Objective To observe the effect of electroacupuncture (EA) on egg quality of polycystic ovarian syndrome (PCOS) patients, and to explore its mechanism. Methods Two hundred patients who received in vitro fertilizat...Objective To observe the effect of electroacupuncture (EA) on egg quality of polycystic ovarian syndrome (PCOS) patients, and to explore its mechanism. Methods Two hundred patients who received in vitro fertilization-embryo transfer (IVF-ET) were divided into an EA group (102 cases) and a control group (98 cases) according to random number table. All the patients in the two groups were given Diane-35 and gonadotropin-releasing hormone agonist (GnRH-α) for ovarian hyperstimulation. Besides, EA intervention was applied to Shenshu (肾俞 BL 23), Qihai (气海 GV 6), Zusanli (足三里ST 36), Sanyinjiao (三阴交 SP 6), Neiguan (内关 PC 6) and Zigong (子宫 EX-CA1), etc. in the EA group. Then egg quality, final outcome of pregnancy and levels of tumor necrosis factor-α (TNF-α) were compared between the two groups. Results (1) EA intervention significantly improved high quality embryo rate of PCOS patients (P〈0.05), and clinical pregnancy rate was increased by 8.36%; (2) EA intervention significantly reduced the TNF-α levels of follicular fluid (13.61±15.46 vs 34.09±93.53, P〈0.05); (3) TNF-α levels of serum and follicular fluid in the pregnancy group were lower than those of non-pregnancy group [pregnancy group: (53.91±63.32) pg/mL, (14.93±25.37) pg/mL, nonpregnancy group: (76.82 ± 82.96) pg/mL, (25.04 ± 35.79) pg/mL], and the differences were significant (both P〈0.05). Conclusion EA improves egg quality of PCOS patients and increases the clinical pregnancy rate of IVF-ET, the mechanism may be related to TNF-α levels.展开更多
Objective: To assess the clinical efficacy of electroacupuncture for treatment of unstable bladder. Methods: Patients were randomly divided into electroacupuncture and control groups and the curative effects were ev...Objective: To assess the clinical efficacy of electroacupuncture for treatment of unstable bladder. Methods: Patients were randomly divided into electroacupuncture and control groups and the curative effects were evaluated according to improvement in clinical symptom and quality of life scores after treatment. Results: The observation indices were significantly lower after than before treatment in both groups (P〈0.05). There was no significant difference in clinical symptom score between the two groups (P〉0.05). Quality of life score was significantly decreased in the electroacupuncture group as compared with that in the manipulation group (P〈0.05). Conclusion: Both treatments improve voiding difficulty. The degree of satisfaction to quality of life is larger in the electroacupuncture group than in the manipulation group. Clinical symptom score tends to be lower in the electroacupuncture group than in the manipulation group.展开更多
Objective: To observe the clinical effect of electroacupuncture (EA) at four sacral points on overactive bladder syndrome. Methods: A total of 120 female patients with overactive bladder syndrome were allocated to...Objective: To observe the clinical effect of electroacupuncture (EA) at four sacral points on overactive bladder syndrome. Methods: A total of 120 female patients with overactive bladder syndrome were allocated to a treatment group of 80 cases and a control group of 40 cases on a voluntary basis. The patients in the treatment group received EA at four sacral points, and the treatment was given three times a week for 6 consecutive weeks, while the patients in the control group received oral administration of M-receptor antagonist tolterodine tartrate, which was given 4 mg each time, once a day for 6 consecutive weeks. Then the symptom scores were compared between the two groups before and after treatment. Results: At the end of treatment, the symptom scores showed statistical significant differences in comparing with those before treatment in both groups (both P〈0.02); the symptom score in the treatment group was lower than that in the control group, showing a statistically significant difference (P〈0.05). Conclusion: EA at four sacral points is an effective method for overactive bladder syndrome.展开更多
Objective:To observe the clinical effect of electroacupuncture for ovulatory dysfunctional infertility by ovulation stimulation.Methods:A total of 65 patients were randomly allocated into a treatment group (38 case...Objective:To observe the clinical effect of electroacupuncture for ovulatory dysfunctional infertility by ovulation stimulation.Methods:A total of 65 patients were randomly allocated into a treatment group (38 cases) and a control group (27 cases).Acupuncture plus electric stimulation was employed in the treatment group,whereas oral Clomifene Citrate Tablets in the control group,50 mg per day.Results:After six months (2 sessions) of treatment,the cure rate in the treatment group was 76.3%,versus 48.1% in the control group,showing a significant difference between the two groups (P〈0.05).Conclusion:Electroacupuncture can obtain better cure rate than oral Clomifene Citrate Tablets for infertility via ovulation stimulation.展开更多
Objective: To investigate the curative effect of electroacupuncture on luteinized unruptured follicle syndrome(LUFS) and its mechanism, Methods: Sixty LUFS patients were randomly allocated to treatment (electroac...Objective: To investigate the curative effect of electroacupuncture on luteinized unruptured follicle syndrome(LUFS) and its mechanism, Methods: Sixty LUFS patients were randomly allocated to treatment (electroacupuncture) group and control (hCG) group. The follicular condition and ovarian arterial flow under color Doppler ultrasonogaphy and a change in reproductive endocrine level were observed in the patients before and after treatments. The ovulation rates and pregnancy rates were compared between the two groups, and the mechanism was investigated. Results: Both ovulation rate and pregnancy rate were significantly higher in the treatment group than in the control group (P〈0.01). There was a significant difference in the improvement in ovarian arterial flow between the treatment and control groups (P〈0.01). The improvement in endocrine level was significantly more marked in the treatment group than in the control group(P〈0.01). Conclusion: Electroacupuncture has a good effect on luteinized unrupture follicle syndrome. Its mechanism may be related to the improvement in ovarian arterial blood supply and the regulation of endocrine level.展开更多
基金Supported by the National Natural Science Foundation of China:30973790
文摘Objective To observe the effect of electroacupuncture (EA) on egg quality of polycystic ovarian syndrome (PCOS) patients, and to explore its mechanism. Methods Two hundred patients who received in vitro fertilization-embryo transfer (IVF-ET) were divided into an EA group (102 cases) and a control group (98 cases) according to random number table. All the patients in the two groups were given Diane-35 and gonadotropin-releasing hormone agonist (GnRH-α) for ovarian hyperstimulation. Besides, EA intervention was applied to Shenshu (肾俞 BL 23), Qihai (气海 GV 6), Zusanli (足三里ST 36), Sanyinjiao (三阴交 SP 6), Neiguan (内关 PC 6) and Zigong (子宫 EX-CA1), etc. in the EA group. Then egg quality, final outcome of pregnancy and levels of tumor necrosis factor-α (TNF-α) were compared between the two groups. Results (1) EA intervention significantly improved high quality embryo rate of PCOS patients (P〈0.05), and clinical pregnancy rate was increased by 8.36%; (2) EA intervention significantly reduced the TNF-α levels of follicular fluid (13.61±15.46 vs 34.09±93.53, P〈0.05); (3) TNF-α levels of serum and follicular fluid in the pregnancy group were lower than those of non-pregnancy group [pregnancy group: (53.91±63.32) pg/mL, (14.93±25.37) pg/mL, nonpregnancy group: (76.82 ± 82.96) pg/mL, (25.04 ± 35.79) pg/mL], and the differences were significant (both P〈0.05). Conclusion EA improves egg quality of PCOS patients and increases the clinical pregnancy rate of IVF-ET, the mechanism may be related to TNF-α levels.
文摘Objective: To assess the clinical efficacy of electroacupuncture for treatment of unstable bladder. Methods: Patients were randomly divided into electroacupuncture and control groups and the curative effects were evaluated according to improvement in clinical symptom and quality of life scores after treatment. Results: The observation indices were significantly lower after than before treatment in both groups (P〈0.05). There was no significant difference in clinical symptom score between the two groups (P〉0.05). Quality of life score was significantly decreased in the electroacupuncture group as compared with that in the manipulation group (P〈0.05). Conclusion: Both treatments improve voiding difficulty. The degree of satisfaction to quality of life is larger in the electroacupuncture group than in the manipulation group. Clinical symptom score tends to be lower in the electroacupuncture group than in the manipulation group.
文摘Objective: To observe the clinical effect of electroacupuncture (EA) at four sacral points on overactive bladder syndrome. Methods: A total of 120 female patients with overactive bladder syndrome were allocated to a treatment group of 80 cases and a control group of 40 cases on a voluntary basis. The patients in the treatment group received EA at four sacral points, and the treatment was given three times a week for 6 consecutive weeks, while the patients in the control group received oral administration of M-receptor antagonist tolterodine tartrate, which was given 4 mg each time, once a day for 6 consecutive weeks. Then the symptom scores were compared between the two groups before and after treatment. Results: At the end of treatment, the symptom scores showed statistical significant differences in comparing with those before treatment in both groups (both P〈0.02); the symptom score in the treatment group was lower than that in the control group, showing a statistically significant difference (P〈0.05). Conclusion: EA at four sacral points is an effective method for overactive bladder syndrome.
基金supported by the Department of Traditional Chinese Medicine of Shenzhen Maternal and Child Health Care Hospital
文摘Objective:To observe the clinical effect of electroacupuncture for ovulatory dysfunctional infertility by ovulation stimulation.Methods:A total of 65 patients were randomly allocated into a treatment group (38 cases) and a control group (27 cases).Acupuncture plus electric stimulation was employed in the treatment group,whereas oral Clomifene Citrate Tablets in the control group,50 mg per day.Results:After six months (2 sessions) of treatment,the cure rate in the treatment group was 76.3%,versus 48.1% in the control group,showing a significant difference between the two groups (P〈0.05).Conclusion:Electroacupuncture can obtain better cure rate than oral Clomifene Citrate Tablets for infertility via ovulation stimulation.
文摘Objective: To investigate the curative effect of electroacupuncture on luteinized unruptured follicle syndrome(LUFS) and its mechanism, Methods: Sixty LUFS patients were randomly allocated to treatment (electroacupuncture) group and control (hCG) group. The follicular condition and ovarian arterial flow under color Doppler ultrasonogaphy and a change in reproductive endocrine level were observed in the patients before and after treatments. The ovulation rates and pregnancy rates were compared between the two groups, and the mechanism was investigated. Results: Both ovulation rate and pregnancy rate were significantly higher in the treatment group than in the control group (P〈0.01). There was a significant difference in the improvement in ovarian arterial flow between the treatment and control groups (P〈0.01). The improvement in endocrine level was significantly more marked in the treatment group than in the control group(P〈0.01). Conclusion: Electroacupuncture has a good effect on luteinized unrupture follicle syndrome. Its mechanism may be related to the improvement in ovarian arterial blood supply and the regulation of endocrine level.