肺淋巴上皮瘤样癌是一种罕见的原发性肺癌,与Epstein-Barr病毒(Epstein-Barr virus,EBV)感染密切相关,好发于亚裔、年轻、不吸烟人群。肺癌常见的驱动基因在肺淋巴上皮瘤样癌中发生率低,程序性死亡受体配体1(programmed death ligand 1,...肺淋巴上皮瘤样癌是一种罕见的原发性肺癌,与Epstein-Barr病毒(Epstein-Barr virus,EBV)感染密切相关,好发于亚裔、年轻、不吸烟人群。肺癌常见的驱动基因在肺淋巴上皮瘤样癌中发生率低,程序性死亡受体配体1(programmed death ligand 1,PD-L1)表达多为阳性。肺淋巴上皮瘤样癌多采取以手术为主的综合治疗模式,含铂类的双药化疗是目前晚期肺淋巴上皮瘤样癌最常见的一线化疗方案,随着肿瘤的诊断与治疗进入精准时代,靶向治疗、免疫治疗可能成为肺淋巴上皮瘤样癌治疗新的突破口。文章综述了肺淋巴上皮瘤样癌最新的诊断与治疗进展,以期为临床医师及研究学者提供参考。展开更多
子宫炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor of the Uterus,UIMT)为子宫间质中度恶性肿瘤,其病因尚未明确,临床上相对罕见。UIMT的临床表现并不特异,诊断主要依靠病理与免疫组化检查。UIMT主要的治疗手段包括手术切除...子宫炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor of the Uterus,UIMT)为子宫间质中度恶性肿瘤,其病因尚未明确,临床上相对罕见。UIMT的临床表现并不特异,诊断主要依靠病理与免疫组化检查。UIMT主要的治疗手段包括手术切除或药物治疗,而靶向治疗为未来的重点研究方向。本文旨在综述该病的临床特点、诊断与鉴别诊断、治疗与预后,以提高临床对UIMT的认识。展开更多
炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor, IMT)最常发生于肺脏,发生在肝脏的比较少见,肝脏炎性肌纤维母细胞瘤是一种非常罕见的具有潜在恶性的肿瘤,完全手术切除后的预后较为良好。然而,它缺乏特定的临床症状和独特的...炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor, IMT)最常发生于肺脏,发生在肝脏的比较少见,肝脏炎性肌纤维母细胞瘤是一种非常罕见的具有潜在恶性的肿瘤,完全手术切除后的预后较为良好。然而,它缺乏特定的临床症状和独特的影像学特征。同时,肝脏IMT的罕见性不应降低其在肝脏肿瘤鉴别诊断中的重要性。本文就肝脏炎性肌纤维母细胞瘤(IMT)的临床表现、影像学表现、病理组织学表现、鉴别诊断及诊断治疗策略等方面对其进行全面的阐述以及了解。Inflammatory myofibroblastic tumor (IMT) occurs most often in the lungs, but less commonly in the liver, hepatic inflammatory myofibroblastoma is a very rare potentially malignant tumor, and the prognosis after surgical resection is relatively good. However, it lacks specific clinical symptoms and unique imaging features. At the same time, the rarity of hepatic IMT should not diminish its importance in the differential diagnosis of liver tumors. This article provides a comprehensive introduction and understanding of the clinical manifestations, imaging manifestations, histopathological manifestations, differential diagnosis, and diagnostic and therapeutic strategies of inflammatory myofibroblastoma (IMT) in the liver.展开更多
目的:探讨卵巢甲状腺囊肿的诊断及治疗。方法:汇报1例陕西省人民医院妇科诊治的卵巢甲状腺肿病例,分析其临床资料、影像学检查及治疗。并进行文献复习及总结。结果:卵巢甲状腺肿是一种罕见的卵巢良性畸胎瘤,发病率低,且多为良性肿瘤,极...目的:探讨卵巢甲状腺囊肿的诊断及治疗。方法:汇报1例陕西省人民医院妇科诊治的卵巢甲状腺肿病例,分析其临床资料、影像学检查及治疗。并进行文献复习及总结。结果:卵巢甲状腺肿是一种罕见的卵巢良性畸胎瘤,发病率低,且多为良性肿瘤,极少数可进展成为恶性甲状腺肿,以甲状腺乳头状癌和滤泡癌最为常见,目前主要通过单个病例报道文献了解该疾病,目前治疗方案首选手术治疗,若术后发生恶性甲状腺肿转移,给予辅助甲状腺切除及I131治疗并且经验性给予化学治疗。本例卵巢甲状腺肿病例行腹腔镜双侧附件切除术,术后随访8个月,未见复发或远处转移。结论:卵巢甲状腺肿发病率低,首选手术治疗,治疗方案取决于年龄、生育情况、术中情况、肿瘤性质、全身情况,术后若发生恶性甲状腺肿转移,给予辅助治疗。Objective: To explore the diagnosis and treatment of ovarian thyroid cyst. Methods: A case of ovarian goiter diagnosed and treated by gynecology department of Shaanxi Provincial People’s Hospital was reported. The clinical data, imaging examination and treatment were analyzed. And make the literature review and summary. Results: Struma ovarii is a rare benign teratoma of ovary with a low incidence and mostly benign tumors, and very few of them can progress to malignant struma, the most common of which are papillary carcinoma and follicular carcinoma of thyroid. At present, this disease is mainly understood through single case reports and literatures. At present, surgical treatment is the preferred treatment. If malignant goiter metastasis occurs after surgery, adjuvant thyroidectomy and I131 therapy are given and chemotherapy is empirically administered. This case of struma ovarii underwent laparoscopic bilateral adnexectomy and was followed up for 8 months. No recurrence or distant metastasis was observed. Conclusion: The incidence of ovarian goiter is low, the first choice of surgical treatment, treatment depends on age, fertility, intraoperative conditions, tumor nature and systemic conditions. If malignant goiter metastasis occurs after surgery, adjuvant treatment should be given.展开更多
文摘肺淋巴上皮瘤样癌是一种罕见的原发性肺癌,与Epstein-Barr病毒(Epstein-Barr virus,EBV)感染密切相关,好发于亚裔、年轻、不吸烟人群。肺癌常见的驱动基因在肺淋巴上皮瘤样癌中发生率低,程序性死亡受体配体1(programmed death ligand 1,PD-L1)表达多为阳性。肺淋巴上皮瘤样癌多采取以手术为主的综合治疗模式,含铂类的双药化疗是目前晚期肺淋巴上皮瘤样癌最常见的一线化疗方案,随着肿瘤的诊断与治疗进入精准时代,靶向治疗、免疫治疗可能成为肺淋巴上皮瘤样癌治疗新的突破口。文章综述了肺淋巴上皮瘤样癌最新的诊断与治疗进展,以期为临床医师及研究学者提供参考。
文摘子宫炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor of the Uterus,UIMT)为子宫间质中度恶性肿瘤,其病因尚未明确,临床上相对罕见。UIMT的临床表现并不特异,诊断主要依靠病理与免疫组化检查。UIMT主要的治疗手段包括手术切除或药物治疗,而靶向治疗为未来的重点研究方向。本文旨在综述该病的临床特点、诊断与鉴别诊断、治疗与预后,以提高临床对UIMT的认识。
文摘炎性肌纤维母细胞瘤(Inflammatory Myofibroblastic Tumor, IMT)最常发生于肺脏,发生在肝脏的比较少见,肝脏炎性肌纤维母细胞瘤是一种非常罕见的具有潜在恶性的肿瘤,完全手术切除后的预后较为良好。然而,它缺乏特定的临床症状和独特的影像学特征。同时,肝脏IMT的罕见性不应降低其在肝脏肿瘤鉴别诊断中的重要性。本文就肝脏炎性肌纤维母细胞瘤(IMT)的临床表现、影像学表现、病理组织学表现、鉴别诊断及诊断治疗策略等方面对其进行全面的阐述以及了解。Inflammatory myofibroblastic tumor (IMT) occurs most often in the lungs, but less commonly in the liver, hepatic inflammatory myofibroblastoma is a very rare potentially malignant tumor, and the prognosis after surgical resection is relatively good. However, it lacks specific clinical symptoms and unique imaging features. At the same time, the rarity of hepatic IMT should not diminish its importance in the differential diagnosis of liver tumors. This article provides a comprehensive introduction and understanding of the clinical manifestations, imaging manifestations, histopathological manifestations, differential diagnosis, and diagnostic and therapeutic strategies of inflammatory myofibroblastoma (IMT) in the liver.
文摘目的:探讨卵巢甲状腺囊肿的诊断及治疗。方法:汇报1例陕西省人民医院妇科诊治的卵巢甲状腺肿病例,分析其临床资料、影像学检查及治疗。并进行文献复习及总结。结果:卵巢甲状腺肿是一种罕见的卵巢良性畸胎瘤,发病率低,且多为良性肿瘤,极少数可进展成为恶性甲状腺肿,以甲状腺乳头状癌和滤泡癌最为常见,目前主要通过单个病例报道文献了解该疾病,目前治疗方案首选手术治疗,若术后发生恶性甲状腺肿转移,给予辅助甲状腺切除及I131治疗并且经验性给予化学治疗。本例卵巢甲状腺肿病例行腹腔镜双侧附件切除术,术后随访8个月,未见复发或远处转移。结论:卵巢甲状腺肿发病率低,首选手术治疗,治疗方案取决于年龄、生育情况、术中情况、肿瘤性质、全身情况,术后若发生恶性甲状腺肿转移,给予辅助治疗。Objective: To explore the diagnosis and treatment of ovarian thyroid cyst. Methods: A case of ovarian goiter diagnosed and treated by gynecology department of Shaanxi Provincial People’s Hospital was reported. The clinical data, imaging examination and treatment were analyzed. And make the literature review and summary. Results: Struma ovarii is a rare benign teratoma of ovary with a low incidence and mostly benign tumors, and very few of them can progress to malignant struma, the most common of which are papillary carcinoma and follicular carcinoma of thyroid. At present, this disease is mainly understood through single case reports and literatures. At present, surgical treatment is the preferred treatment. If malignant goiter metastasis occurs after surgery, adjuvant thyroidectomy and I131 therapy are given and chemotherapy is empirically administered. This case of struma ovarii underwent laparoscopic bilateral adnexectomy and was followed up for 8 months. No recurrence or distant metastasis was observed. Conclusion: The incidence of ovarian goiter is low, the first choice of surgical treatment, treatment depends on age, fertility, intraoperative conditions, tumor nature and systemic conditions. If malignant goiter metastasis occurs after surgery, adjuvant treatment should be given.
