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灵活建系 妙用基底
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作者 傅鲜兵 《中学教研(数学版)》 2016年第4期1-2,共2页
向量是近代数学中重要和基本的数学概念之一,它是沟通代数、几何与三角函数的一种工具,有着丰富的实际背景.在高中阶段,向量有着举足轻重的作用,并不断在高考中得以体现."建系"与"用基底"是用向量解决几何问题的2个妙招.
关键词 向量 建系 用基底
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Enhanced production of leptin in gastric fundic mucosa with Helicobacter pyloriinfection 被引量:9
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作者 YoshitoNishi Hajimelsomoto +7 位作者 ShigeoUotani ChunYangWen SaburoShikuwa KenOhnita YoheiMizuta AkioKawaguchi Kenichirolnoue ShigeruKoimo 《World Journal of Gastroenterology》 SCIE CAS CSCD 2005年第5期695-699,共5页
AIM: To determine the concentrations of leptin in plasma and gastric fundic mucosa in humans, with reference to Helicobacterpylori (Hpylori) infection, and their association with gastric mucosal levels of interleukin ... AIM: To determine the concentrations of leptin in plasma and gastric fundic mucosa in humans, with reference to Helicobacterpylori (Hpylori) infection, and their association with gastric mucosal levels of interleukin (IL)-1β, IL-6 and IL-8, METHODS: Plasma leptin concentrations were determined in 135 outpatients with non-ulcer dyspepsia, consisting of 95 H pylori- infected and 40 uninfected subjects, and 13 patients before and after cure of the infection with anti-H pylori regimen. Using biopsy samples that were endoscopically obtained from the middle corpus along the greater curvature, gastric leptin contents were measured by radioimmunoassay and the mucosal concentrations of IL-Iβ, IL-6 and IL-8 were measured by enzyme linked immunosorbent assay. We also analysed the expression of leptin in the fundic mucosa by reverse transcriptase-polymerase chain reaction (RT-PCR) and immunohistochemistry. RESULTS: The mucosal levels of leptin in the fundic mucosa of H pylori-infected patients were significantly higher than those of uninfected patients. The amount of gastric leptin correlated positively with the mucosal levels of IL-1β and IL-6, but not IL-8. Circulating leptin correlated with body mass index, but not with H pylori status, and there was no change in plasma leptin levels following cure of the infection. Leptin immunoreactive cells were noted in the lower half of the fundic glands, and its expression of messenger ribonucleic acid in the oxyntic mucosa was detected by RT-PCR. CONCLUSION: Leptin production is enhanced in H pylori-infected gastric mucosa. Gastric leptin may be involved in immune and inflammatory response during H pylori infection, through interaction with proinflammatory cytokines. 展开更多
关键词 Helicobacter pylori infection Gastric fundic mucosa LEPTIN
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