The title compound was synthesized from 2,4 difluoro α (1 H 1,2,4 triazol 1 yl) acetophenone by phase transfer catalytic reaction with trimethyl sulfoxonium iodide. Total yield of this improved method was 42%.
Methane sulfonate of copper, cobalt, zinc, lanthanide, praseodymium and neodymium are synthesized and characterized by FTIR and TGA. Methane sulfonates are used as the catalysts in the esterification of chloroacetic a...Methane sulfonate of copper, cobalt, zinc, lanthanide, praseodymium and neodymium are synthesized and characterized by FTIR and TGA. Methane sulfonates are used as the catalysts in the esterification of chloroacetic acid with isopropanol. Catalytic activity of methane sulfonates is studied and compared with other Lewis acids. Under the condition of 1.2/1 molar ratio of isopropanol to chloroacetic acid, 1% catalyst (molar percent of chloroacetic acid), 2.5h reaction time, 80～ 85℃ temperature and benzene as water carrying agent. The experimental results showed that catalytic activity of Lanthanide methane sulfonate was the best, the yield of isopropyl chloroacetate reaches 88.7% . Copper methane sulfonate can be reused for three times without distinct loss of catalytic activity.展开更多
文摘The title compound was synthesized from 2,4 difluoro α (1 H 1,2,4 triazol 1 yl) acetophenone by phase transfer catalytic reaction with trimethyl sulfoxonium iodide. Total yield of this improved method was 42%.
文摘Methane sulfonate of copper, cobalt, zinc, lanthanide, praseodymium and neodymium are synthesized and characterized by FTIR and TGA. Methane sulfonates are used as the catalysts in the esterification of chloroacetic acid with isopropanol. Catalytic activity of methane sulfonates is studied and compared with other Lewis acids. Under the condition of 1.2/1 molar ratio of isopropanol to chloroacetic acid, 1% catalyst (molar percent of chloroacetic acid), 2.5h reaction time, 80～ 85℃ temperature and benzene as water carrying agent. The experimental results showed that catalytic activity of Lanthanide methane sulfonate was the best, the yield of isopropyl chloroacetate reaches 88.7% . Copper methane sulfonate can be reused for three times without distinct loss of catalytic activity.
