In this study, the inhibitory effect of jujuboside A (JuA) on a penicillin sodium (Na-PCN) induced hyperactivity model was investigated. Cortical EEG (electroencephalogram) and the concentration of hippocampal Glutama...In this study, the inhibitory effect of jujuboside A (JuA) on a penicillin sodium (Na-PCN) induced hyperactivity model was investigated. Cortical EEG (electroencephalogram) and the concentration of hippocampal Glutamate (Glu) were monitored simultaneously in vivo as indicators of rat’s excitatory state. Power spectral density (PSD) and gravity frequency of PSD were calculated. JuA (0.05 g/L and 0.1 g/L) inhibited the EEG excitation effect caused by Na-PCN by increasing the power of δ1 and δ2 bands (P<0.01 vs model) and lowering the gravity frequency of PSD (P<0.01 vs model). JuA also remarkably reduced the Glu elevation induced by Na-PCN (P<0.05 vs model). Diazepam also depressed Glu concentration and lowered the gravity frequency, but it showed a different EEG pattern in increased β2-activity (P<0.01 vs model). EEG excitation caused by Na-PCN correlated with Glu elevation during the first hour. Neurophysiological inhibitory effects of JuA and diazepam were more persistent than their Glu inhibitoty effects.展开更多
To meet the authorization administration requirements in a distributedcomputer network environment, this paper extends the role-based access control model with multipleapplication dimensions and establishes a new acce...To meet the authorization administration requirements in a distributedcomputer network environment, this paper extends the role-based access control model with multipleapplication dimensions and establishes a new access control model ED-RBAC(Extended Role Based AccessControl Model) for the distributed environment. We propose an extendable hierarchical authorizationassignment framework and design effective role-registeringi role-applying and role-assigningprotocol with symmetric and asymmetric cryptographic systems. The model can be used to simplifyauthorization administration in a distributed environment with multiple applications.展开更多
The thesis researches the safety infonnation and control system (SICS) design principle and introduces engineering application in CPR1000 nuclear power station in China. The SICS provides sufficient control and moni...The thesis researches the safety infonnation and control system (SICS) design principle and introduces engineering application in CPR1000 nuclear power station in China. The SICS provides sufficient control and monitoring means to bring and maintain the plant in a safe state as a backup of main computerized control mean (MCM), in any plant conditions that are probable during a planed or unplanned unavailability of the MCM. The successful engineering applications of SICS in different digital I&C system platform are introduced in the paper. The thesis gives the research conclusion for new general SICS of digital I&C system.展开更多
基金Project supported by the National Natural Science Foundation ofChina (No. 30170275) and the Key Laboratory for Biomedical En-gineering of the Ministry of Education of China and Science andTechnology Department of Zhejiang Province (No. 011106239)
文摘In this study, the inhibitory effect of jujuboside A (JuA) on a penicillin sodium (Na-PCN) induced hyperactivity model was investigated. Cortical EEG (electroencephalogram) and the concentration of hippocampal Glutamate (Glu) were monitored simultaneously in vivo as indicators of rat’s excitatory state. Power spectral density (PSD) and gravity frequency of PSD were calculated. JuA (0.05 g/L and 0.1 g/L) inhibited the EEG excitation effect caused by Na-PCN by increasing the power of δ1 and δ2 bands (P<0.01 vs model) and lowering the gravity frequency of PSD (P<0.01 vs model). JuA also remarkably reduced the Glu elevation induced by Na-PCN (P<0.05 vs model). Diazepam also depressed Glu concentration and lowered the gravity frequency, but it showed a different EEG pattern in increased β2-activity (P<0.01 vs model). EEG excitation caused by Na-PCN correlated with Glu elevation during the first hour. Neurophysiological inhibitory effects of JuA and diazepam were more persistent than their Glu inhibitoty effects.
文摘To meet the authorization administration requirements in a distributedcomputer network environment, this paper extends the role-based access control model with multipleapplication dimensions and establishes a new access control model ED-RBAC(Extended Role Based AccessControl Model) for the distributed environment. We propose an extendable hierarchical authorizationassignment framework and design effective role-registeringi role-applying and role-assigningprotocol with symmetric and asymmetric cryptographic systems. The model can be used to simplifyauthorization administration in a distributed environment with multiple applications.
文摘The thesis researches the safety infonnation and control system (SICS) design principle and introduces engineering application in CPR1000 nuclear power station in China. The SICS provides sufficient control and monitoring means to bring and maintain the plant in a safe state as a backup of main computerized control mean (MCM), in any plant conditions that are probable during a planed or unplanned unavailability of the MCM. The successful engineering applications of SICS in different digital I&C system platform are introduced in the paper. The thesis gives the research conclusion for new general SICS of digital I&C system.