黄河水源地“三致”物监测必要性与断面布设探讨

在河流污染物中，致癌物、致突变物、致畸形物（简称“三致”物）毒性最强，对人体健康威胁最大。据检测，在黄河干流兰州段、包头段和郑州段等河段已存在一定程度的“三致”物污染，应尽早开展饮用水水源地“三致”毒物污染监测。根据沿黄城市的分布情况及河段污染特点，可在兰州市包兰桥断面、包头市镫口断面、郑州市花园口断面及河口段利津断面首先开展监测工作。

权力步入市场的消极效应

'一个在野的首相不过是一个雄辩滔滔的演说家,而一个离开军队的将军不过是集镇上无精打采的英雄'。这种唯利是图的权力得失观,使历史上无数才华横溢者沦为野心家式的悲剧人物;在市场经济的大潮中,又使一些丧失理智的执掌一定权力的人坠入罪恶的深渊。因此,权力进入市场是反腐倡廉、加强干部队伍建设中尤其值得注意与警觉的现象。权力经济:社会发展的畸形物市场经济的基本法则是在社会机会均等条件下的公平竞争。

High density porous polyethylene material (Medpor) as an unwrapped orbital implant

Objective: To introduce the clinical effect among patients who received an unwrapped orbital implant with high density porous polyethylene material (Medpor) after enucleation or evisceration. Methods: Retrospective analysis of a series of 302 patients with anophthalmia who underwent placement of an unwrapped high density porous polyethylene orbital implant. We compared the patients (n=180) who accepted primary implant placement with those (n=122) who accepted secondary implant placement. Parameters evaluated included: age at time of surgery, date of surgery, sex, implant type and size, surgery type, the surgical procedure and technique performed, and complications. Results: The time of follow-up ranged from 2.0 to 58.0 months (mean 32.5 months). A total of 5 of 302 (1.66%) cases had documented postoperative complications. The following problems were noted after surgery: implant exposure, 3 patients (0.99%); implant removed due to orbital infection, 1 patient (0.34%); ptosis, 1 patient (0.34%). There were no significant complications observed in other 297 cases and all implants showed good orbital mo- tility. The clinical effect of primary implant placement is better than that of secondary placement. Conclusion: High density porous polyethylene material can be used successfully as an unwrapped orbital implant in anopthalmic socket surgery with minimal complications. The material is well tolerated, nonantigenic and has low rate of infection and migration.

Deformities in silver pomfret Pampus argenteus caught from Kuwait waters

During sampling for spawning stock of the silver pomfret,Pampus argenteus in Kuwait waters,a few seriously deformed individuals were captured.These individuals had been attacked and wounded,but had healed and survived.The fish body deformities are believed to be caused by predation attempts on silver pomfret by predators such as sharks,groupers,and croakers.

Biomechanical principle of arcus plantaris and its clinical application

To analyze the principle mechanism of the arcus plantaris and its clinical application. Methods: The states of forces sustained by the arcus plantaris were analyzed and calculated according to the mechanism of the quadratic parabolic arch. Results: The aponeurosis plantaris corresponded to the pull rod of the arcus plantaris. The medial and lateral longitudinal arches formed by the pedal bones were stable with the rod, but unstable without the rod. In the latter condition, on loading, the force sustained by the parabolic arch became a force sustained by a simple beam, and the arcus plantaris tended to disappear and to be flattened. Clinically, 240 feet with talipes equinus were treated with triple arthrodesis. In 34 out of the reexamined 156 feet, the aponeurosis plantaris was cut in addition to the triple arthrodesis and was immobilized with cast for 3 months. One or two years later, their arcus plantaris disappeared, pain developed when walking, and some of them walked with the midtarsal joint against the ground. Then, the triple arthrodesis and shortening of the aponeurosis plantaris were applied on 18 cases, and osteotomy of the calcaneus and reconstruction of the aponeurosis plantaris were made on 10 cases and satisfactory effects were obtained. Conclusions: In order to achieve satisfactory therapeutic effects of the triple arthrodesis, we should reestablish the arcus plantaris and accurately treat the aponeurosis plantaris for the balance of the surrounding muscle force.

Loss of stat3 function leads to spine malformation and immune disorder in zebrafish

STAT （Signal Transducers and Activators of Transcription） gene family members have been revealed to be involved in cell growth and differentiation in vertebrates. Despite their physiological importance, their functions are poorly studied at organ and systemic levels. In this study, we performed a genome-wide analysis using data from invertebrates to vertebrates to identify STAT genes and analyze their evolutionary history. Interestingly, the STAT gene family undergoes genome duplications during the evolutionary history with STAT3 homologues firstly appearing in the basal extant vertebrate, sea lamprey, suggesting its possible roles in spine formation. To investigate the functions of stat3 in fish species, TALEN technology was performed to generate mutant zebrafish lines, star3 mutant zebrafish showed no obvious defects at early developmental stage but displayed severe lateral and vertical curvature of the spine （scoliosis）, spine fracture and the incomplete bone joints with narrower junction between vertebrae at early juvenile stage, as indicated by Alizarin red and Alcian blue staining, radiography and micro-computed tomography （MicroCT） analysis. Transcriptome analysis reveals dramatic alterations in a number of genes involved in immune and infection response, skeletal development and somatic growth, especially downregulated expression of collagen gene family, in the juvenile stat3 mutant zebrafish. Moreover, most of the collagen genes were detected to have abnormal expression pattern during the formation of spine deformities in stat3 mutants. Our data reveal that stat3 is specially expressed in vertebrates and required for normal spine development and immune function in zebrafish.