目的:观察中药外敷联合电子灸疗、热疗治疗乳腺癌术后上肢水肿的治疗效果。方法:选取2012年1月—2015年12月秦皇岛市中医院肿瘤科门诊及住院的乳腺癌患者60例,随机分为治疗组和对照组,每组30例。对照组给予5%葡萄糖250 m L加丹参注射液2...目的:观察中药外敷联合电子灸疗、热疗治疗乳腺癌术后上肢水肿的治疗效果。方法:选取2012年1月—2015年12月秦皇岛市中医院肿瘤科门诊及住院的乳腺癌患者60例,随机分为治疗组和对照组,每组30例。对照组给予5%葡萄糖250 m L加丹参注射液20 m L静脉滴注,并配合局部肢体功能锻炼,治疗组给予中药局部外敷联合电子灸疗、热疗治疗。结果:治疗组有效率为93.3%,对照组有效率为66.7%,治疗组优于对照组(P<0.05)。结论:中药外敷联合电子灸疗、热疗治疗乳腺癌术后上肢水肿疗效良好。展开更多
AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHO...AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 < 0.01) and gallbladder group (0.9640 ± 0.0387, P = 0.00 < 0.01) had a tendency to enhance the EGFR gene expression in gastric mucosal cells. Such tendency existed in the model group (0.7104 ± 0.0457) but with no signifi cant difference (P = 0.495 > 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.展开更多
Electroencephalogram (EEG)-recorded rhythmicelectrophysiologic activity of brain is synchronoussynthesis of postsynaptic potentials of pyramidalcells and their parietal dendrites of the cerebralcortex.Abnormal changes...Electroencephalogram (EEG)-recorded rhythmicelectrophysiologic activity of brain is synchronoussynthesis of postsynaptic potentials of pyramidalcells and their parietal dendrites of the cerebralcortex.Abnormal changes in EEG and brainelectrical activity mapping (BEAM) appear prior tothat in computed tomography (CT) and nuclearmagnetic resonance (NMR) during the acute stage ofencephalitis,providing a scientific and展开更多
Objective: To observe the effect of electroacupuncture(EA) on cytochrome c oxidase(COX) activity of hippocampal mitochondria in senescence-accelerated mouse prone 8(SAMP8) mice, and to explore the EA mechanism on Alzh...Objective: To observe the effect of electroacupuncture(EA) on cytochrome c oxidase(COX) activity of hippocampal mitochondria in senescence-accelerated mouse prone 8(SAMP8) mice, and to explore the EA mechanism on Alzheimer disease(AD) in improving energy metabolic disorder. Methods: Twelve SAMP8 mice were randomly divided into a model group and an EA group, with six in each group. Six senescence-accelerated mouse resistance 1(SAMR1) mice were prepared as blank group. Mice in the EA group received EA on Baihui(GV 20) and Yongquan(KI 1), once a day for 7 d as a course, altogether 3 courses with one day interval between two courses. Mice in the model group and the blank group were manipulated and fixed as those in the EA group. After interventions, Morris water maze was employed to test spatial learning and memory ability to evaluate EA effect; spectrophotometry was used to detect the activity of hippocampal mitochondria COX. Results: Compared with the blank group, mean escape latencies of the EA group and model group were prolonged significantly in Morris water maze tests(P<0.01), the residue duration in the former platform quadrant significantly decreased(P<0.01). Compared with the model group, mean escape latencies on 1 d, 2 d and 3 d of the EA group were significantly reduced(P<0.05), and those on 4 d and 5 d continued the decreasing tendency(P<0.01), the residue duration on the former platform quadrant was significantly prolonged(P<0.05). The COX activity tests showed that, compared with the blank group, COX activities of the model group and the EA group were significantly decreased(P<0.01); compared with the model group, COX activity of the EA group was significantly elevated(P<0.01). Conclusion: It's plausible that EA improves AD learning and memory ability by increasing mitochondria COX activity, protecting the structure and function, and improving energy metabolism.展开更多
文摘目的:观察中药外敷联合电子灸疗、热疗治疗乳腺癌术后上肢水肿的治疗效果。方法:选取2012年1月—2015年12月秦皇岛市中医院肿瘤科门诊及住院的乳腺癌患者60例,随机分为治疗组和对照组,每组30例。对照组给予5%葡萄糖250 m L加丹参注射液20 m L静脉滴注,并配合局部肢体功能锻炼,治疗组给予中药局部外敷联合电子灸疗、热疗治疗。结果:治疗组有效率为93.3%,对照组有效率为66.7%,治疗组优于对照组(P<0.05)。结论:中药外敷联合电子灸疗、热疗治疗乳腺癌术后上肢水肿疗效良好。
基金Supported by the National Natural Science Foundation of China, No. 90209023 the State 973 Project, No. 2005CB523308
文摘AIM: To investigate the effect of serum derived from rats treated with electroacupuncture at stomach meridian acupoints on the expression of epidermal growth factor receptor (EGFR) gene in gastric mucosal cells. METHODS: The stress-induced gastric mucosal injury in rat model was established by water-immersion and restrained stress methods. 52 rats were randomly divided into: normal group (n = 8), model group (n = 8), model serum group (n = 12), stomach serum group (n = 12), and gallbladder serum group (n = 12). The gastric mucosal cells were separated by pronase-EDTA digestion method and incubated with serum. The EGFR gene expression in gastric mucosal cells was detected by reverse transcription-polymerase chain reaction (RT-PCR) method. RESULTS: Compared with normal group (0.6860 ± 0.0594), the serum derived from rats of the stomach group (1.2272 ± 0.0813, P = 0.00 < 0.01) and gallbladder group (0.9640 ± 0.0387, P = 0.00 < 0.01) had a tendency to enhance the EGFR gene expression in gastric mucosal cells. Such tendency existed in the model group (0.7104 ± 0.0457) but with no signifi cant difference (P = 0.495 > 0.05) and in model serum group (0.8516 ± 0.0409) with an extremely obvious difference (P = 0.001 < 0.01). Furthermore, the EGFR gene expression in stomach serum group was significantly higher than that in gallbladder serum group (P = 0.00 < 0.01). CONCLUSION: The present study shows that serumderived from rats treated with electroacupuncture at stomach meridian acupoints can distinctly increase the EGFR gene expression of gastric mucosal cells. Therefore, there is certain meridian specificity in the serum, which could provide a proof for the TCM theory “particular relation between meridian and internal organ”.
文摘Electroencephalogram (EEG)-recorded rhythmicelectrophysiologic activity of brain is synchronoussynthesis of postsynaptic potentials of pyramidalcells and their parietal dendrites of the cerebralcortex.Abnormal changes in EEG and brainelectrical activity mapping (BEAM) appear prior tothat in computed tomography (CT) and nuclearmagnetic resonance (NMR) during the acute stage ofencephalitis,providing a scientific and
基金supported by National Natural Science Foundation of China (No.30472235)Scientific Science Foundation for the Youth of the Education Department of Sichuan Province (No. 2006B023)
文摘Objective: To observe the effect of electroacupuncture(EA) on cytochrome c oxidase(COX) activity of hippocampal mitochondria in senescence-accelerated mouse prone 8(SAMP8) mice, and to explore the EA mechanism on Alzheimer disease(AD) in improving energy metabolic disorder. Methods: Twelve SAMP8 mice were randomly divided into a model group and an EA group, with six in each group. Six senescence-accelerated mouse resistance 1(SAMR1) mice were prepared as blank group. Mice in the EA group received EA on Baihui(GV 20) and Yongquan(KI 1), once a day for 7 d as a course, altogether 3 courses with one day interval between two courses. Mice in the model group and the blank group were manipulated and fixed as those in the EA group. After interventions, Morris water maze was employed to test spatial learning and memory ability to evaluate EA effect; spectrophotometry was used to detect the activity of hippocampal mitochondria COX. Results: Compared with the blank group, mean escape latencies of the EA group and model group were prolonged significantly in Morris water maze tests(P<0.01), the residue duration in the former platform quadrant significantly decreased(P<0.01). Compared with the model group, mean escape latencies on 1 d, 2 d and 3 d of the EA group were significantly reduced(P<0.05), and those on 4 d and 5 d continued the decreasing tendency(P<0.01), the residue duration on the former platform quadrant was significantly prolonged(P<0.05). The COX activity tests showed that, compared with the blank group, COX activities of the model group and the EA group were significantly decreased(P<0.01); compared with the model group, COX activity of the EA group was significantly elevated(P<0.01). Conclusion: It's plausible that EA improves AD learning and memory ability by increasing mitochondria COX activity, protecting the structure and function, and improving energy metabolism.
