Objective: For the purpose of understanding the changingprocess of syphilis histomorphology and its injury mechanism,the ultrastructure of dermatic tissues of secondary syphiliswas studied. Methods: Different skin inj...Objective: For the purpose of understanding the changingprocess of syphilis histomorphology and its injury mechanism,the ultrastructure of dermatic tissues of secondary syphiliswas studied. Methods: Different skin injury tissues of secondary syphilispatients, whose serum RPR and TPHA tests in the lab bothappeared positive reaction, were observed throughtransmission electron microscope(TEM). Results: Inflammations appeared on epidermides and coria,a great deal of neutrocytes, lymphocytes and a small amountof plasma innltrated them. Karyopyknosis, karyorrhexis,epicyte lysis and mitochondrion vacular degenerationoccurred. Spirocheta pallida was distributed on intercellularsubstances, epicytes and collagenous fibers. The epicytes werepressed to foveation. Conclusion The pathological change ofcharacteristic tissue ultrastructure reported here is ahistomorphological foundation to study the organism injurymechanism caused by syphilis.展开更多
文摘Objective: For the purpose of understanding the changingprocess of syphilis histomorphology and its injury mechanism,the ultrastructure of dermatic tissues of secondary syphiliswas studied. Methods: Different skin injury tissues of secondary syphilispatients, whose serum RPR and TPHA tests in the lab bothappeared positive reaction, were observed throughtransmission electron microscope(TEM). Results: Inflammations appeared on epidermides and coria,a great deal of neutrocytes, lymphocytes and a small amountof plasma innltrated them. Karyopyknosis, karyorrhexis,epicyte lysis and mitochondrion vacular degenerationoccurred. Spirocheta pallida was distributed on intercellularsubstances, epicytes and collagenous fibers. The epicytes werepressed to foveation. Conclusion The pathological change ofcharacteristic tissue ultrastructure reported here is ahistomorphological foundation to study the organism injurymechanism caused by syphilis.
