鼻穴“腰三角”穴籽压法治疗急性腰扭伤156例

鼻穴“腰三角”穴籽压法治疗急性腰扭伤１５６例张文华（江苏省沐阳县中医院，２２３６００）腰三角穴位于人体鼻部中央，共三穴，其上穴在鼻正中线，其余两穴分布在两侧鼻翼。根据中医全息论观点，鼻部作为人体之缩影，而“腰三角穴”之在鼻部的位置，又正似是在人体的腰...

Clinical observation of 125 I labeled anti alpha fetoprotein antibody radioimmunotherapy in hepatocellular carcinoma *

AIM To observe the therapeutic effects and toxic side reactions of 125 I labeled hourse anti human AFP polyclonal antibodies in immuno targeting therapy against hepatocellular carcinoma (HCC).

Thirty Cases of Acute Lumbar Sprain Treated by Acupuncture Combined with Point-Injection at Tianzhu

In recent years, the authors have treated 30 cases of acute lumbar sprain by acupuncture combined with point medicinal injection at Tianzhu (BL 10), and obtained quite good therapeutic results, as is reported in the following.

Treatment of Hyperlipemia by Acupoint Catgut-embedding in 34 Cases

With the therapeutic method of acupoint catgut embedding, the authors have in recent years treated hyperlipemia and achieved satisfactory therapeutic results. A report follows.

CLINICAL STUDY ON TREATMENT OF INFANTILE PRIMARY EPILEPSY WITH ACUPOINT CATGUT-IMPLANTATION THERAPY

Aim: To observe the therapeutic effect of acupoint catgut implantation therapy in the treatment of infantile primary epilepsy. Methods: A total of 63 cases of primary epilepsy children were randomly divided into medication group (n=32) and acupoint catgut implantation group (n=31) and treated respectively with Sodium Valproate 5-10 mg/kg/d and catgut implantation at Changqiang (GV 1), Jiuwei (CV 15), bilateral Xinshu (BL 15) and bilateral Zusanli (ST 36). Results: Following 60 days of treatment, the abnormal changes of electroencephlogram (EEG), the seizure frequency and duration and clinical symptoms were improved apparently in comparison with those of pre treatment, but no significant differences were found between the two groups (P>0.05). There was a significant difference between two groups in the cure rate of the short term effect (P<0.05), with the therapeutic effect of the treatment group being superior to that of medication group. Conclusion: Acupoint catgut implantation therapy has a good therapeutic effect in the treatment of primary infantile epilepsy.

CLINICAL OBSERVATION ABOUT THE EFFECT OF BLOOD-LETTING OF JING-POINTS ON CEREBRAL BLOOD FLOW IN STROKE PATIENTS AT THE EARLY STAGE AND EXPERIMENTAL STUDY ON ITS MECHANISMS IN THE RABBIT

In this paper, the authors sum their research results about the effect of blood-letting of Jing (Well)-point on cerebral blood flow both in stroke patients and in experimental cerebral ischemia, cerebral hematoma and hypertension rabbits. In 30 cases of stroke (cerebral hemorrhage and cerebral infarction) patients, blood flow state of the anterior cerebral artery (ACA), middle cerebral artery (MCA) and the posterior cerebral artery (PCA), and the blood flow velocity of the bilateral vertebral artery (VA) and the basil artery (BA) are determined before and after pricking blood of the Twelve Jing-points. In experimental cerebral ischemia (by occlusion of the common carotid artery) rabbits, cerebral hematoma model rabbits and intravenous injection of noradrenaline induced hypertension rabbits, rheoencephalogram (REC) is detected before and after blood letting of the twelve "Jing"-points. In these 30 stroke patients, ultrasound Doppler examination’s results show that in 22 cases (73.33%) whose blood flow velocity decreases, after blood-letting of the 12 Jing-points, it increases significantly (P<0.01); in the rest 8 cases ( 26.67%) whose blood flow velocity speeds up, after treatment, it decreases evidently (P<0.01), showing a good dual-directional regulative effect of blood-letting therapy. In experimental cerebral ischemia rabbits, cerebral hematoma rabbits and hypertension rabbits whose REG lowers in the amplitude apparently (P<0.01), after blood letting stimulation of the 12 Jing-points, it increases at different degrees. Three patterns of stimulation as blood letting stimulation, pain stimulation and Jing-point stimulation, also the 3 factors of blood-letting therapy, may contribute to their effect on improvement of the cerebral blood flow. Somatic afferent nerve, sympathetic nerve of the vascular wall, central cholinergic nerve (M receptors) and adrenergic nerve (α receptors) participate in the effect of blood letting on cerebral blood flow.

Treatment of Migraine with Acupuncture at Points Pertaining to the Liver and Gallbladder Channels

In studying the syndrome of yang-hyperactivity, we found that most migraine patients were with hyperactivity of the liver-yang, stagnation of the liver-qiand blood stasis, and stagnation of the liverqi and deficiency of the spleen. To evaluate the needling effects on migraine and to approach its mechanism, we have launched a study in 207 cases since 1997. The results were satisfactory and reported as follows.

SEGMENTAL DISTRIBUTION OF AFFERENT ELECTRO-ACUPUNCTURE SIGNALS FROM ACUPOINTS OF THE PERICARDIUM MERIDIAN IN THE RAT

Objective: To observe the segmental distribution of afferent Electroacupuncture (EA) signals from acupoints of the Pericardium (PC) Meridian and try to analyze the relative specificity of running route of PC Meridian.Methods: A total of 85 Wistar rats anesthetized with mixed solution of Chloralose (5 mg/100 g) and Urethane (42 mg/100g) were used in this study. Under microscopic observation, the micro-filaments of the distal end of the dorsal root were carefully separated after tearing the spinal pia mater to attach to a recording electrode. The reference electrode was placed beneath the skin of the incision. Two caudal and two rostral dorsal roots near the recorded one were cut off separately. Electrical activity of the isolated micro-filaments was observed before and after EA of "Daling" (PC 7) -"Jianshi" (PC 5), "Quze" (PC 3) of PC Meridian, "Yangchi"(TE 4)- "Zhigou" (TE 6), "Tianjing" (TE 10)-" Qin-glengyuan" (TE 11) of the Triple Energizer (TE) Meridian with electric current 1 mA and 2 mA and double pulses. Results: ① After EA (1 mA) of "Daling"(PC 7)-"Jianshi"(PC 5), the firing rates of 3 out of 10 (33.3%) micro-filaments in C5 segment, 5 out of 10 (50.0%) in C6, 7 out of 10 (70.0%) in 07, 3 out of 10 (30.0%) in C8 and 3 out of 13 (23. 1%) in T1 increased considerably；and after EA of "Quze" (PC 3), those of 3/10 of C5, 4/10 of C6, 6/10 of C7, 3/10 of C8, and 3/10 of T1 increased significantly. ② After EA (1 mA) of "Yangchi"(TE 4)- "Zhigou" (TE 6) and "Tianjing" (TE 10)- "Qinglengyuan" (TE 11). the firing rates of 2/10, 2/10 of micro-filaments In C5, 7/10, 3/10 of C6, 5/10 and 4/10 of C7, 1/10 and 1/10 of C8, and 2/13 and 1/10 of T1 increased significantly. It indicates that C7 dorsal root may play the first important role in conveying EA signals from PC Meridian acupoints to the spinal cord, while C6 and C7 may be mainly responsible for conveying EA signals from TE Meridian acupoints to the spinal cord. Conclusion: The peripheral afferent pathway for transmitting EA signals from PC Meridian acupoints probably has a relative specificity.

Point Injection for Treating Nephritic Colic in 101 Cases

Since 1994, the authors have treated 101 cases of nephritic colic by point injection therapy and achieved good curative results.

CLINICAL OBSERVATION ON 67 CASES OF VASCULAR HEADACHE TREATED BY NEEDLING FOR BLOODLETTING PLUS POINT EMBEDDING

Objective: To observe the therapeutic effect of bloodletting plus point implantation of catgut in the treatment of 67 cases of vascular headache. Methods: A total of 107 cases of vascular headache patients were divided into treatment group (n=67) and control group (n=40). Bilateral Taiyang (EX-HN 5) and Jiaosun (TE 20) were pricked with a needle to let a little blood out, once every 4 days. Bilateral Fengmen (BL 12) and Ganshu (BL 18) were used for embedding catgut, once every 16 days. Patients of control group were ordered to take Rotunding, Oryzanol and Nimodipine, 3 times daily. Results: After 16 days’ treatment, of the 67 cases in treatment group, 26 were cured, 37 responded with improvement in their symptoms and 4 failed; while of the 40 cases in control group, 10 were cured, 19 responded with improvement in their symptoms and 11 failed. The total effective rate of treatment group was significantly superior to that of control group (P<0.01). In addition, the time of headache disappearance of treatment group was strikingly shorter than that of control group; while the duration of sleep of treatment group was strikingly longer than that of control group (P<0.01). Conclusion: The therapeutic effect of acupoint bloodletting plus acupoint embedding of catgut is superior to that of Western medicine in the treatment of vascular headache.

OBSERVATION ON THE THERAPEUTIC EFFECT OF ACUPOINT INJECTION FOR TREATMENT OF GOUTY ARTHRITIS

In the present paper, 60 cases of gouty arthritis patients were randomly divided into acupuncture group (n=30) and acupoint injection group (n=30). In these two groups, the tender point was used as the main acupoint, combined with Taichong (LR 3), Yinbai (SP 1), Sanyinjiao (SP 6), Juegu (GB 39), Xuehai (SP 10), etc. 10% Chishao (Radix Paeoniae Rubra) Injection and dexamethasone were used for acupoint injection. Results indicated that in acupoint injection and acupuncture groups, 15 (50.0%) and 9 (30.0%) cases had marked improvement, 12 (40.0%) and 10 (33.3%) were effective, and 3 (10.0%) and 11(36.7%) failed in treatment, with the total effective rats being 90.0% and 63.3% respectively. Statistical analysis shows that acupoint injection is significantly superior to simple acupuncture in the therapeutic effect (P<0.05).

Clinical Observation in 46 Cases of Angina Pectoris Treated by the Catgut-embedding Therapy

With the catgut-embedding therapy, the author treated 46 cases of angina pectoris from October 1997 to February 2002, and achieved good therapeutic results. This is reported as follows.

CLINICAL OBSERVATION ON 60 CASES OF BENIGN HYPERPLASIA OF PROSTATE TREATED BY INJECTION OF "CHUAN-SHEN-TONG" INJECTIOINTO HUIYIN (CV1)

Objective: To observe the therapeutic e ffect of injection of "Chuan-Shen-Tong" Injectio (川参通注射液) at Huiyin (会阴 CV 1) on benign hyperplasia of prostate . Methods: 60 cases of benign hyperplasia of prostate patients were evenly randomized into treatment group and control group. Those of treatment group were treated with injection o f "Chuan-Shen-Tong" Injectio (composed of Rhizoma Ligustici Chuanxiong, Rad ix Salviae Miltiorrhizae, etc. for relieving hyperplasis of prostate, 4 mL/acupoin t) into Huiyin (CV 1) and the other 60 cases of control group were treated by oral administration of Hytrin (1 mg/d in the 1 st week and increasing 1 mg/3 d, 4 mg at m ost). After 28 days’ treatment, their therapeutic effects were compared. Result s: After treatment, of each 60 cases in treatment and control groups, 11 (18.3%) and 11 (11.7%) were controlled in their symptoms, 25 (41.7%) and 16 (26.7%) had marked improvement, 18 (30.0%) and 17 (28.3%) had improvement, and 6 (10.0%) an d 20 (33.3%) failed, with the effective rate and the markedly effective rate bei ng 90.0% and 66.7% in the treatment group and 66.7% and 38.3% in the control gro up respectively. The therapeutic effect of treatment group was significantly sup erior to that of control group (P<0.01 and P< 0.05). Conclusion: The therapeutic effect of point-injection of "Chuan-Shen-Tong" for benign hyperplasia of p rostate is better than that of oral administration of Hytrin.

OBSERVATION ON THERAPEUTIC EFFECT OF LOCAL SELECTION OF POINTS COMBINED WITH ABDOMINAL ACUPUNCTURE FOR FACIAL SPASM

Objective To observe the therapeutic effect of local selection of points combined with abdominal acupuncture in the treatment of facial spasm. Methods Eighty cases of facial spasm were randomly divided into treatment group and control group, 40 cases in each group,treated respectively by abdominal acupuncture combined with local selected points and local points simply. After 30 sessions of treatment, the therapeutic effect was evaluated. Results In the treatment group, the total effective rate reached 92.5%, the curative rate 75.0%; while in the control group, the total effective rate was 80.0%, the curative rate 55.0% with a significant difference between the two groups ( P<0.05 ). Conclusion The therapeutic effect of abdominal acupuncture combined with local points is superior to that of simple local selection of points in the treatment of facial spasm.

Female Climacteric Syndrome Treated by Ear Embedding

Female climacteric syndrome is a common disease occurring before and after menopause. The author has treated the disease with ear embedding therapy, and achieved satisfactory therapeutic results. The following is a report of the clinical observation.

Auricular acupressure as assistant in primary insomnia management: a randomized single-blind controlled clinical trial

Objective: To observe the efficacy and safety of dexzopiclone plus auricular acupressure in intervening primary insomnia. Methods: A total of 72 participants who met the in clusi on criteria were en rolled in a ran domized con trolled trial, with 36 cases allocated to a treatment group and 36 cases allocated to a control group. Both groups were given dexzopiclone as the routine treatment. Patients in the treatment group were given auricular acupressure with Wang Bu Liu Xing (Semen Vaccariae) seeds at the auricular acupoints related to sleep and emotion based on meridian theory, whereas for patients in the control group, the medical plasters with Wang Bu Liu Xing (Semen Vaccariae) seeds were only gently stuck to acupoints unrelated to sleep without stimulation. Patients in both groups were required to visit the hospital once a week for replacing the seeds and plasters. The course of intervention lasted for 8 weeks and the patients were followed up for another 4 weeks. Pittsburgh sleep quality index (PSQI) and Karolinska sleep diary (KSD) were used to evaluate the outcomes. Meanwhile, adverse effects were monitored and recorded. Results: In the enrolled 72 cases, 4 patients (one in the treatment group and three in the control group) reported thirst and a bitter taste, and one case in the control group reported nausea and vomiting. At last, 3 cases in the control group dropped out for adverse reactions, and 69 cases completed the clinical trial. After 8 weeks of treatment, the global scores of PSQI in both treatment and control groups decreased significantly compared with the baseline (both PvO.001). Furthermore, the global score of PSQI in the treatment group was lower than that in the control group (P<0.01). The global scores of PSQI in both groups at the follow-up were significantly different from the baseline (both PvO.001), but insignificantly different compared with the post-treatment results (both P>0.05). According to KSD, both treatment protocols could prolong the total sleep time, shorten sleep-onset latency, improve sleep efficacy and sleep quality significantly, and the changes in the treatment group were more significant. The total effective rate was 88.9% in the treatment group, higher than 81.8% in the control group, though the difference was statistically insignificant (P>0.05). Con elusion: Dexzopicl one plus auricular acupressure is effective and safe for pati ents with primary in somnia both in short and long terms, and it is more effective tha n mono therapy of dexzopicl one.

Clinical study on acupoint massage in improving cognitive function and sleep quality of elderly patients with hypertension

Objective：To investigate the effects of acupoint massage on cognitive function and sleep quality in elderly patients with hypertension. Methods：A total of 68 elderly patients with hypertension were enrolled, and their ages were all over 60 years old. They were divided into a control group and a treatment group by simple random method, with 34 cases in each group. Patients in the control group were treated by routine psychological health guidance and sleep knowledge education, while patients in the treatment group were treated by acupoint massage on the base of the interventions given to the control group. Both of their treatment courses were 3 months. Pittsburgh sleep quality index （PSQI） scores and mini-mental state examination （MMSE） scores before and after treatment were recorded and compared. Results：Two groups’ PSQI scores before treatment had no significant difference （P〉0.05）. After 3 months of treatment, their PSQI scores were statistically different （P〈0.05）. There was also no between-group statistical difference in MMSE score before treatment （P〉0.05）, but there was a significant difference after treatment （P〈0.05）. Conclusion：Acupoint massage for elderly patients with primary hypertension can improve their sleep quality and enhance their cognitive function, thus it is worthy of being applied in clinical nursing work.

Observation on clinical effects of acupuncture plus external medicine application for cervical radiculopathy

Objective： To observe the clinical effects of acupuncture plus external medicine application for cervical radiculopathy. Methods： A total of 98 patients with cervical radiculopathy were randomly divided into an observation group and a control group based on the random digital table. The observation group （50 cases） was treated by acupuncture plus external medicine application and the control group （48 cases） was treated by acupuncture alone. The patients received the treatment every day. Ten sessions made a course. Cervical spondylosis symptom scale was used to assess the cases before and after the treatment. The clinical efficacy was compared between the two groups after the treatment. Results： The total effective rate was 98.1% in the observation group versus 87.6% in the control group with a statistically significant difference between the two groups （P〈0.05）. The cure rate was 52.0% in the observation group versus 18.8% in the control group with a significant difference between the two groups （P〈0.05）. There was no significant difference in the score of cervical spondylosis symptom scale between the two groups before the treatment （P〉0.05）. It increased with a significant difference in both groups after the treatment （both P〈0.05）, while a significant difference was found in the results between the two groups after the treatment （P〈0.05）. Conclusion： Acupuncture plus external medicine application is more effective than acupuncture alone for treating cervical radiculopathy. The method also effectively improves the clinical symptoms.

Effects of acupoint thread-embedding therapy on serum apelin and GLP-1 in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen

Objective:To observe the effects of acupoint thread-embedding therapy on serum apelin and glucagon-like peptide-1(GLP-1)in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.Methods:Sixty-six patients were randomly divided into a control group and an observation group according to the random number table method,with 33 cases in each group.Patients in the control group were treated with exenatide and metformin,while patients in the observation group were treated with additional acupoint thread-embedding.After 12-week treatment,the obesity-related indicators,including body mass index(BMI),waist circumference and body fat rate,the glycometabolism indicators,including fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin,and the lipid metabolism indicators,including total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C),as well as serum apelin and GLP-1 levels were observed in patients of the two groups.Results:After treatment,the BMI,waist circumference and body fat rate of patients in the two groups were all reduced(all P<0.05),and were lower in the observation group than in the control group(all P<0.05);the fasting blood glucose,2 h postprandial blood glucose and glycosylated hemoglobin levels of patients in both groups were all decreased(all P<0.05),and were significantly lower in the observation group than in the control group(all P<0.05);the TC level was decreased(P<0.05),while the TG and LDL-C levels did not change significantly in the control group(both P>0.05);the TC,TG and LDL-C levels were all significantly reduced in the observation group(all P<0.05),lower than those in the control group(all P<0.05);the serum apelin level was decreased(P<0.05)and the serum GLP-1 level was increased(P<0.05)in the observation group,statistically different from those in the control group(both P<0.05).Conclusion:Combined with the conventional medication,acupoint thread-embedding therapy can significantly improve the obesity-related indicators,glycometabolism and lipid metabolism in type 2 diabetes mellitus patients with obesity due to dampness-heat encumbering spleen.This may be achieved by regulating the serum apelin and GLP-1 levels.

Observation on therapeutic effect of half puncture plus transcutaneous acupoint electric stimulation for infantile facial paralysis

Objective：To observe the clinical effects of half puncture plus transcutaneous acupoint electric stimulation in the treatment of infantile facial paralysis. Methods：A total of 60 patients with infantile facial paralysis were divided into a treatment group and a control group by the random digital table, 30 cases in each group. The treatment group was treated with half puncture plus transcutaneous acupoint electric stimulation. The control group was treated with routine acupuncture. Before and after treatment, House-Brackmann （H-B） grading was used to evaluate the sick children respectively. The total effective rates were compared between the two groups after treatment. Results：After 6-course treatments, the total effective rate was 96.5% in the treatment group and 80.0% in the control group, there was a statistical difference between the two groups （P〈0.05） in comparison of the total effective rate. After 6-course treatments, H-B scores were all elevated than those before treatment in the two groups （P〈0.05）; there was a statistical difference between the two groups （P〈0.05）. Conclusion：Half puncture plus transcutaneous acupoint electric stimulation is better than routine acupuncture in curative effect for infantile facial paralysis.