目的:研究电针治疗乳腺增生病疗效的发挥与肋间神经调节途径是否具有一定的关系。方法:选用SD大鼠随机分为A组(空白组)、B组(造模组)、C组(正常治疗组)、D组(肋间神经切断后治疗组)。B、C、D组均制备成乳腺增生模型动物,通过...目的:研究电针治疗乳腺增生病疗效的发挥与肋间神经调节途径是否具有一定的关系。方法:选用SD大鼠随机分为A组(空白组)、B组(造模组)、C组(正常治疗组)、D组(肋间神经切断后治疗组)。B、C、D组均制备成乳腺增生模型动物,通过手术将D组大鼠左侧第7肋间神经切断。随后,选用背组穴:天宗、肝俞、肾俞,均双侧;胸组穴:屋翳、合谷(均双侧)、膻中两组穴位交替使用,进行电针治疗,每日1次,5 d 1个疗程,疗程间休息2 d,共治疗20次。治疗结束后,采用乳房外观测定、电镜观察乳腺超微结构、免疫荧光法测定乳腺组织中ERα和PR两种受体含量变化。结果:正常治疗组和肋间神经切断治疗组乳房外观测定、电镜超微结构观察均有改善,乳腺组织中ERα蛋白下调(P〈0.05)、PR蛋白上调(P〈0.05);且正常电针组要优于肋间神经切断组(P〈0.05)。结论:电针治疗乳腺增生的疗效机制可能与肋间神经通路具有密切关系,且发挥疗效的机制可能是通过调节乳腺组织中ERα和PR蛋白含量实现的。展开更多
In the present paper, the therapeutic effect of hand acupuncture, moxibustion and electroacupuncture (EA) is observed in the treatment of 46 cases of peripheral facial paralysis (treatment group) and compared with tha...In the present paper, the therapeutic effect of hand acupuncture, moxibustion and electroacupuncture (EA) is observed in the treatment of 46 cases of peripheral facial paralysis (treatment group) and compared with that of Western medicines (prednisone, Vitamin B1 and B12, dibazol) in other 42 facial palsy patients. Acupoints used are Fenchi (GB 20), Yifeng (TE 17), Taiyang (LR 3), Yangbai (GB 14), Cuanzhu (BL 2), Yingxiang (LI 20), Dicang (ST 4), Shuigou (GV 26), Chengjiang (CV 24), Xiaguan (ST 7) and Jiache (ST 6). Following 20 - 30 sessions of treatment, results show that the therapeutic effect of treatment group is significantly superior to that of Western medicine group and the therapeutic duration of the former group is shorter.展开更多
In order to explore the effects of the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis,a controlled study was carded out among the treatment group (electro...In order to explore the effects of the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis,a controlled study was carded out among the treatment group (electro-acupuncture with strong stimulation),the control group Ⅰ(medication) and the control group Ⅱ (conventional acupuncture).The results showed that the differences in the cure rate and the total effective rate between the treatment group and the two control groups were significant in statistical analysis (P<0.05 and P<0.01 respectively).This indicates that better therapeutic effects can be obtained by the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis.展开更多
In the present paper, 176 cases of lumbar intervertebral disc protrusion are treated with electroacupuncture (EA) and topical heat irradiation. Local tender-point is used as the main acupoint, combined with Tunzhong, ...In the present paper, 176 cases of lumbar intervertebral disc protrusion are treated with electroacupuncture (EA) and topical heat irradiation. Local tender-point is used as the main acupoint, combined with Tunzhong, Tiaoyue, Weizhong (BL 40) and Yanglingquan (GB 34). The treatment is conducted once daily, with 15 sessions being a therapeutic course. Following treatment, of 176 cases, 46 (26. 1%) are cured, 90 (51. 1%) have prominent improvement, 35 (19.8%) have amelioration and 5 (2.8%) have no apparent changes, with a total effective rate of 97.0%.展开更多
Objective: To observe the therapeutic effect of clinical treatment of acute urticaria chiefly by electroacupuncture (EA). Methods: A total of 180 outpatients with acute urticaria were randomized into treatment group a...Objective: To observe the therapeutic effect of clinical treatment of acute urticaria chiefly by electroacupuncture (EA). Methods: A total of 180 outpatients with acute urticaria were randomized into treatment group and control group. 100 cases in the treatment group were treated with EA at Quchi (曲池 LI 11) and Xuehai (血海 SP 10) as the main points which were supplemented with Dazhui (大椎 GV 14), Fengchi (风池 GB 20), Geshu (膈俞 BL 17), Pishu (脾俞 BL 20), etc. 80 cases in the control group were managed by chlorpheniramine maleate and Vitamin C. Results: After 3 days’ treatment, of the 100 and 80 cases in treatment and control groups, 79 and 53 were cured, 10 and 6 markedly effective, 5 and 8 effective, and 6 and 13 failed, with the effective rates being 94.00% and 83.75% respectively. The therapeutic effect of electroacupunture was significantly superior to that of medication(P<0.05). Conclusion: The method of electroacupuncture at Quchi (曲池 LI 11), Xuehai (血海 SP 10),etc. was a more effective therapy for acute urticaria.展开更多
Thirty Wistar rats were randomly and evenly divided into control group, cerebral ischemia group and ischemia + electroacupuncture (EA) group. The bilateral common carotid arteries were occluded to induce acute cerebra...Thirty Wistar rats were randomly and evenly divided into control group, cerebral ischemia group and ischemia + electroacupuncture (EA) group. The bilateral common carotid arteries were occluded to induce acute cerebral ischemia. Nitric oxide (NO) and endothelin (ET)contents in the cerebral tissues and blood were measured under normal condition, immediately after ischemia and following EA. Results showed that after acute cerebral ischemia NO and ET contents in the cerebral tissues increased significantly (P<0.01) while serum ET increased and serum NO lowered obviously (P<0.05). Following EA of Baihui (GV 20) and Dazhui (GV 14), both NO and ET in cerebral tissues and serum turned to normal basically. It showed that EA could protect the cerebral tissues from injury induced by ischemia, NO and ET might participate in the modulation process of EA.展开更多
In the present study, the effect of electroacupuncture (EA) on immune system was observed in the rat by using micro- whole blood direct immunofluorescence staining assay to detect changes of the peripheral blood T lym...In the present study, the effect of electroacupuncture (EA) on immune system was observed in the rat by using micro- whole blood direct immunofluorescence staining assay to detect changes of the peripheral blood T lymphocyte subgroup and employing red blood cell (RBC) C 3b receptor- yeast rosette test and red blood cell-IC rosette test to analyze erythrocytic immune function. Results showed that after EA of “Zusanli" (ST 36), CD+ 4, RBC-C 3bRR and RBC-ICR in the peripheral blood of the normal rats increased significantly while CD+ 8 had no any considerable changes and a positive correlation between CD+ 4 and RBC-C 3bRR was found. In immunosuppression model rats, the values of CD+ 4 and RBC-C 3bRR were obviously lower than those of the normal control group while CD+ 8 had no any striking changes; but after EA treatment, there were no evident differences between EA group and normal control group in the above-mentioned indexes. There were also no any significant differences between non-acupoint group and normal control group in those indexes. Results suggest that EA of “Zusanli" (ST 36) can raise T cell immune function and RBC adhesion function in both normal rats and immunosuppression model rats, both of which present a positive correlation.展开更多
In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison wi...In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.展开更多
Point selection along the course of meridians is the basic principle for acupuncture prescription and selection of points. In application, there are three categories of point selection: selection of local and adjacent...Point selection along the course of meridians is the basic principle for acupuncture prescription and selection of points. In application, there are three categories of point selection: selection of local and adjacent points; selection of distant points, and selection of symptomatic points. Based on the展开更多
Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an ...Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an anxiety state in Web of Science,Cochrane Library,PubMed,Excerpta Medica Database(EMBASE),China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and Chongqing VIP Database(VIP)were retrieved by computer.The retrieval time was from each database’s inception to December 30,2022.Data extraction and evaluation were performed for the included studies.The Cochrane risk of bias assessment tool was used to assess the risk of bias in each article.Meta-analysis of valid data was performed using the RevMan 5.4 software.If the outcome indicator was a categorical variable,relative risk(RR)was used as the effect size.If it was a continuous variable,mean difference(MD)was used to calculate the effect size.Each effect size was expressed as a 95%confidence interval(CI).P<0.05 was considered to indicate a statistically significant difference.Results:A total of 18 studies were included,comprising a total of 1198 patients.The findings of the meta-analysis showed that electroacupuncture had a significant advantage in improving the Hamilton anxiety scale(HAMA)score than benzodiazepines[MD=-1.61,95%CI(-2.17,-1.06),P<0.001].Acupuncture was superior to sham acupuncture[MD=-14.90,95%CI(-20.39,-9.41),P<0.001]and benzodiazepines[MD=-3.39,95%CI(-4.67,-2.12),P<0.001]in reducing the self-rating anxiety scale(SAS)score.Acupuncture was superior to sham acupuncture in reducing the insomnia severity index(ISI)score[MD=-5.61,95%CI(-6.63,-4.89),P<0.001].Acupuncture was superior to benzodiazepines[MD=0.84,95%CI(-1.42,-0.25),P=0.005]and sham acupuncture[MD=-8.39,95%CI(-8.39,-7.86),P<0.001]in improving the Pittsburgh sleep quality index(PSQI)score.Acupuncture had a better effective rate than benzodiazepines[RR=1.16,95%CI(1.08,1.25),P<0.001]and sham acupuncture[RR=8.94,95%CI(4.63,17.25),P<0.001]in treating PI.Conclusion:Acupuncture or electroacupuncture has certain therapeutic advantages over benzodiazepines and sham acupuncture in the treatment of anxiety in PI patients.However,more high-quality randomized controlled trials are needed for further verification.展开更多
Objective To explore the effects of different acupuncture-moxibustion methods on the plasma substance P(SP) content,and the expression of colonic SP m RNA of the rats with functional constipation.Methods Sixty healt...Objective To explore the effects of different acupuncture-moxibustion methods on the plasma substance P(SP) content,and the expression of colonic SP m RNA of the rats with functional constipation.Methods Sixty healthy male SD rats were divided into six groups according to the random number table,including blank control group(group B,n=8),model group(group M,n=11),drug control group(group D,n=8),filiform needle group(group F,n=11),electroacupuncture group(group E,n=11) and moxibustion group(group MB,n=11).The rats in group B and group M accepted no intervention,gavage with cisapride suspension was conducted in group D,and electroacupuncture,filiform needling and moxibustion therapies were carried out in group E,group F and group MB for 6 days.After treatment,the stool quantity and fecal moisture content during 24 h of the rats were observed in each group,colon tissue structure and the acidic mucus in mucosa layer were observed,plasma SP content was detected and the expression of colonic SP m RNA was detected.Results compared with group B,the stool quantity and fecal moisture content during 24 h of the rats in group M decreased significantly(P0.01);compared with group M,the stool quantity during 24 h of the rats in each group increased(P0.05 or 0.01),and the fecal moisture content during 24 h of the rats in each group also increased significantly except group MB(P0.01);compared with group D,the fecal moisture content during 24 h of the rats in group MB decreased(P0.01);according to the comparison among the groups with different acupuncture-moxibustion methods,there was no difference in the stool quantity during 24 h of the rats in each group(P0.05),the fecal moisture contents during 24 h of the rats in group F and group E were higher than that of group MB(P0.01),and there was no difference between group F and group E(P0.05).HE staining of colon tissue of rats showed that the structure was normal and complete,and there was no difference among each group.PAS staining showed that the acidic mucus level of the rats in group M decreased significantly when compared with group B;compared with group M,the acidic mucus level of the rats in group D,fgroup F,group E and group MB increased in varying degrees.Compared with group B,the plasma SP content of the rats in group M decreased(P0.05);compared with group M,the plasma SP contents of the rats in group F and group MB increased(P0.01);the plasma SP contents of the rats in group F,group MB and group E were higher than that of group D(P0.05 or 0.01);according to the comparison among the groups with different acupuncture-moxibustion methods,the plasma SP content of the rats in group F was higher than that of group MB and electro-acupuncture group(P0.05),and there was no difference between group MB and group E.Compared with group B,the expression level of colonic SP m RNA of the rats in group M elevated(P0.05);compared with group M,the expression level of colonic SP m RNA of the rats in the four intervention groups declined(P0.05);compared with drug group D,there was no difference among group F,group E and group MB(P0.1);according to the comparison among the groups with different intervention methods,the expression level of colonic SP m RNA of the rats in group MB was lower than that of group F(P0.05).Conclusion The different efficacy of different acupuncture-moxibustion methods in treatment of functional constipation may be related with the mechanism of regulation of plasma SP content and the expression level of colonic SP m RNA.展开更多
Objective To compare the therapeutic effect on simple obesity of gastrointestinal heat type between electroacupuncture (EA) and conventional acupuncture (CA). Methods Ninety cases of simple obesity of gastrointest...Objective To compare the therapeutic effect on simple obesity of gastrointestinal heat type between electroacupuncture (EA) and conventional acupuncture (CA). Methods Ninety cases of simple obesity of gastrointestinal heat type were randomized into an EA group and a CA group, 45 cases in each one. In the EA group, CA was applied at Neiting (内庭 ST 44), Shangjuxu (上巨虚 ST 37), Xiajuxu (下巨虚 ST 39), Fenglong (丰隆 ST 40), Tianshu (天枢 ST 25), Zusanli (足三里 ST 36), YTnlingquan (阴陵泉 SP 9) and Ouchi (曲池 LI 12). The electric stimulation was attached at ST 37, ST 44, ST 25 and ST 40. In CA group, the simple acupuncture was applied at the same points as the EA group. The treatment was given once every two days, 22 treatments made one session and 3 sessions were required totally in the two groups. The changes in body mass, obesity degree, body mass index (BMI) and body fat percentage (F%) were observed in the patients before and after treatment. The therapeutic effects on weight loss and fat loss were compared between the two groups. Results After treatment, the weight, obesity degree, BMI and F% were all reduced apparently in the patients of the two groups (all P〈0.01). After the 2st session of treatment, concerning to the effect on weight loss, the total effective rate in the EA group was superior to that in the CA group [95.6% (43/45) vs 77.8% (35/45), P〈0.05]. The effects were not different apparently between the two groups in the later 2 sessions of treatment (all P〉0.05). The effect on fat loss was not different significantly in statistics between EA and CA (all P〉0.05). Conclusion Either EA or CA achieves the significant effect on simple obesity. The therapeutic effect of EA on weight loss in the early stage is obviously superior to that of CA.展开更多
Objective To explore the better treatment of post-stroke depression. Methods Sixty cases of post-stroke depression ranged from mild to middle degree were randomly divided into comprehensive therapy group and medicatio...Objective To explore the better treatment of post-stroke depression. Methods Sixty cases of post-stroke depression ranged from mild to middle degree were randomly divided into comprehensive therapy group and medication group, 30 cases in each group. In comprehensive therapy group, electroacupuncture at temple-three-needle was mainly applied and Fluoxetine Hydrochloride capsule was taken by oral administration; in medication group, Fluoxetine Hydrochloride capsule was applied by oral administration. Functional Independent Measure (FIM) Scale and WHOQOL-BREF evaluation results before and after treatment were compared after 4 weeks treatment. Results Comparing with the FIM scores before treatment, the differences in the two groups were significant (both P0.01), and the improvement in comprehensive therapy group (74.97±9.52) was superior to that in medication group (66.70±9.23) (P0.01). Signif icant differences were presented statistically in comparison of index scores of WHOQOL-BREF before and after treatment in two groups (P0.05, P0.01), and it in comprehensive therapy group was superior to that in medication group (P0.05, P0.01). Conclusion Activities of daily life and quality of life of post-stroke depression can be significantly improved by electroacupuncture at temple-three-needle and oral administration of Fluoxetine Hydrochloride capsule.展开更多
Objective To compare the difference in the therapeutic effects on diarrhea- type irritable bowel syndrome (D-IBS) between acupuncture based on soothing the liver and strengthening the spleen and western medicine. Me...Objective To compare the difference in the therapeutic effects on diarrhea- type irritable bowel syndrome (D-IBS) between acupuncture based on soothing the liver and strengthening the spleen and western medicine. Methods Seventy cases were randomized into an acupuncture group and a western medicine group, 35 cases in each one. In the acupuncture group, the conventional acupuncture was applied at Tianshu {天枢 ST 25), Zusanli (足三里 ST 36), Shangjuxu {上巨虚 ST 37), Sanyinjiao (三阴交 SP 6), Taichong (太冲 LR 3) and so on. Electric stimulation was supplemented at bilateral ST 25. The treatment was given once a day, 3-4 treatments in a week. In the western medicine group, pinaverium bromide (dicetel) was prescribed for oral administration, 50 mg each time, three times a day. Four weeks made one session in the two groups. Separately, before treatment and after 1 session treatment, the integral of clinical symptom and the score in the scale of the quality of life measure for irritable bowel syndrome (IBS-Q OL) were observed for the patients in the two groups. The efficacy and recurrence rate were assessed in the two groups. Results The symptom integral and IBS-QOL score in the two groups were improved significantly after treatment Call P〈0.01), and the improvements in the acupuncture group were superior to that in the western medicine group (P〈0.01). The effective rate was 94.3% {33/35) in the acupuncture group, which was superior to 77.1% (27/35) in the western medicine group (P〈0.01). In 3 months, the recurrence rate was 36.4% (12/33) in the acupuncture group, which was lower apparently than 72.0% (18/25) in the western medicine group (P〈O.01). Conclusion Acupuncture therapy based on soothing the liver and strengthening the spleen achieves the superior efficacy on D-IBS as compared with western medication, pinaverium bromide. This therapy improves apparently the quality of life of the patients and is lower in recurrence rate.展开更多
Objective To compare the efficacy of treating obese patients with abnormity of lipids and serum leptin by dilatational wave or continuous wave of electroacupuncture combined with thunder-fire moxibustion in order to p...Objective To compare the efficacy of treating obese patients with abnormity of lipids and serum leptin by dilatational wave or continuous wave of electroacupuncture combined with thunder-fire moxibustion in order to provide a clinical basis for selecting wave types of electroacupuncture for different patterns of obesity. Methods Sixty obese patients with abnormal lipids and serum leptin were randomly divided into a dilatational wave group and a continuous wave group via random number table, with 30 cases in each group. They were divided by TCM differentiation into three types: stomachintestine excessive heat, weakness of the spleen-stomach and spleen-kidney yang deficiency, treated by electroacupuncture on Tianshu (天枢 ST 25), Daheng (大横 SP 15), Zusanli (足三里ST 36), Shangjuxu (上巨虚 ST 37), Fanglong (丰隆 ST 40), Yinlingquan (阴陵泉 SP 9), Quchi (曲池 LI 11), Zhigou (支沟 TE 6) and Hegu (合谷 LI 4) along with thunder-fire moxibustion. The frequency of electro-acupuncture in the dilatational wave group and the continuous wave group was 2 Hz/100 Hz and 2 Hz, respectively. Patients in the two groups were treated once a day, six times a week. The treatment lasted for 4 weeks with 3-month follow-up. Body mass and body fat percentage before and after the treatment, as well as during the follow-up, were compared. The effectiveness rates in the two groups were compared, and the efficacy statistics of patients with different TCM patterns in the dilatational wave group were also analyzed. Lipid levels of the patients in two groups before and after the treatment were measured with an automatic biochemical analyzer, and serum leptin levels were detected with flow cytometry system. Results After the treatment, the patients' blood lipids, serum leptin levels, body mass and body fat percentage were effectively reduced in the two groups; three months' follow-up witnessed continuous decline of obesity indicators (P〈0.01 or P〈0.05), and patients in the dilatat-ional wave group improved more significantly than those in continuous wave group (P〈0.05 or P〈0.01). The efficacy in the dilatational wave group was superior to that in the continuous wave group (P〈0.01). The best efficacy could be found among patients with weakness of the spleen and the stomach in the dilatational wave group. Conclusion Efficacy of treating obese patients with abnormity of lipids and serum leptin by electro-acupuncture combined with thunder-fire moxibustion in the dilatational wave group was significantly better than that of the continuous wave group, and efficacy for obese patients with weakness of the spleen and the stomach was superior to that of those with stomach-intestine excessive heat and spleen-kidney yang deficiency.展开更多
Objective:To observe the clinical efficacy of deep electroacupuncture(EA)at Baliao points in treating stress urinary incontinence(SUI).Methods:A total of 60 female patients with SUI were divided into two groups accord...Objective:To observe the clinical efficacy of deep electroacupuncture(EA)at Baliao points in treating stress urinary incontinence(SUI).Methods:A total of 60 female patients with SUI were divided into two groups according to the order of consultation,with 30 cases in each group.The control group was treated with pelvic floor muscle training.The treatment group was treated with deep EA at Baliao points[Shangliao(BL 31),Ciliao(BL 32),Zhongliao(BL 33)and Xialiao(BL 34)].Results:The total effective rate was 93.3%in the treatment group,versus 33.3%in the control group,and the total effective rate of the treatment group was significantly higher than that of the control group(P<0.05).After treatment,the scores of international consultation on incontinence questionnaire-short form(ICIQ-SF)and the volume of urinary leakage in both groups were lower than those before treatment(all P<0.05),and the ICIQ-SF score and the volume of urinary leakage in the treatment group were lower than those in the control group(both P<0.05).Conclusion:Deep EA at Baliao points with long needles can improve the clinical symptoms in female patients with SUI,and it has a better curative effect than pelvic floor muscle training.展开更多
文摘目的:研究电针治疗乳腺增生病疗效的发挥与肋间神经调节途径是否具有一定的关系。方法:选用SD大鼠随机分为A组(空白组)、B组(造模组)、C组(正常治疗组)、D组(肋间神经切断后治疗组)。B、C、D组均制备成乳腺增生模型动物,通过手术将D组大鼠左侧第7肋间神经切断。随后,选用背组穴:天宗、肝俞、肾俞,均双侧;胸组穴:屋翳、合谷(均双侧)、膻中两组穴位交替使用,进行电针治疗,每日1次,5 d 1个疗程,疗程间休息2 d,共治疗20次。治疗结束后,采用乳房外观测定、电镜观察乳腺超微结构、免疫荧光法测定乳腺组织中ERα和PR两种受体含量变化。结果:正常治疗组和肋间神经切断治疗组乳房外观测定、电镜超微结构观察均有改善,乳腺组织中ERα蛋白下调(P〈0.05)、PR蛋白上调(P〈0.05);且正常电针组要优于肋间神经切断组(P〈0.05)。结论:电针治疗乳腺增生的疗效机制可能与肋间神经通路具有密切关系,且发挥疗效的机制可能是通过调节乳腺组织中ERα和PR蛋白含量实现的。
文摘In the present paper, the therapeutic effect of hand acupuncture, moxibustion and electroacupuncture (EA) is observed in the treatment of 46 cases of peripheral facial paralysis (treatment group) and compared with that of Western medicines (prednisone, Vitamin B1 and B12, dibazol) in other 42 facial palsy patients. Acupoints used are Fenchi (GB 20), Yifeng (TE 17), Taiyang (LR 3), Yangbai (GB 14), Cuanzhu (BL 2), Yingxiang (LI 20), Dicang (ST 4), Shuigou (GV 26), Chengjiang (CV 24), Xiaguan (ST 7) and Jiache (ST 6). Following 20 - 30 sessions of treatment, results show that the therapeutic effect of treatment group is significantly superior to that of Western medicine group and the therapeutic duration of the former group is shorter.
文摘In order to explore the effects of the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis,a controlled study was carded out among the treatment group (electro-acupuncture with strong stimulation),the control group Ⅰ(medication) and the control group Ⅱ (conventional acupuncture).The results showed that the differences in the cure rate and the total effective rate between the treatment group and the two control groups were significant in statistical analysis (P<0.05 and P<0.01 respectively).This indicates that better therapeutic effects can be obtained by the local strong stimulation generated by electro-acupuncture for treatment of the upper segment ureterolithiasis.
文摘In the present paper, 176 cases of lumbar intervertebral disc protrusion are treated with electroacupuncture (EA) and topical heat irradiation. Local tender-point is used as the main acupoint, combined with Tunzhong, Tiaoyue, Weizhong (BL 40) and Yanglingquan (GB 34). The treatment is conducted once daily, with 15 sessions being a therapeutic course. Following treatment, of 176 cases, 46 (26. 1%) are cured, 90 (51. 1%) have prominent improvement, 35 (19.8%) have amelioration and 5 (2.8%) have no apparent changes, with a total effective rate of 97.0%.
文摘Objective: To observe the therapeutic effect of clinical treatment of acute urticaria chiefly by electroacupuncture (EA). Methods: A total of 180 outpatients with acute urticaria were randomized into treatment group and control group. 100 cases in the treatment group were treated with EA at Quchi (曲池 LI 11) and Xuehai (血海 SP 10) as the main points which were supplemented with Dazhui (大椎 GV 14), Fengchi (风池 GB 20), Geshu (膈俞 BL 17), Pishu (脾俞 BL 20), etc. 80 cases in the control group were managed by chlorpheniramine maleate and Vitamin C. Results: After 3 days’ treatment, of the 100 and 80 cases in treatment and control groups, 79 and 53 were cured, 10 and 6 markedly effective, 5 and 8 effective, and 6 and 13 failed, with the effective rates being 94.00% and 83.75% respectively. The therapeutic effect of electroacupunture was significantly superior to that of medication(P<0.05). Conclusion: The method of electroacupuncture at Quchi (曲池 LI 11), Xuehai (血海 SP 10),etc. was a more effective therapy for acute urticaria.
文摘Thirty Wistar rats were randomly and evenly divided into control group, cerebral ischemia group and ischemia + electroacupuncture (EA) group. The bilateral common carotid arteries were occluded to induce acute cerebral ischemia. Nitric oxide (NO) and endothelin (ET)contents in the cerebral tissues and blood were measured under normal condition, immediately after ischemia and following EA. Results showed that after acute cerebral ischemia NO and ET contents in the cerebral tissues increased significantly (P<0.01) while serum ET increased and serum NO lowered obviously (P<0.05). Following EA of Baihui (GV 20) and Dazhui (GV 14), both NO and ET in cerebral tissues and serum turned to normal basically. It showed that EA could protect the cerebral tissues from injury induced by ischemia, NO and ET might participate in the modulation process of EA.
文摘In the present study, the effect of electroacupuncture (EA) on immune system was observed in the rat by using micro- whole blood direct immunofluorescence staining assay to detect changes of the peripheral blood T lymphocyte subgroup and employing red blood cell (RBC) C 3b receptor- yeast rosette test and red blood cell-IC rosette test to analyze erythrocytic immune function. Results showed that after EA of “Zusanli" (ST 36), CD+ 4, RBC-C 3bRR and RBC-ICR in the peripheral blood of the normal rats increased significantly while CD+ 8 had no any considerable changes and a positive correlation between CD+ 4 and RBC-C 3bRR was found. In immunosuppression model rats, the values of CD+ 4 and RBC-C 3bRR were obviously lower than those of the normal control group while CD+ 8 had no any striking changes; but after EA treatment, there were no evident differences between EA group and normal control group in the above-mentioned indexes. There were also no any significant differences between non-acupoint group and normal control group in those indexes. Results suggest that EA of “Zusanli" (ST 36) can raise T cell immune function and RBC adhesion function in both normal rats and immunosuppression model rats, both of which present a positive correlation.
文摘In the present study, the effect of electroacupuncture (EA) of acupoints of Ren, Spleen and Stomach Meridians on artificial abortion induced side effects was observed in 100 artificial abortion women. In comparison with 45 artificial abortion women in the control group (who had not accepted EA treatment), EA possessed significant effects in relieving abdominal pain, reducing vaginal bleeding duration, lowering infection rate and infertility rate after artificial abortion operation.
文摘Point selection along the course of meridians is the basic principle for acupuncture prescription and selection of points. In application, there are three categories of point selection: selection of local and adjacent points; selection of distant points, and selection of symptomatic points. Based on the
文摘Objective:To evaluate the clinical efficacy of acupuncture in the treatment of anxiety state in patients with primary insomnia(PI).Methods:Randomized controlled trials of acupuncture treatment for PI patients with an anxiety state in Web of Science,Cochrane Library,PubMed,Excerpta Medica Database(EMBASE),China National Knowledge Infrastructure(CNKI),Wanfang Data Knowledge Service Platform(Wanfang),and Chongqing VIP Database(VIP)were retrieved by computer.The retrieval time was from each database’s inception to December 30,2022.Data extraction and evaluation were performed for the included studies.The Cochrane risk of bias assessment tool was used to assess the risk of bias in each article.Meta-analysis of valid data was performed using the RevMan 5.4 software.If the outcome indicator was a categorical variable,relative risk(RR)was used as the effect size.If it was a continuous variable,mean difference(MD)was used to calculate the effect size.Each effect size was expressed as a 95%confidence interval(CI).P<0.05 was considered to indicate a statistically significant difference.Results:A total of 18 studies were included,comprising a total of 1198 patients.The findings of the meta-analysis showed that electroacupuncture had a significant advantage in improving the Hamilton anxiety scale(HAMA)score than benzodiazepines[MD=-1.61,95%CI(-2.17,-1.06),P<0.001].Acupuncture was superior to sham acupuncture[MD=-14.90,95%CI(-20.39,-9.41),P<0.001]and benzodiazepines[MD=-3.39,95%CI(-4.67,-2.12),P<0.001]in reducing the self-rating anxiety scale(SAS)score.Acupuncture was superior to sham acupuncture in reducing the insomnia severity index(ISI)score[MD=-5.61,95%CI(-6.63,-4.89),P<0.001].Acupuncture was superior to benzodiazepines[MD=0.84,95%CI(-1.42,-0.25),P=0.005]and sham acupuncture[MD=-8.39,95%CI(-8.39,-7.86),P<0.001]in improving the Pittsburgh sleep quality index(PSQI)score.Acupuncture had a better effective rate than benzodiazepines[RR=1.16,95%CI(1.08,1.25),P<0.001]and sham acupuncture[RR=8.94,95%CI(4.63,17.25),P<0.001]in treating PI.Conclusion:Acupuncture or electroacupuncture has certain therapeutic advantages over benzodiazepines and sham acupuncture in the treatment of anxiety in PI patients.However,more high-quality randomized controlled trials are needed for further verification.
基金Supported by Young Talents Program of Hebei Higher Education Institutions:BJ2014047Scientific Research Fund Project for Doctors of Hebei University of Chinese Medicine:BSZ2015009National Natural Science Foundation
文摘Objective To explore the effects of different acupuncture-moxibustion methods on the plasma substance P(SP) content,and the expression of colonic SP m RNA of the rats with functional constipation.Methods Sixty healthy male SD rats were divided into six groups according to the random number table,including blank control group(group B,n=8),model group(group M,n=11),drug control group(group D,n=8),filiform needle group(group F,n=11),electroacupuncture group(group E,n=11) and moxibustion group(group MB,n=11).The rats in group B and group M accepted no intervention,gavage with cisapride suspension was conducted in group D,and electroacupuncture,filiform needling and moxibustion therapies were carried out in group E,group F and group MB for 6 days.After treatment,the stool quantity and fecal moisture content during 24 h of the rats were observed in each group,colon tissue structure and the acidic mucus in mucosa layer were observed,plasma SP content was detected and the expression of colonic SP m RNA was detected.Results compared with group B,the stool quantity and fecal moisture content during 24 h of the rats in group M decreased significantly(P0.01);compared with group M,the stool quantity during 24 h of the rats in each group increased(P0.05 or 0.01),and the fecal moisture content during 24 h of the rats in each group also increased significantly except group MB(P0.01);compared with group D,the fecal moisture content during 24 h of the rats in group MB decreased(P0.01);according to the comparison among the groups with different acupuncture-moxibustion methods,there was no difference in the stool quantity during 24 h of the rats in each group(P0.05),the fecal moisture contents during 24 h of the rats in group F and group E were higher than that of group MB(P0.01),and there was no difference between group F and group E(P0.05).HE staining of colon tissue of rats showed that the structure was normal and complete,and there was no difference among each group.PAS staining showed that the acidic mucus level of the rats in group M decreased significantly when compared with group B;compared with group M,the acidic mucus level of the rats in group D,fgroup F,group E and group MB increased in varying degrees.Compared with group B,the plasma SP content of the rats in group M decreased(P0.05);compared with group M,the plasma SP contents of the rats in group F and group MB increased(P0.01);the plasma SP contents of the rats in group F,group MB and group E were higher than that of group D(P0.05 or 0.01);according to the comparison among the groups with different acupuncture-moxibustion methods,the plasma SP content of the rats in group F was higher than that of group MB and electro-acupuncture group(P0.05),and there was no difference between group MB and group E.Compared with group B,the expression level of colonic SP m RNA of the rats in group M elevated(P0.05);compared with group M,the expression level of colonic SP m RNA of the rats in the four intervention groups declined(P0.05);compared with drug group D,there was no difference among group F,group E and group MB(P0.1);according to the comparison among the groups with different intervention methods,the expression level of colonic SP m RNA of the rats in group MB was lower than that of group F(P0.05).Conclusion The different efficacy of different acupuncture-moxibustion methods in treatment of functional constipation may be related with the mechanism of regulation of plasma SP content and the expression level of colonic SP m RNA.
基金Naional Natural Science Fund Project: 30873307Jiangsu Characterisic Preponderant Discipline Fund ProjectFund Project of Outstanding Innovaion Team of Science and Technology in Jiangsu Colleges and Universiies Qinglan Engineering
文摘Objective To compare the therapeutic effect on simple obesity of gastrointestinal heat type between electroacupuncture (EA) and conventional acupuncture (CA). Methods Ninety cases of simple obesity of gastrointestinal heat type were randomized into an EA group and a CA group, 45 cases in each one. In the EA group, CA was applied at Neiting (内庭 ST 44), Shangjuxu (上巨虚 ST 37), Xiajuxu (下巨虚 ST 39), Fenglong (丰隆 ST 40), Tianshu (天枢 ST 25), Zusanli (足三里 ST 36), YTnlingquan (阴陵泉 SP 9) and Ouchi (曲池 LI 12). The electric stimulation was attached at ST 37, ST 44, ST 25 and ST 40. In CA group, the simple acupuncture was applied at the same points as the EA group. The treatment was given once every two days, 22 treatments made one session and 3 sessions were required totally in the two groups. The changes in body mass, obesity degree, body mass index (BMI) and body fat percentage (F%) were observed in the patients before and after treatment. The therapeutic effects on weight loss and fat loss were compared between the two groups. Results After treatment, the weight, obesity degree, BMI and F% were all reduced apparently in the patients of the two groups (all P〈0.01). After the 2st session of treatment, concerning to the effect on weight loss, the total effective rate in the EA group was superior to that in the CA group [95.6% (43/45) vs 77.8% (35/45), P〈0.05]. The effects were not different apparently between the two groups in the later 2 sessions of treatment (all P〉0.05). The effect on fat loss was not different significantly in statistics between EA and CA (all P〉0.05). Conclusion Either EA or CA achieves the significant effect on simple obesity. The therapeutic effect of EA on weight loss in the early stage is obviously superior to that of CA.
文摘Objective To explore the better treatment of post-stroke depression. Methods Sixty cases of post-stroke depression ranged from mild to middle degree were randomly divided into comprehensive therapy group and medication group, 30 cases in each group. In comprehensive therapy group, electroacupuncture at temple-three-needle was mainly applied and Fluoxetine Hydrochloride capsule was taken by oral administration; in medication group, Fluoxetine Hydrochloride capsule was applied by oral administration. Functional Independent Measure (FIM) Scale and WHOQOL-BREF evaluation results before and after treatment were compared after 4 weeks treatment. Results Comparing with the FIM scores before treatment, the differences in the two groups were significant (both P0.01), and the improvement in comprehensive therapy group (74.97±9.52) was superior to that in medication group (66.70±9.23) (P0.01). Signif icant differences were presented statistically in comparison of index scores of WHOQOL-BREF before and after treatment in two groups (P0.05, P0.01), and it in comprehensive therapy group was superior to that in medication group (P0.05, P0.01). Conclusion Activities of daily life and quality of life of post-stroke depression can be significantly improved by electroacupuncture at temple-three-needle and oral administration of Fluoxetine Hydrochloride capsule.
基金Supported by Leading Talent Project of Jiangsu Administraion of TCM: LJ 200905
文摘Objective To compare the difference in the therapeutic effects on diarrhea- type irritable bowel syndrome (D-IBS) between acupuncture based on soothing the liver and strengthening the spleen and western medicine. Methods Seventy cases were randomized into an acupuncture group and a western medicine group, 35 cases in each one. In the acupuncture group, the conventional acupuncture was applied at Tianshu {天枢 ST 25), Zusanli (足三里 ST 36), Shangjuxu {上巨虚 ST 37), Sanyinjiao (三阴交 SP 6), Taichong (太冲 LR 3) and so on. Electric stimulation was supplemented at bilateral ST 25. The treatment was given once a day, 3-4 treatments in a week. In the western medicine group, pinaverium bromide (dicetel) was prescribed for oral administration, 50 mg each time, three times a day. Four weeks made one session in the two groups. Separately, before treatment and after 1 session treatment, the integral of clinical symptom and the score in the scale of the quality of life measure for irritable bowel syndrome (IBS-Q OL) were observed for the patients in the two groups. The efficacy and recurrence rate were assessed in the two groups. Results The symptom integral and IBS-QOL score in the two groups were improved significantly after treatment Call P〈0.01), and the improvements in the acupuncture group were superior to that in the western medicine group (P〈0.01). The effective rate was 94.3% {33/35) in the acupuncture group, which was superior to 77.1% (27/35) in the western medicine group (P〈0.01). In 3 months, the recurrence rate was 36.4% (12/33) in the acupuncture group, which was lower apparently than 72.0% (18/25) in the western medicine group (P〈O.01). Conclusion Acupuncture therapy based on soothing the liver and strengthening the spleen achieves the superior efficacy on D-IBS as compared with western medication, pinaverium bromide. This therapy improves apparently the quality of life of the patients and is lower in recurrence rate.
基金Supported by Guangxi Natural Science Foundation Project:2010 GXNSFA 013210
文摘Objective To compare the efficacy of treating obese patients with abnormity of lipids and serum leptin by dilatational wave or continuous wave of electroacupuncture combined with thunder-fire moxibustion in order to provide a clinical basis for selecting wave types of electroacupuncture for different patterns of obesity. Methods Sixty obese patients with abnormal lipids and serum leptin were randomly divided into a dilatational wave group and a continuous wave group via random number table, with 30 cases in each group. They were divided by TCM differentiation into three types: stomachintestine excessive heat, weakness of the spleen-stomach and spleen-kidney yang deficiency, treated by electroacupuncture on Tianshu (天枢 ST 25), Daheng (大横 SP 15), Zusanli (足三里ST 36), Shangjuxu (上巨虚 ST 37), Fanglong (丰隆 ST 40), Yinlingquan (阴陵泉 SP 9), Quchi (曲池 LI 11), Zhigou (支沟 TE 6) and Hegu (合谷 LI 4) along with thunder-fire moxibustion. The frequency of electro-acupuncture in the dilatational wave group and the continuous wave group was 2 Hz/100 Hz and 2 Hz, respectively. Patients in the two groups were treated once a day, six times a week. The treatment lasted for 4 weeks with 3-month follow-up. Body mass and body fat percentage before and after the treatment, as well as during the follow-up, were compared. The effectiveness rates in the two groups were compared, and the efficacy statistics of patients with different TCM patterns in the dilatational wave group were also analyzed. Lipid levels of the patients in two groups before and after the treatment were measured with an automatic biochemical analyzer, and serum leptin levels were detected with flow cytometry system. Results After the treatment, the patients' blood lipids, serum leptin levels, body mass and body fat percentage were effectively reduced in the two groups; three months' follow-up witnessed continuous decline of obesity indicators (P〈0.01 or P〈0.05), and patients in the dilatat-ional wave group improved more significantly than those in continuous wave group (P〈0.05 or P〈0.01). The efficacy in the dilatational wave group was superior to that in the continuous wave group (P〈0.01). The best efficacy could be found among patients with weakness of the spleen and the stomach in the dilatational wave group. Conclusion Efficacy of treating obese patients with abnormity of lipids and serum leptin by electro-acupuncture combined with thunder-fire moxibustion in the dilatational wave group was significantly better than that of the continuous wave group, and efficacy for obese patients with weakness of the spleen and the stomach was superior to that of those with stomach-intestine excessive heat and spleen-kidney yang deficiency.
文摘Objective:To observe the clinical efficacy of deep electroacupuncture(EA)at Baliao points in treating stress urinary incontinence(SUI).Methods:A total of 60 female patients with SUI were divided into two groups according to the order of consultation,with 30 cases in each group.The control group was treated with pelvic floor muscle training.The treatment group was treated with deep EA at Baliao points[Shangliao(BL 31),Ciliao(BL 32),Zhongliao(BL 33)and Xialiao(BL 34)].Results:The total effective rate was 93.3%in the treatment group,versus 33.3%in the control group,and the total effective rate of the treatment group was significantly higher than that of the control group(P<0.05).After treatment,the scores of international consultation on incontinence questionnaire-short form(ICIQ-SF)and the volume of urinary leakage in both groups were lower than those before treatment(all P<0.05),and the ICIQ-SF score and the volume of urinary leakage in the treatment group were lower than those in the control group(both P<0.05).Conclusion:Deep EA at Baliao points with long needles can improve the clinical symptoms in female patients with SUI,and it has a better curative effect than pelvic floor muscle training.