An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation tech...An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation technique,the frequency tuning curves agree well with the experiment.At a 3.3V supply,the LC-VCO measures a phase noise of -82.2dBc/Hz at a 10kHz frequency offset while dissipating 3.1mA current.The chip size is 0.86mm×0.82mm.展开更多
Simultaneous dimming controlling and data transmission are usually required in a white LED based indoor visible light communication system.However,the diming controlling of LED normally interferes the data transmissio...Simultaneous dimming controlling and data transmission are usually required in a white LED based indoor visible light communication system.However,the diming controlling of LED normally interferes the data transmission due to the modulation nonlinearity of LED.In order to solve this problem,a scheme by separating the LEDs for the functions of dimming control and data transmission respectively is proposed in this paper.In the scheme,the LEDs used for dimming control function are driven by a dc amplified circuit,and the LEDs for data transmission are driven by a digital modulation circuit respectively.In this way,the modulation distortion to the data signal caused by the modulation nonlinearity can be avoided even if the dimming is at high level dc driven current.The proof-of-concept experiment of a 2.5Mbit/s visible light communication system demonstrates that the dimming controlling and data transmission can be realized simultaneously in a simple way,and the data transmission is not affected by the dimming controlling function.Compared to previous methods,the scheme in this paper is simpler and cost effective,and makes sense when high rate data is transmitted in a visible light communication system.展开更多
Along with the completion of HGP （human genome project）, huge amounts of genetic data constantly emerge. Research suggests that genes are not in independent existence and the expression of a gene will promote or inh...Along with the completion of HGP （human genome project）, huge amounts of genetic data constantly emerge. Research suggests that genes are not in independent existence and the expression of a gene will promote or inhibit the expression of another gene; if the expression of a gene makes the biochemical environment of ceils changed, the expression of a series of genes will be affected. In order to get a better understanding of the relationship between genes, all sorts of gene regulatory network models have been established by scientists. In this paper, a variety of gene regulatory networks are first introduced according to the process of this subject research, and then the most basic network （i.e. Boolean network） is emphatically analyzed, and then a new method （i.e. Boolean network based on the theory of circuit） to describe Boolean network is drawn forth. After the shortcomings of the Boolean network proposed in the past are analyzed, a simulation circuit Boolean model is established using EDA technology in order to improve the Boolean network.展开更多
Skeletal muscle fitness plays vital roles in human health and disease and is determined by developmental as well as physiological inputs. These inputs control and coordinate muscle fiber programs, including capacity f...Skeletal muscle fitness plays vital roles in human health and disease and is determined by developmental as well as physiological inputs. These inputs control and coordinate muscle fiber programs, including capacity for fuel burning, mitochondrial ATP production, and contraction. Recent studies have demonstrated crucial roles for nuclear receptors and their co-activators, and micro RNAs(mi RNAs) in the regulation of skeletal muscle energy metabolism and fiber type determination. In this review, we present recent progress in the study of nuclear receptor signaling and mi RNA networks in muscle fiber type switching. We also discuss the therapeutic potential of nuclear receptors and mi RNAs in disease states that are associated with loss of muscle fitness.展开更多
文摘An accurate 1.08GHz CMOS LC voltage-controlled oscillator is implemented in a 0.35μm standard 2P4M CMOS process.A new convenient method of calculating oscillator period is presented.With this period calculation technique,the frequency tuning curves agree well with the experiment.At a 3.3V supply,the LC-VCO measures a phase noise of -82.2dBc/Hz at a 10kHz frequency offset while dissipating 3.1mA current.The chip size is 0.86mm×0.82mm.
基金financially supported by National Natural Science Foundation of China(No.61475094)National 973 Program of China(No.2013CB329202)
文摘Simultaneous dimming controlling and data transmission are usually required in a white LED based indoor visible light communication system.However,the diming controlling of LED normally interferes the data transmission due to the modulation nonlinearity of LED.In order to solve this problem,a scheme by separating the LEDs for the functions of dimming control and data transmission respectively is proposed in this paper.In the scheme,the LEDs used for dimming control function are driven by a dc amplified circuit,and the LEDs for data transmission are driven by a digital modulation circuit respectively.In this way,the modulation distortion to the data signal caused by the modulation nonlinearity can be avoided even if the dimming is at high level dc driven current.The proof-of-concept experiment of a 2.5Mbit/s visible light communication system demonstrates that the dimming controlling and data transmission can be realized simultaneously in a simple way,and the data transmission is not affected by the dimming controlling function.Compared to previous methods,the scheme in this paper is simpler and cost effective,and makes sense when high rate data is transmitted in a visible light communication system.
文摘Along with the completion of HGP （human genome project）, huge amounts of genetic data constantly emerge. Research suggests that genes are not in independent existence and the expression of a gene will promote or inhibit the expression of another gene; if the expression of a gene makes the biochemical environment of ceils changed, the expression of a series of genes will be affected. In order to get a better understanding of the relationship between genes, all sorts of gene regulatory network models have been established by scientists. In this paper, a variety of gene regulatory networks are first introduced according to the process of this subject research, and then the most basic network （i.e. Boolean network） is emphatically analyzed, and then a new method （i.e. Boolean network based on the theory of circuit） to describe Boolean network is drawn forth. After the shortcomings of the Boolean network proposed in the past are analyzed, a simulation circuit Boolean model is established using EDA technology in order to improve the Boolean network.
基金supported by the Model Animal Research Center of Nanjing University Start Fundthe Jiangsu Natural Science Foundation(BK20140600)
文摘Skeletal muscle fitness plays vital roles in human health and disease and is determined by developmental as well as physiological inputs. These inputs control and coordinate muscle fiber programs, including capacity for fuel burning, mitochondrial ATP production, and contraction. Recent studies have demonstrated crucial roles for nuclear receptors and their co-activators, and micro RNAs(mi RNAs) in the regulation of skeletal muscle energy metabolism and fiber type determination. In this review, we present recent progress in the study of nuclear receptor signaling and mi RNA networks in muscle fiber type switching. We also discuss the therapeutic potential of nuclear receptors and mi RNAs in disease states that are associated with loss of muscle fitness.
