Panorama field geological image is an important form of displaying field geology information with high resolution.Taking an example for Xingcheng,the authors studied the use of panorama field geological images based o...Panorama field geological image is an important form of displaying field geology information with high resolution.Taking an example for Xingcheng,the authors studied the use of panorama field geological images based on the Flex for rich client display technology,application of Google maps API for Flash,and discussed construction method for field geological panoramic information system which created the rich client Internet application program.The results indicate that using Google maps API to mark position and route of panoramic image collection point can be fully integrated field geological information and map information.It can provide visual field geological information for users.This program is characterized by quick execution speed,strong interaction and rich function,which promotes the users'experience effectively.展开更多
Transcriptome reconstruction is an important application of RNA-Seq,providing critical information for further analysis of transcriptome.Although RNA-Seq offers the potential to identify the whole picture of transcrip...Transcriptome reconstruction is an important application of RNA-Seq,providing critical information for further analysis of transcriptome.Although RNA-Seq offers the potential to identify the whole picture of transcriptome,it still presents special challenges.To handle these difficulties and reconstruct transcriptome as completely as possible,current computational approaches mainly employ two strategies:de novo assembly and genome-guided assembly.In order to find the similarities and differences between them,we firstly chose five representative assemblers belonging to the two classes respectively,and then investigated and compared their algorithm features in theory and real performances in practice.We found that all the methods can be reduced to graph reduction problems,yet they have different conceptual and practical implementations,thus each assembly method has its specific advantages and disadvantages,performing worse than others in certain aspects while outperforming others in anther aspects at the same time.Finally we merged assemblies of the five assemblers and obtained a much better assembly.Additionally we evaluated an assembler using genome-guided de novo assembly approach,and achieved good performance.Based on these results,we suggest that to obtain a comprehensive set of recovered transcripts,it is better to use a combination of de novo assembly and genome-guided assembly.展开更多
文摘Panorama field geological image is an important form of displaying field geology information with high resolution.Taking an example for Xingcheng,the authors studied the use of panorama field geological images based on the Flex for rich client display technology,application of Google maps API for Flash,and discussed construction method for field geological panoramic information system which created the rich client Internet application program.The results indicate that using Google maps API to mark position and route of panoramic image collection point can be fully integrated field geological information and map information.It can provide visual field geological information for users.This program is characterized by quick execution speed,strong interaction and rich function,which promotes the users'experience effectively.
基金supported by the National Basic Research Program of China (2010CB945401)the National Natural Science Foundation of China (31240038, 31171264, 31071162, 31000590)the Science and Technology Commission of Shanghai Municipality (11DZ2260300)
文摘Transcriptome reconstruction is an important application of RNA-Seq,providing critical information for further analysis of transcriptome.Although RNA-Seq offers the potential to identify the whole picture of transcriptome,it still presents special challenges.To handle these difficulties and reconstruct transcriptome as completely as possible,current computational approaches mainly employ two strategies:de novo assembly and genome-guided assembly.In order to find the similarities and differences between them,we firstly chose five representative assemblers belonging to the two classes respectively,and then investigated and compared their algorithm features in theory and real performances in practice.We found that all the methods can be reduced to graph reduction problems,yet they have different conceptual and practical implementations,thus each assembly method has its specific advantages and disadvantages,performing worse than others in certain aspects while outperforming others in anther aspects at the same time.Finally we merged assemblies of the five assemblers and obtained a much better assembly.Additionally we evaluated an assembler using genome-guided de novo assembly approach,and achieved good performance.Based on these results,we suggest that to obtain a comprehensive set of recovered transcripts,it is better to use a combination of de novo assembly and genome-guided assembly.
