普瑞巴林与卡马西平分别联合甲钴胺分散片治疗带状疱疹后神经痛的疗效分析

目的观察普瑞巴林与卡马西平分别联合甲钴胺分散片治疗带状疱疹后神经痛的疗效及不良反应的对比分析。方法将60例带状疱疹后神经痛的患者分为普瑞巴林组(30例)和卡马西平组(30例):采用视觉模拟量表(VAS)评估本治疗患者用药前和用药后1周、2周、4周时疼痛情况及观察其伴随症状。结果普瑞巴林组治疗带状疱疹后神经痛优于卡马西平组(P<0.05)。结论普瑞巴林较卡马西平更能快速、强效的缓解并缩短带状疱疹后神经痛的持续时间,延长睡眠时间,降低不良反应发生率。

带状疱疹及疹后神经痛治疗体会

带状疱疹及疹后神经痛治疗,结果随诊6个月治愈。

Observation on the effect of fire needle combined with Linggui Bafa for post-herpetic neuralgia

Objective To observe the clinical effect of fire needle combined with Linggui Bafa for post-herpetic neuralgia （PHN）. Methods One hundred and twenty patients were randomly divided into an observation group and a control group with 60 cases each. For observation group, fire needle was applied to prick Zusanli （足三里 ST 36）, Yanglingquan （阳陵泉 GB 34）, Taichong （太冲 LR 3）, Sanyinjiao （三阴交 SP 6） and partial Ashi points around the lesion, and Linggui Bafa was combined to perform acupuncture therapy, once every other day, 10 times as a course of treatment; for the control group, only fire needle was applied. After 2 courses of treatment, the comparison of the value of visual analogue scale （VAS） and the total effective rate for the two groups were carried out. Results The VAS value of the observation group after treatment was obviously lower than that before treatment （2.28±2.08 vs 6.12±1.96） and that of the control group （2.28±2.08 vs 3.62±2.90）, there were significant differences （all P〈0.01）. The total effective rate of the observation group was obviously higher than that of the control group [93.3% （56/60） vs 76.7% （46/60）], the difference between the two groups was statistically significant （P〈0.05）. Conclusion The effect of fire needle combined with Linggui Ba.fa for PHN is obviously superior to that of single fire needle therapy.

Needle-embedding therapy for fifty cases of post-herpetic neuralgia

Objective To observe the clinical efficacy of needle-embedding therapy for the treatment of post-herpetic neuralgia. Method Fifty patients of post-herpetic neuralgia treated with needle-embedding therapy from January 2013 to June 2014 at Department of pain of the Second People＇s Hospital of Yibin City were selected. At each time of needle-embedding therapy, 4-8 points were selected. Patients were treated once a day, 5 times for a course of treatment and received a total of 1-3 courses of treatment. Meanwhile, the curative effect was analyzed in accordance with Criteria of Diagnosis and Therapeutic Effect of Diseases and Syndromes in Traditional Chinese Medicine. Result Among the 50 patients, the markedly effective rate was 84.0% （42/50）, the effective rate was 16.0% （8/50） and the total effective rate was 100.0%. Conclusion Needle-embedding therapy for the treatment of post-herpetic neuralgia offers a good curative effect.

Clinical research on postherpetic neuralgia treated by floating-acupuncture combined with collateral-bloodletting puncture and cupping

Objective To observe the clinical efficacy of treating postherpetic neuralgia （PHN） by combining floating-acupuncture laser with cupping following collateral bloodletting, and to analyze its mechanism. Method One hundred and thirty cases of PHN were randomly divided into a floating-acupuncture laser with cupping following collateral bloodletting group （group A） and an electroacupuncture group （group B） based on the treatment sequence and according to the random number table, with 65 cases in each group. In the group B, G-6805 electroacupuncture apparatus was adopted after the arrival of qi through even reinforcing and reducing （even method） in such acupoints as Hegu （合俗 LI 4）, Taihong （太冲 LR 3）, Zhigou （支沟 TE 6）, Quchi （ 曲池 LI 11） and Zusanli （足三里 ST 36）; in the group A, the treatment combining floatingacupuncture laser with cupping following collateral bloodletting was adopted, and the score of VAS and clinical efficacy before and after treatment in the two groups were compared. Result The differences of VAS scores of the two groups between the time points of after one course of treatment, after the entire treatment, follow up visit three months after the treatment and before treatment were statistically significant （all P〈0.05）. The rate of significant efficiency and total effective rate in the group A were respectively 37.8% and 98.5% （64/65）, and 11.2% and 78.5% （52/65） in the group B. The difference between the two groups was statistically significant after Ridit analysis （P〈0.05）. Conclusion The efficacy of treating PHN by combining floating-acupuncture laser with cupping following collateral bloodletting was significant.

Thin cotton moxibustion combined with plum-blossom needle in treatment of herpes zoster:a controlled trial

Objective To compare the difference of clinical efficacy of thin cotton moxibustion combined with plum-blossom needle and western medication in treatment of herpes zoster.Method Eighty patients with herpes zoster were divided into thin cotton moxibustion group（group A,n=40） and western medication group（group B,n=40） according to the sequence of admission.Patients in group A received thin cotton moxibustion that the colton was used as thin as a cicada＇s wings,combined with plum-blossom needle,and patients in group B received intravenous infusion with 0.25 g of acyclovir once a day,and acyclovir ointment application on affected part for 3-5 times per day.Five days were considered as a course of treatment.Analgesic effect and the incidence of postherpetic neuralgia were observed after two consecutive courses.Result The total effective rate was 97.5%（39/40） in group A,and80.0%（32/40） in group B（P〈0.05）;it was shown from the comparison of course between two groups that the cure rate after one in group A was markedly higher than that in group B（P〈0.01,P〈0.05）;the differences in effectual time and analgesic time between group A and group B were statistically significant（P〈0.05）;after treatment,the incidence of postherpetic neuralgia in group A was markedly lower than that in group B（P〈0.05）.Conclusion Thin cotton moxibustion combined with plum-blossom needle in treatment of herpes zoster can obviously shorten the time of therapy,effectively control pain,and reduce the incidence of postherpetic neuralgia.

Observation on therapeutic effect of combined therapy mainly based on acupuncture for postherpetic neuralgia

Objective To compare the difference in therapeutic effect between the combined therapy mainly based on acupuncture and western medicine in treating postherpetic neuralgia. Methods Eighty patients were randomly divided into a treatment group and a control group by ballot, and 40 patients were included in each group. The patients in the treatment group were treated by using the combined therapy mainly based on acupuncture, in other words, electroacupuncture at Jiáj （夹脊 EX-B2） and acupoint injection, and He-Ne laser therapy was also carried out. The patients in the control group were orally administered with 10 mg oxycodone controlled release tablets, twice a day; 0.5 mg mecobalamin tablets, three times a day. Scores for pain, sleep disorders and anxiety degree of the patients were recorded respectively, and the therapeutic effect in the two groups was counted. Results The total effective rate in the treatment group was 100.0% （40/40）, which was higher than 87.5% （35/40） in the control group; the markedly effective rate in the treatment group was 85.0% （34/40）, which was better than 65.0% （26/40） in the control group （both P0.05）. The therapeutic effects in reliefing pain, sleep disorders and anxiety of the patients in the treatment group were better than that in the control group （all P0.01）. Conclusion The combined therapy mainly based on acupuncture can effectively treat postherpetic neuralgia and the therapeutic effect is better than that in the western medicine group

Clinical Observation of Acupuncture Therapy for Postherpetic Neuralgia

Objective： To observe the clinical efficacy of acupuncture therapy for postherpetic neuralgia in the elders. Methods： Twenty-four cases of postherpetic neuralgia were randomized into two groups, an acupuncture group in which 12 cases were treated by acupuncture at Jiaji （Ex-B 2） on the diseased side, and a medication group in which 12 cases were treated by oral obtundent and intramuscular injection of neurotrophic drugs. Results： After four-week treatments, the total effective rate was 91.6% in the acupuncture group and 83.3% in the medication group. Conclusion： Acupuncture can significantly relieve postherpetic neuralgia, with better effects than medication.

Is fire needle superior to Western medication for herpes zoster?A systematic review and meta-analysis

Objective:To compare the effectiveness of fire needle versus Western medicine in the treatment of herpes zoster.Methods:Randomized controlled trials comparing fire needle with Western medicine in the treatment of herpes zoster were identified using 8 databases.A meta-analysis was performed using RevMan 5.3 software.Results:Eight trials involving 569 patients were included in this meta-analysis,and the results showed that fire needle was superior to Western medicine comparing the effective rate[risk ratio(RR)=1.13,95%confidence interval(Cl):1.06 to 1.20;P=0.0002],the visual analog scale(VAS)score[mean difference(MD)=-7.95;95%Cl:-10.71 to-5.20;P<0.00001],time of pain disappearance(MD=-7.61;95%CI:-9.38 to-5.84;P<0.00001),time of blister-stop(MD=-1.34,95%CI:-1.51 to-1.18;P<0.00001),time of crusted scab(MD=-2.92,95%CI:-3.62 to-2.23;P<0.00001);and time of scab off(MD=-4.64,95%CI:-5.83 to-3.46;P<0.00001).In addition,a significantly lower incidence of postherpetic neuralgia was found in the fire needle group in 30 d(RR=0.23,95%CI:0.11 to 0.51;P=0.0002)and 60 d(RR=0.33,95%CI:0.12 to 0.91;P=0.03)after treatment.Conclusion:Fire needle has a favorable effect in increasing the effective rate,relieving pain,recovering skin lesions and decreasing incidence of postherpetic neuralgia in the treatment of herpes zoster.However,considering the limitations in this study,the findings should be interpreted cautiously.

Micro-invasive Thread-embedding Therapy in Treating Postherpetic Neuralgia

Herpes zoster is a kind of acute herpes viral dermatosis induced by infection of varicella zoster virus, and is characterized by a painful skin rash with blisters. It often occurs in the areas innervated by intercostal, cervical, trigeminal, and lumbosacral nerves. As a feature of this disease, neuralgia happens before or together with the rash, radiating along the innervated areas. Elderly patients commonly suffer from a long-time residual neuralgia

Acupuncture combined with medication for postherpetic neuralgia affecting the head and face:a randomized controlled trial

Objective:To observe the efficacy of needling the Xi-Cleft points of yang meridians plus topical surrounding needling and pregabalin in treating postherpetic neuralgia(PHN)affecting the head and face and its influence on quality of life(QOL).Methods:Eighty patients with PHN affecting the head and face were randomized into an acupuncture-medication group and a Western medication group by their visiting sequence,with 40 cases in each group.The Western medication group took pregabalin capsules orally,75 mg each time,twice a day.The dosage could increase to 150 mg each time and twice a day within 1 week based on the efficacy and tolerance.The treatment lasted for 5 weeks.The acupuncture-medication group was given additional surrounding needling at the herpes zoster on the head and face,and Xi-Cleft points of yang meridians were chosen according to the affected area for acupuncture,once every other day,for 5 weeks in total.Results:Prior to treatment,there were no significant differences in the visual analog scale(VAS)and QOL scores between the two groups(both P>O,05).After treatment,VAS and QOL scores dropped significantly in both groups(all P<0.01),and were significantly lower in the acupuncture-medication group than in the Western medication group(both P<0.01).The total effective rate was 67.5%in the Western medication group,versus 92.5%in the acupuncture-medication group,and the b etwee n-group difference was statistically significant(P<0.05).Conclusion:Based on oral administration of pregabalin,needling the Xi-Cleft points of yang meridians and topical surrounding needling can reduce PHN,notably improve patients'QOL,and produce more significant efficacy than oral administration of pregabalin alone。