When the distance of the AFR from the interface layer was 10 mm, the size and shape of the BFR were similar with those of the control group, but a larger lesion at the interface, which was harmful for treatment, was observed. When the distance of the AFR to the interface layer increased to 30 mm, the size and shape of the BFR were also similar to those of the control group. When the thickness of the interface layer diminished, the utility of enhancement decreased. Continuous increase of the safe area for treatment and decrease of the utility of enhancement were observed along with the abatement of the thickness of the interface layer 展开更多
关键词 Magnetic nano-particles Interface layer Biological focal region High intensity focused ultrasound
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Application of New Type BP Neural Networks for Magnetic Measurement 被引量:1
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作者 张旭 Che Rensheng +1 位作者 Kinouchi Y Luo Xiaochuan 《High Technology Letters》 EI CAS 2002年第2期83-86,共4页
Magnetic measurement is a typical inverse problem in Biomedical field. In this kind of problem we always need to locate the positions and moments of one or more magnetic dipoles. Although using the traditional methods... Magnetic measurement is a typical inverse problem in Biomedical field. In this kind of problem we always need to locate the positions and moments of one or more magnetic dipoles. Although using the traditional methods to solve this kind of inverse problem has all kinds of shortcomings, BPNN (Back Propagation Neural Networks) method can be used to solve this typical inverse problem fast enough for real time measurement. In the traditional BPNN method, gradient descent search method is performed for error propagation. In this paper the authors propose a new algorithm that Newton method is performed for error propagation. For the cost function is highly nonconvex in the magnetic measurement problem, the new kind of BPNN can get convergent results quickly and precisely. A simulation result for this method is also presented. 展开更多
关键词 magnetic measurement BP neural network gradient method Newton Gauss method
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Characterization of Mediterranean Magnetotactic Bacteria 被引量:2
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作者 Lefevre Christopher Bemadac Alain +7 位作者 Pradel Nathalie WU Longfei Yu-Zhang Kui XIAO Tian Yonnet Jean-Paul Lebouc Afef SONG Tao Fukumori Yoshihiro 《Journal of Ocean University of China》 SCIE CAS 2007年第4期355-359,共5页
Magnetotactic bacteria are a diverse group of motile prokaryotes that are ubiquitous in aquatic habitats and cosmopolitan in distribution. In this study, we collected magnetotactic bacteria from the Mediterranean Sea.... Magnetotactic bacteria are a diverse group of motile prokaryotes that are ubiquitous in aquatic habitats and cosmopolitan in distribution. In this study, we collected magnetotactic bacteria from the Mediterranean Sea. A remarkable diversity of morphotypes was observed, including multicellular types that seemed to differ from those previously found in North and South America. Another interesting organism was one with magnetosomes arranged in a six-stranded bundle which occupied one third of the cell width. The magnetosome bundle was evident even under optic microscopy. These cells were connected together and swam as a linear entire unit. Magnetosomes did not always align up to form a straight linear chain. A chain composed of rectangle magnetosomes bent at a posi- tion with an oval crystal. High resolution transmission electron microscopy analysis of the crystal at the pivotal position suggested uncompleted formation of the crystal. This is the first report of Mediterranean magnetotactic bacteria, which should be useful for studies of biogeochemical cycling and geohistory of the Mediterranean Sea. 展开更多
关键词 Magnetotactic bacteria Mediterranean Sea GEOMAGNETISM biogeochemical cycling ECOLOGY magnetosome crystals
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Biosorption Equilibrium and Kinetics of Au(Ⅲ) and Cu(Ⅱ) on Magnetotactic Bacteria 被引量:6
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作者 宋慧平 李鑫钢 +3 位作者 孙津生 尹晓红 王艳红 武振华 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2007年第6期847-854,共8页
Magnetotactic bacteria (MTB) as biosorbents for the adsorption of Au(Ⅲ) and Cu(Ⅱ) ions from aqueous solution have been investigated. The optimum adsorption conditions for both metal ions were the initial pH sc... Magnetotactic bacteria (MTB) as biosorbents for the adsorption of Au(Ⅲ) and Cu(Ⅱ) ions from aqueous solution have been investigated. The optimum adsorption conditions for both metal ions were the initial pH scope of 1-5.5 for Au(Ⅲ) and 2.0-4.5 for Cu(Ⅱ), room temperature, biomass concentration of 10.0g.L^-1 and sorotion du-ration more than 10 min. When the initial metal concentration were within 500mg.L^-1, the maximum biosorption capacity of 1.0g of MTB (dry mass basis) for Au(Ⅲ) and Cu(Ⅱ) were calculated as 505.2mg of Au(Ⅲ) and 493.1mg of.Cu(Ⅱ) by Langmuir model in single system, respectively. The isotherm equilibrium of Au(Ⅲ) and Cu(Ⅱ) ions in the Au-Cu binary system reflected a unique phenomenon that the adsorption of Au(Ⅲ) was rein-forced and that of Cu(Ⅱ) prohibited, compared respectively-with their performances in the single metal system.When the,concentration of-Au(Ⅲ) and Cu(Ⅱ). were below 80mg.L^-1, the waste waterafter MTB treating, wasbelow 1.0mg.L^-1, which is in conformity with Environmental Performance Standards (EPS) of Canada. Besides, all the kinetic data were fitted well to the pseudo second-order kinetic model with a high correlation coefficient (R^2〉0.999). 展开更多
关键词 magnetotactic bacteria selective adsorption adsorption equilibrium adsorption kinetics Au(Ⅲ)
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Synthesis and biochemical properties of fluorescent/magnetic bifunctional starch particles 被引量:1
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作者 王凤华 刘俊 +6 位作者 唐冬英 薛昌刚 肖苏尧 郑元青 童春义 王玲玲 刘选明 《Journal of Central South University》 SCIE EI CAS 2010年第2期211-217,共7页
Magnetic starch particles (MSPs) were synthesized in water-in-oil mieroemulsion at room temperature. MSPs were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectrometry (FTI... Magnetic starch particles (MSPs) were synthesized in water-in-oil mieroemulsion at room temperature. MSPs were characterized by transmission electron microscopy (TEM), Fourier transform infrared spectrometry (FTIR), zeta potential system, thermogravimetric analysis (TGA) and vibrating sample magnetometry (VSM). The average diameter of the MSPs was 220 nm, dispersed with well-proportioned size and magnetic resonance, the saturation magnetization was 3.64 A.mR/kg. MSP was coated with poly-L-lysine (PLL), and then the surface of PLL-MSP was combined with fluorescein isothiocynate (FITC). Results show that fluorescent/magnetic starch particles (FMSPs) are of stable photo-bleaching capability compared with free FITC, with low bio-toxicity and certain function of magnetic separation. It is expected that FMSPs are bifimctional nano-materials including fluorescence labelling and magnetic separation. 展开更多
关键词 starch-particles NANO-MATERIALS SYNTHESIS fluorescent properties magnetic properties biochemical properties
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Physical and electromagnetic shielding properties of green carbon foam prepared from biomaterials 被引量:2
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作者 Ru-min WANG Ke-zhi LI 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2018年第1期103-113,共11页
100%green carbon foam from the fibrous fruits of Platanus Orientalis-L(Plane)along with the tar oil as binder has been prepared using a powder molding technique.The objective was to develop a porous monolithic carbon ... 100%green carbon foam from the fibrous fruits of Platanus Orientalis-L(Plane)along with the tar oil as binder has been prepared using a powder molding technique.The objective was to develop a porous monolithic carbon from biomaterials with a considerable strength necessary for various physical,thermal and electromagnetic shielding applications.Fast carbonization was carried out at1000°C under the cover of Plane tree pyrolyzed seeds without using any external protective gas.For comparative analysis,some samples were mixed with5%(mass fraction)iron chloride during the molding process.Iron chloride being a graphitization catalyst and activating agent helped in increasing the specific surface area from88to294m2/g with a25%decrease in flexural strength.Thermal stability was improved due to the incorporation of more graphitic phases in the sample resulting in a little higher thermal conductivity from0.22to0.67W/(m·K).The catalytic carbon foam exhibited shielding effectiveness of more than20dB over the X-band frequency.Absorption was dominant with only8.26%?10.33%reflectance,indicating an absorption dominant shielding mechanism.The new material is quite suitable for high temperature thermal insulation being lightweight,highly porous with interconnected porous morphology most of which is preserved from the original biomaterial. 展开更多
关键词 carbon foam BIOMASS PYROLYSIS powder molding electromagnetic properties
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Haptic Interface with Magnetic Field Sensitive Elastomer 被引量:1
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作者 Takehito Kikuchi Yasunobu Masuda Kento Amano Tetsu Mitsumata Suguru Ohori 《Journal of Mechanics Engineering and Automation》 2013年第3期146-151,共6页
Sense of touch is one of the important information from environment for human to live in daily life. Haptic interface is a hot topic in virtual reality but almost all of the devices focus on fingers and hands as targe... Sense of touch is one of the important information from environment for human to live in daily life. Haptic interface is a hot topic in virtual reality but almost all of the devices focus on fingers and hands as targets. In this paper, we focus on the foot haptic device with magnetic flied sensitive elastomer (MSE). We developed a haptic unit used as a magnetic field generator for MSE and contact point of foot haptic device. MSE samples mixed with 80 wt% carbonyl iron particles were prepared and evaluated with the developed magnet. Experimental results show that the mechanical property of the haptic unit can be modeled with the adjustable friction element. This property has a good advantage for the haptic unit. 展开更多
关键词 Human-machine interface haptic interface planter pressure magnetic field sensitive elastomer functional material.
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Entropy optimization in cubic autocatalysis chemical reactive flow of Williamson fluid subjected to viscous dissipation and uniform magnetic field 被引量:1
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作者 M. IJAZ KHAN Sania JAVED +2 位作者 Tasawar HAYAT M. WAQAS Ahmed ALSAEDI 《Journal of Central South University》 SCIE EI CAS CSCD 2019年第5期1218-1232,共15页
This research elaborates magnetohydrodynamics (MHD) impact on non-Newtonian (Williamson) fluid flow by stretchable rotating disks.Both disks are rotating with different angular velocities and different stretching rate... This research elaborates magnetohydrodynamics (MHD) impact on non-Newtonian (Williamson) fluid flow by stretchable rotating disks.Both disks are rotating with different angular velocities and different stretching rates.Viscous dissipation aspect is considered for energy expression formulation.Entropy generation analysis is described via implementation of thermodynamic second law.Chemical processes (heterogeneous and homogeneous) subjected to entropy generation are introduced first time in literature.Boundary-layer approach is employed for modeling.Apposite variables are introduced for non-dimensionalization of governing systems.Homotopy procedure yields convergence of solutions subjected to computations of highly nonlinear expressions.The significant characteristics of sundry factors against thermal,velocity and solutal fields are described graphically.Besides,tabular results are addressed for engineering quantities (skin-friction coefficient,Nusselt number).The outcomes certify an increment in temperature distribution for Weissenberg (We) and Eckert (Ec) numbers. 展开更多
关键词 entropy generation viscous dissipation Williamson fluid uniform magnetic felid quartic autocatalysis chemical reaction
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Some New Derivatives of 3H-benzo[b]Furo[3,2-f]- Benzimidazole with Expected Biological Activity
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作者 Mamuka Maisuradze Nana Gaxokidze Sofio Tsqvitaia 《Journal of Chemistry and Chemical Engineering》 2012年第5期484-488,共5页
On the base of benzimidazole and benzofuran containing heterocyclic system, several derivatives with expected biological activity were synthesized. 2,3-diaminodibenzofuran was the primary substance. Adding various cyc... On the base of benzimidazole and benzofuran containing heterocyclic system, several derivatives with expected biological activity were synthesized. 2,3-diaminodibenzofuran was the primary substance. Adding various cyclic agents, 2-phenil was got, 2-(o-chlorophenil), 2-(o-oxyphenil), 2-chlorometyl- and 2-hydroximethyl-3H-benzo[b[furo(3,2-f] benzimidazoles. The aforementioned substances were characterized by IR and NMR spectroscopy. 展开更多
关键词 2 3-Diaminodibenzofuran 2-phenil-3H-benzo[b]furo[3 2-f] benzimidazole 2-(o-chlorophenil)-3H-benzo[b]furo[3 2-f] benzimidazole 2-(o-oxyphenil)-3H-benzo[b]furo[3 2-f] benzimidazole 2-chloromethil-3H-benzo[b]furo[3 2-q benzimidazole 2-hydroxymethil-3H-benzo[b]furo[3 2-f] benzimidazoles.
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Growth and differentiation of neural stem cells with superparamagnetic iron oxides labeling in vitro
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作者 王爽 谢鹏 +5 位作者 牟君 赵裕光 贾延劼 吕发金 罗天友 方维东 《Journal of Medical Colleges of PLA(China)》 CAS 2005年第5期273-275,共3页
Objective: To study the growth and differentiation of superparamagnetie iron oxides(SPIOs) labeled neural stem cells (NSCs). Methods: After NSCs were cultured and subcuhured from newborn rat brain, they were mag... Objective: To study the growth and differentiation of superparamagnetie iron oxides(SPIOs) labeled neural stem cells (NSCs). Methods: After NSCs were cultured and subcuhured from newborn rat brain, they were magnetically labeled with ferumoxides (a kind of SPIOs ). Growth, differentiation and other biology properties of the cells were investigated with immunocytochemistry, transmission electron microscopy (TEM) and Prussian blue staining. Results: Nestin positive cells were found in the culture and offspring clones. NSCs could be differentiated into positive GFAP and NF200 cells in serum culture. When NSCs incubated with ferumoxides, the iron particles were seen in intracellular as well as in offspring clones. With the increase in concentration of ferumoxides (5.6-11.2/μg/ml), ferumoxides showed no significant difference effects on the growth and differentiation of NSCs. When the concentration of ferumoxides exceeded 22.4μg/ml ,there was significant difference(P〈0.05). Conclusion: We successfully label NSCs with ferumoxides,it is useful for tracking of magnetic labeled NSCs in vivo with MRI. 展开更多
关键词 neural stem cells superparamagnetic iron oxides magnetically labeled cells
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A case of gas gangrene in an immunosuppressed Crohn's patient 被引量:1
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作者 Natalie Kiel Vincent Ho Andrew Pascoe 《World Journal of Gastroenterology》 SCIE CAS CSCD 2011年第33期3856-3858,共3页
Clostridium septicum(C.septicum)gas gangrene is well documented in the literature,typically in the setting of trauma or immunosuppression.In this paper,we report a unique case of spontaneous clostridial myonecrosis in... Clostridium septicum(C.septicum)gas gangrene is well documented in the literature,typically in the setting of trauma or immunosuppression.In this paper,we report a unique case of spontaneous clostridial myonecrosis in a patient with Crohn's disease and sulfasalazineinduced neutropenia.The patient presented with left thigh pain,vomiting and diarrhea.Blood tests demonstrated a profound neutropenia,and magnetic resonance imaging of the thigh confirmed extensive myonecrosis.The patient underwent emergency hip disarticulation,followed by hemicolectomy.C.septicum was cultured from the blood.Following completion of antibiotic therapy,the patient developed myonecrosis of the right pectoral muscle necessitating further debridement,and remains on lifelong prophylactic antibiotic therapy. 展开更多
关键词 Crohn's disease Inflammatory bowel disease SULFASALAZINE NEUTROPENIA Clostridium septicum
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The Preparation and Biocompatibility Study on Fe_2O_3 Magnetic Nanoparticles Used in Tumor Hyperthermia
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作者 YAN Shi-yan ZHANG Dong-sheng +5 位作者 GU Ning DING An-wei SHI Da-ren WANG Zi-yu DU Yi-qun YU Bao-hua 《Chinese Journal of Biomedical Engineering(English Edition)》 2007年第3期101-110,共10页
Objective:To evaluate the in vitro and in vivo toxicity of self-prepared nanosized Fe2O3, which has the potential implication in tumor hyperthermia. Methods: Fe2O3 nanoparticles were prepared by improving co-precipi... Objective:To evaluate the in vitro and in vivo toxicity of self-prepared nanosized Fe2O3, which has the potential implication in tumor hyperthermia. Methods: Fe2O3 nanoparticles were prepared by improving co-precipitation, which characterization was detected by TEM, XRD, CMIAS, EDS. MTT assay was used to evaluate the in vitro cytotoxicity test; hemolytic test was carried out to estimate whether it has blood toxicity; Fe2O3 suspended in sterile 0.9% NaCl was intraperitoneally injected into Kumning mouse to calculate the LD50 ; micronucleus (MN) were reckoned to identify whether it is genotoxic. Results:The nanoparticles are brown spherical particles with diameter ranging from 8 to 15 nm, which have good decentralization and stability. The experiments also showed that the toxicity of the material on mouse fibroblast (L-929) cell lines was 0 - 1 degree ; it has no hemolysis activity; LD50 arrived at 5.45 g/kg^-1 after intraperitoneal injection of 1 ml suspension; micronucleus test showed that it has no genotoxic effects either. Conclusion: The results showed that the Fe2O3 nanoparticles are prepared successfully, the self-prepared nanosized Fe2O3 is a kind of high biocompatibility materials and perhaps it is suitable for further application in tumor hyperthermia. 展开更多
关键词 FE2O3 PREPARATION BIOCOMPATIBILITY HYPERTHERMIA
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