期刊文献+
共找到3篇文章
< 1 >
每页显示 20 50 100
男性不同发育阶段靶组织中雄激素水平生理性变化 被引量:3
1
作者 崔毓桂 傅广波 +2 位作者 张桂元 钱立新 狄福松 《国际生殖健康/计划生育杂志》 CAS 2009年第1期62-65,共4页
目的:研究中国汉族男性不同发育阶段靶组织中雄激素[睾酮(T)、双氢睾酮(DHT)]生理变化趋势,探讨其在主导男性性发育和成熟中的作用。方法:78例不同年龄的男性,因包茎或包皮过长行包皮环切术。年龄从出生后9个月至34岁。新鲜的包皮组织... 目的:研究中国汉族男性不同发育阶段靶组织中雄激素[睾酮(T)、双氢睾酮(DHT)]生理变化趋势,探讨其在主导男性性发育和成熟中的作用。方法:78例不同年龄的男性,因包茎或包皮过长行包皮环切术。年龄从出生后9个月至34岁。新鲜的包皮组织制备匀浆,其上清用放射免疫方法测定睾酮、DHT水平,浓度单位转化为每毫升蛋白pmol/mg,进行多项式曲线配合分析其变化趋势。选择8例4~6岁儿童、8例14~16岁发育期男子、6例24~26岁成年男子,进行组间比较分析。结果:通过雄激素生理性变化趋势的曲线和不同年龄组的组间比较发现,新生儿时期有短暂的高水平的睾酮和DHT,尤其是DHT。儿童时期靶组织中的睾酮和DHT保持低水平[(0.368±0.229)nmol/(mg·L)和(0.589±0.375)nmol/(mg·L)],T/DHT比值为0.752±0.405。随着青春期发育开始,靶组织中睾酮和DHT水平升高,并在14~16岁之间达到峰值[(1.120±0.278)nmol/(mg·L)和(2.394±0.813)nmol/(mg·L)],T/DHT比值0.376±0.161。成年后,靶组织中睾酮和DHT水平分别维持在较高水平[(1.184±0.295)nmol/(mg·mL)和(2.250±0.666)nmol/(mg·L)],T/DHT比值为0.511±0.164。结论:研究结果描绘男性不同发育阶段靶组织中雄激素水平的生理性变化趋势,也印证了靶组织中雄激素在介导性发育和维持性成熟中的重要作用。 展开更多
关键词 青春期发育 男性性成熟 雄激素 睾酮 双氢睾酮
下载PDF
Effects of the Integrated TCM-WM Treatment of Nephrotic Syndrome on Growth and Sexual Development
2
作者 江淑爱 虞坚尔 刘煜 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2000年第1期21-25,共1页
  Fifty children with nephrotic syndrome were treated by using herbal drugs for nourishing yin to reduce pathogenic fire, strengthening qi and tonifying the kidney, and promoting blood circulation and removing blood...   Fifty children with nephrotic syndrome were treated by using herbal drugs for nourishing yin to reduce pathogenic fire, strengthening qi and tonifying the kidney, and promoting blood circulation and removing blood stasis in combination with glucocorticoid and immunodepressant. The body height, secondary sex characters, age of the first spermatorrhea for male and of menarche for female children, bone age measured with roentgenograms on the left wrist in 50 cases of the treatment group were compared with those in 31 cases of the control group treated by glucocorticoid and immunodepressant. The results showed that the delay of growth and sexual development as side-effects of glucocorticoid and immunodepressant were markedly reduced by the integrated TCM-WM treatment. 展开更多
关键词 Anti-Inflammatory Agents CHILD Child Development Child Preschool Combined Modality Therapy Drugs Chinese Herbal Female Humans Male Nephrotic Syndrome PREDNISONE Sexual Maturation
全文增补中
Early social conditions affect female fecundity in hermaphrodites 被引量:2
3
作者 Elio CANNARSA Mafia Cristina LORENZI Gabriella SELLA 《Current Zoology》 SCIE CAS CSCD 2015年第6期983-990,共8页
Social conditions experienced prior to sexual maturity influence reproduction later in life in many animals. In simulta- neous hermaphrodites, variation in mating group size influences reproductive investment. As the ... Social conditions experienced prior to sexual maturity influence reproduction later in life in many animals. In simulta- neous hermaphrodites, variation in mating group size influences reproductive investment. As the mating group size increases, re- productive resources devoted to the female function decrease in favor of the male function. Prior to sexual maturity, many her- maphrodites have a protandrous phase during which they produce sperm and can fertilize hermaphrodites' eggs. In the simulta- neously hermaphroditic polychaete worm Ophryotrocha diadema, the cost of male reproduction during adolescence is spread over the whole energy budget of worms as shown by a reduced growth rate, a delayed age at sexual maturity and the shortening of life span compared to protandrous males that do not reproduce. Little is known on whether social conditions experienced dur- ing development affect reproductive investment of immature individuals. We investigated whether social conditions affected the length of the protandrous phase, body size and also the subsequent female fecundity of same-age protandrous individuals of O. diadema, which did not had to face competition for egg fertilization. Results show that in large group sizes protandrous males lengthened their protandrous phase, slowed down body growth and decreased their individual investment at the first egg laying compared to protandrous males that were reared in isolation. In the successive egg layings worms adjusted their egg output to the current social conditions. We interpreted these results as an indication that early social conditions represent a social stress result- ing in a reduction of the overall reproductive resources up to the first egg laying . 展开更多
关键词 Social stress Early experience Ophryotrocha diadema Female fecundity Social environment
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部