The therapeutic replacement of diseased tubular tissue is hindered by the availability and suitability of current donor, autologous and synthetically derived protheses. Artificially created, tissue engineered, constru...The therapeutic replacement of diseased tubular tissue is hindered by the availability and suitability of current donor, autologous and synthetically derived protheses. Artificially created, tissue engineered, constructs have the potential to alleviate these concerns with reduced autoimmune response, high anatomical accuracy, long-term patency and growth potential. The advent of 3D bioprinting technology has further supplemented the technological toolbox, opening up new biofabrication research opportunities and expanding the therapeutic potential of the field. In this review, we highlight the challenges facing those seeking to create artificial tubular tissue with its associated complex macro- and microscopic architecture. Current biofabrication approaches, including 3D printing techniques, are reviewed and future directions suggested.展开更多
Three-dimensional （3D） bioprinting is a computer-assisted technology which precisely controls spatial position of biomaterials, growth factors and living cells, offering unprecedented possibility to bridge the gap b...Three-dimensional （3D） bioprinting is a computer-assisted technology which precisely controls spatial position of biomaterials, growth factors and living cells, offering unprecedented possibility to bridge the gap between structurally mimic tissue constructs and functional tissues or organoids. We briefly focus on diverse bioinks used in the recent progresses of biofabrication and 3D bioprinting of various tissue architectures including blood vessel, bone, cartilage, skin, heart, liver and nerve systems. This paper provides readers a guideline with the conjunction between bioinks and the targeted tissue or organ types in structuration and final functionalization of these tissue analogues. The challenges and perspectives in 3D bioprinting field are also illustrated.展开更多
The marine ecological cultural heritage demonstrates tiie long-standing wisdom of human marine ecological culture. Its effective protection and inheritance is a continuation of the traditional marine ecological lifest...The marine ecological cultural heritage demonstrates tiie long-standing wisdom of human marine ecological culture. Its effective protection and inheritance is a continuation of the traditional marine ecological lifestyle, and is also an important impetus to the current construction of marine ecological civilization in China. The paf ticipation and interaction of cultural origins should be pfomoted, system protection management systems should be continuously improved, policies, reguktions and supporting mechanisms should be improved, and scientific evaluation mechanisms should be established, gradually realizing innovative development.展开更多
Using Shanghai as the background, the paper demonstrates the rise and development of Shanghai independent designer brands. It analyzes the survival situation of these independent designer brands and points out the dev...Using Shanghai as the background, the paper demonstrates the rise and development of Shanghai independent designer brands. It analyzes the survival situation of these independent designer brands and points out the development attributions and problems existed, aiming to find the future development path and fitting marketing strategy for those brands.展开更多
基金We acknowledge the funding support from UK Engineering and Physical Sciences Research Council （EPSRC） on the Doctoral Prize Fellowship （Grant No. EP/N509760/1） for IH and the EngD studentship （Grant No. EP/L015595/1） for JL. JZS is funded by Overseas Scholarship Council and Ministry of Education in China. We also acknowledge the funding support from China-UK Research and Innovation Partnership Fund： Newton Fund Ph.D. placement programme. We thank the National Natural Science Foundation of China （No. 21534007）, and the Beijing Municipal Science ＆ Technology Commission for their financial support.
文摘The therapeutic replacement of diseased tubular tissue is hindered by the availability and suitability of current donor, autologous and synthetically derived protheses. Artificially created, tissue engineered, constructs have the potential to alleviate these concerns with reduced autoimmune response, high anatomical accuracy, long-term patency and growth potential. The advent of 3D bioprinting technology has further supplemented the technological toolbox, opening up new biofabrication research opportunities and expanding the therapeutic potential of the field. In this review, we highlight the challenges facing those seeking to create artificial tubular tissue with its associated complex macro- and microscopic architecture. Current biofabrication approaches, including 3D printing techniques, are reviewed and future directions suggested.
基金The authors acknowledge financial support from the National Natural Science Foundation of China （Project No. 21703253, 21774132, 21644007） and the Talent Fund of the Recruit- ment Program of Global Youth Experts.
文摘Three-dimensional （3D） bioprinting is a computer-assisted technology which precisely controls spatial position of biomaterials, growth factors and living cells, offering unprecedented possibility to bridge the gap between structurally mimic tissue constructs and functional tissues or organoids. We briefly focus on diverse bioinks used in the recent progresses of biofabrication and 3D bioprinting of various tissue architectures including blood vessel, bone, cartilage, skin, heart, liver and nerve systems. This paper provides readers a guideline with the conjunction between bioinks and the targeted tissue or organ types in structuration and final functionalization of these tissue analogues. The challenges and perspectives in 3D bioprinting field are also illustrated.
基金Sponsored by Post-Doctoral Applied Research Project of Qingdao(861605040100)
文摘The marine ecological cultural heritage demonstrates tiie long-standing wisdom of human marine ecological culture. Its effective protection and inheritance is a continuation of the traditional marine ecological lifestyle, and is also an important impetus to the current construction of marine ecological civilization in China. The paf ticipation and interaction of cultural origins should be pfomoted, system protection management systems should be continuously improved, policies, reguktions and supporting mechanisms should be improved, and scientific evaluation mechanisms should be established, gradually realizing innovative development.
文摘Using Shanghai as the background, the paper demonstrates the rise and development of Shanghai independent designer brands. It analyzes the survival situation of these independent designer brands and points out the development attributions and problems existed, aiming to find the future development path and fitting marketing strategy for those brands.
