应用淋巴细胞分层液提高血液病理细胞阳性检出率的研究

目的探讨应用淋巴细胞分层液提高血液病理细胞阳性检出率的研究价值。方法选取诊断为骨髓增生异常综合征(MDS)33例、恶性肿瘤17例、红斑狼疮8例、疟原虫病7例为研究对象,其分离细胞涂片作为研究组,相同患者外周血(无分离有核细胞)染片作为对照组。对比两种涂片阳性检出率。结果分离有核细胞研究组对MDS、肿瘤细胞、狼疮细胞及疟原虫的阳性检出率均高于与相同患者外周血对照组阳性检出率,差异均有统计学意义(P<0.05)。结论应用淋巴细胞分层液富集阳性细胞效果明显,对MDS、病理肿瘤细胞、寄生虫细胞、狼疮细胞的检出率有明显提高。

乳腺导管内肿物完形抓取活检对比单导管腺叶切除术临床分析

目的探讨完形抓取活检系统对乳管内单发肿物的治疗效果。方法回顾性分析2020年6月至2021年6月于西安交通大学第一附属医院乳腺外科行病灶完形抓取活检术和单导管腺叶切除术的单发导管内乳头状瘤各15例。分析两组患者的病理检出率,以及伤口长度、换药次数、住院时间、伤口愈合时间的临床恢复指标。结果病灶完形抓取活检术组的病理检出率为100.0%,高于单导管腺叶切除术组的86.7%,但差异无统计学意义(P>0.05)。病灶完形抓取活检术组患者的伤口长度为(0.85±0.23)cm,小于单导管腺叶切除术的(2.97±0.77)cm;病灶完形抓取活检术组的换药次数为(1.40±0.51)次、住院时间为(1.20±0.41)天、伤口愈合时间为(5.47±0.64)天,均短于单导管腺叶切除术组的(3.20±0.56)次、(2.87±0.64)天、(8.80±1.21)天,差异均有统计学意义(t值分别为10.225、9.222、8.469、9.449,P<0.01)。结论乳腺病灶完形抓取技术可一次性完整切除乳腺导管内肿物,提高了病理检出率,促进患者临床恢复,从而为诊断提供了更可靠的依据,为治疗提供了更安全的措施。

比较超声和CT在小儿急慢性阑尾炎诊断中的应用

探析超声和CT在小儿急慢性阑尾炎诊断中的效果。方法 对象:2023.1-2023.12月的102例疑似小儿急慢性阑尾炎患儿,分别落实超声以及CT检查,以手术病理结果为金标准,明确不同诊断方式的诊断效能;病理类型检出率。结果 在诊断效能方面,CT检查更具优势,P<0.05,在病理类型检出率方面,两种诊断方式无明显差异,P>0.05。结论 CT诊断在诊断效能方面更具优势,但是超声检查具有操作便捷的优势,在实际落实诊断工作的过程中,可结合实际需求选取最佳诊断方式。

芪术养胃汤联合西药治疗脾胃虚弱型慢性萎缩性胃炎的临床观察

慢性萎缩性胃炎（chronic atrophic gastritis,CAG）是临床常见的消化系统疾病,据统计CAG发病率位居胃病之首,电子胃镜、胃黏膜病理检出率高达7.5%~13.8%,且发病趋势趋于年轻化。

Changes in the clinicopathological characteristics of gastric cancer in Hehuang Valley of China–2379 cases of gastric cancer in recent 10 years

Objective： The aim of our studywas to discuss changes in the clinicopathological characteristics of gastric cancer in Hehuang Valley of China in recent 10 years. Methods： A retrospective case-control study was performed on 2379 newly-diagnosed gastric cancer patients. All of them came from Hehuang Valley. The patients were divided into two groups [recent 5 years （R5Y） and late 5 years （L5Y）] from February 2003 to February 2013, and the clinicopathological data were surveyed retrospectively. Results： The constituent ratio of upper 1/3 gastric cancer in R5Y and L5Y was 33.5% and 20.7%, respectively, and it showed a significant difference between the two groups （X2 = 21.28, P = 0.00）, The constituent ratio of squamous carcinoma/adenosquamous carcinoma was 2.7% and 1.6%, respectively, and it also showed a significant differ- ence between two groups （X2 = 50.91, P = 0.00）. The constituent ratio of moderately-poorly differentiated/poorly differentiated gastric carcinoma was 84.2% and 50.2%, respectively, and it showed statistically significant difference （X2 = 30.28, P = 0.00）. The detection rate of early gastric cancer （EGC） was 1.47% （35/2379）. The constituent ratio of the types of Borrmann II and Borrmann IV of advanced gastric cancer （AGC） among 2379 cases was 47.6% and 40.8%, respectively, and that still showed statistically significant difference （X2 = 18,80, P = 0.00）. The constituent ratio of diffuse-type of gastric cancer in R5Y and L5Y was 36.2% and 30.8%, respectively, even there was a significant difference （X2 = 7.49, P = 0.01）. Furthermore, there were also significant differences in regional lymph nodes metastasis, perineural infiltration and vascular invasion （P 〈 0.05）. The positive detection rate of HER2, ER and PR was 14.88%, 17.23% and 15.93%, respectively. The constituent ratio of HP in two groups was 43.8% and 36.2% respectively, and it also showed a significant difference （~2 = 13.51, P = 0.00）. Conclusion： The pathogenic sites in gastric cancer change to the upper stomach in Hehuang Valley in recent 10 years, and the detection rate of squamous carcinoma/adenosquamous carcinoma reveals a sharp rise. Borrmann III is still one of the main types of advanced gastric cancer, but the detection rates of Borrmann II and IV are increasing. The main type of gastric cancer is the intestinal- type, but the ratio of diffuse-type is also increasing in recent 10 years. The HP detection rate is 40.65% （967/2379）, and it has a slight rise in recent 10 years. The detection rate of poorly differentiated adenocarcinoma is increasing despite the fact that the moderately/moderately-poorly differentiated adenocarcinoma is the main histologic types. High detection rates of lymph nodes metastasis, perineural infiltration and vascular invasion indicate poor prognosis in patients with gastric cancer. There is no change in HER2 positive rate, on the contrary, there are a little increase in ER and PR expression in Hehuang Valley.

教职工180例心电图分析

本文对180例教职工体检心电图按一般心电图诊断方法进行分析,发现年龄在36岁以上的中老年教职工异常心电图(具有病理意义)检出率显著高于35岁以下的青年教职工,心电图病因分析,其严重程度也远远超过青年教职工。从而提出加强中老年知识分子心血管疾病的防治工作乃当前学校卫生工作之重要内容之一,应该引起重视。