Case HistoryMs.Li,a 58-year-old retired cadre,paid herfirst visit on Dec.7,1998,with the chief complaintsof headache,fever,nasal obstruction,cough,andgeneral pain with anhidrosis for two days.Whenplaying with her gran...Case HistoryMs.Li,a 58-year-old retired cadre,paid herfirst visit on Dec.7,1998,with the chief complaintsof headache,fever,nasal obstruction,cough,andgeneral pain with anhidrosis for two days.Whenplaying with her grandson in the yard in the展开更多
Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind s...Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind since it has the functions of clearing heat and brightening the eye, dispelling wind and inducing resuscitation.展开更多
To study the antiviral effect of Hypericum perforatum L. extract （HPE） on influenza A virus （IAV） （H1N1） in vitro and in vivo. Cytopathic effect （CPE） and neutral red （NR） dye uptake were used to examine the...To study the antiviral effect of Hypericum perforatum L. extract （HPE） on influenza A virus （IAV） （H1N1） in vitro and in vivo. Cytopathic effect （CPE） and neutral red （NR） dye uptake were used to examine the antiviral effect of HPE on Madin Darby Canine Kidney （MDCK） cells which were infected with IAV in vitro HPE was effective against influenza A virus （IAV） in vitro, with a 50% effective concentration （EC50） of 40 ug/mL, The mean 50% cytotoxic concentration （CC50） in the MDCK used in these experiments was 1.5 mg/mL. Ribavirin was run in parallel with EC50 values of 5.0 ug/mL; the mean CC50 for ribavirin was 520 ug/mL. Oral gavage administrations of HPE or ribavirin to mice infected with the IAV were highly effective in preventing death, slowing the decline of arterial oxygen saturation, inhibiting lung consolidation and reducing lung virus titers. The minimum effective dose of HPE in these studies was 31.25 mg/kg/day, which was administered twice daily for 5 d beginning 4 h prior to virus exposure. Below a dosage of 2000 mg/kg/day, almost all treated mice survived, which suggests that HPE is of low toxicity. Ribavirin＇s minimum effective dose was 40 mg/kg/day with the LDso determined to be 200 mg/kg/day. Delay of the initiation of either HPE or ribavirin therapy, using approximately 1/3 LD50 dose each time, could still be protective as late as 48 h after exposure to the IAV. While both agents appeared to have similar efficacy against IAV infections, HPE was considered to be less toxic and may warrant further evaluation as a possible therapy for influenza.展开更多
Objective： To observe the real-time effect of scraping therapy for headache due to common cold. Methods： Forty-five patients with headache caused by cold were included to receive scraping therapy, and asked to take ...Objective： To observe the real-time effect of scraping therapy for headache due to common cold. Methods： Forty-five patients with headache caused by cold were included to receive scraping therapy, and asked to take hot water and a good rest after treatment. Visual Analog Scale （VAS） score was recorded before and after the scraping treatment. The patients were visited again at the second day to inspect the development of the disease, including whether the headache was relapsed or aggravated; how long it was between the relapse or aggravation and the scraping treatment; patients＇ behavior after the scraping treatment. Result： The VAS score ofpre-treatment was 6.45±1.95, and it was 1.43±0.65 after treatment. The results had statistical significance. In the revisit among the 45 patients, there were 39 patients whose headache didn＇t relapsed or aggravated. For the left 6 patients who got relapsed or aggravated headache, researcher found that they did not follow the doctor＇s order well. Conclusion： Scraping therapy has obvious real-time effect on headache caused by cold. However, whether the patients can follow the doctor＇s advice is a key factor in the relapse of headache.展开更多
文摘Case HistoryMs.Li,a 58-year-old retired cadre,paid herfirst visit on Dec.7,1998,with the chief complaintsof headache,fever,nasal obstruction,cough,andgeneral pain with anhidrosis for two days.Whenplaying with her grandson in the yard in the
文摘Fengchi (GB 20) is a point of the Gallbladder Channel of Foot-Shaoyang. Just as its name implies that it is a place where the pathogenic wind converges. So, the point is regarded as an important point to dispel wind since it has the functions of clearing heat and brightening the eye, dispelling wind and inducing resuscitation.
基金One Hundred Person Project of The Chinese Academy of Sciences (2008-287) The Project of Basic Scientific Research Fund for Central Public-Welfare of Institute of Sciences (BRF070402).
文摘To study the antiviral effect of Hypericum perforatum L. extract （HPE） on influenza A virus （IAV） （H1N1） in vitro and in vivo. Cytopathic effect （CPE） and neutral red （NR） dye uptake were used to examine the antiviral effect of HPE on Madin Darby Canine Kidney （MDCK） cells which were infected with IAV in vitro HPE was effective against influenza A virus （IAV） in vitro, with a 50% effective concentration （EC50） of 40 ug/mL, The mean 50% cytotoxic concentration （CC50） in the MDCK used in these experiments was 1.5 mg/mL. Ribavirin was run in parallel with EC50 values of 5.0 ug/mL; the mean CC50 for ribavirin was 520 ug/mL. Oral gavage administrations of HPE or ribavirin to mice infected with the IAV were highly effective in preventing death, slowing the decline of arterial oxygen saturation, inhibiting lung consolidation and reducing lung virus titers. The minimum effective dose of HPE in these studies was 31.25 mg/kg/day, which was administered twice daily for 5 d beginning 4 h prior to virus exposure. Below a dosage of 2000 mg/kg/day, almost all treated mice survived, which suggests that HPE is of low toxicity. Ribavirin＇s minimum effective dose was 40 mg/kg/day with the LDso determined to be 200 mg/kg/day. Delay of the initiation of either HPE or ribavirin therapy, using approximately 1/3 LD50 dose each time, could still be protective as late as 48 h after exposure to the IAV. While both agents appeared to have similar efficacy against IAV infections, HPE was considered to be less toxic and may warrant further evaluation as a possible therapy for influenza.
文摘Objective： To observe the real-time effect of scraping therapy for headache due to common cold. Methods： Forty-five patients with headache caused by cold were included to receive scraping therapy, and asked to take hot water and a good rest after treatment. Visual Analog Scale （VAS） score was recorded before and after the scraping treatment. The patients were visited again at the second day to inspect the development of the disease, including whether the headache was relapsed or aggravated; how long it was between the relapse or aggravation and the scraping treatment; patients＇ behavior after the scraping treatment. Result： The VAS score ofpre-treatment was 6.45±1.95, and it was 1.43±0.65 after treatment. The results had statistical significance. In the revisit among the 45 patients, there were 39 patients whose headache didn＇t relapsed or aggravated. For the left 6 patients who got relapsed or aggravated headache, researcher found that they did not follow the doctor＇s order well. Conclusion： Scraping therapy has obvious real-time effect on headache caused by cold. However, whether the patients can follow the doctor＇s advice is a key factor in the relapse of headache.
