Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple cova...Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple covariates,and gives the sufficient conditions for uniform non-confoundingover a covariate set C including confounders or non-confounders,and also shows the conditions forconditionally non-confounding in the subpopulations.All these conditions can be tested by observeddata.展开更多
文摘目的研究川崎病(Kawasaki disease,KD)患儿急性期血脂水平与冠脉病变关系,探讨是否可以将血脂水平作为川崎病监测指标。方法回顾性分析2020年1月—2022年7月福建医科大学附属三明第一医院儿科收治的47例KD患儿资料,根据心脏彩超检查冠脉情况结果分为冠脉病变组(n=23)和冠脉正常组(n=24),同时进行血脂4项检测:三酰甘油(triglyceride,TG)、总胆固醇(total cholesterol,TC)、低密度脂蛋白胆固醇(low density lipoprotein cholesterol,LDL-C)、高密度脂蛋白胆固醇(high density lipoprotein cholesterol,HDL-C)。比较两组患儿TG、TC、LDL-C、HDL-C有无差异。结果KD患儿急性期(1~9 d病程)冠脉病变组测定的血TG、TC、LDL-C及HDL-C与冠脉正常组比较,差异有统计学意义(P<0.05)。结论KD患儿急性期血脂水平可作为早期诊断KD患儿并发冠脉病变的重要指标之一,具有理想的应用价值。
基金supported by the Natural Science Foundation China under Grant Nos. 10801019 and 10726037
文摘Causation is a distinct concept from association and more important than association inepidemiologic studies.This paper proposes the concept of uniform non-confounding for causal distributioneffects over multiple covariates,and gives the sufficient conditions for uniform non-confoundingover a covariate set C including confounders or non-confounders,and also shows the conditions forconditionally non-confounding in the subpopulations.All these conditions can be tested by observeddata.
