Zinc （Zn） deficiencies are currently thought to cause chronic metabolic derangement leading to or exacerbating immune deficiencY, gastrointestinal problems, endocrine disorders, neurologic dysfunction, cancer, accel...Zinc （Zn） deficiencies are currently thought to cause chronic metabolic derangement leading to or exacerbating immune deficiencY, gastrointestinal problems, endocrine disorders, neurologic dysfunction, cancer, accelerated aging, degenerative disease, and more. Zn deficiency caused by malnutrition and foods with low bioavailability, aging, certain diseases, or deregulated homeostasis is a far more common risk to human health than intoxication. Higher dose of Zn should be limited to short-term use because of an increased risk of gastrointestinal adverse effects, copper deficiency, anemia, and genitourinary complications. This review has detonated the literature on the spectrum of health effects of Zn status, ranging from symptoms of Zn deficiency to excess exposure.展开更多
文摘Zinc （Zn） deficiencies are currently thought to cause chronic metabolic derangement leading to or exacerbating immune deficiencY, gastrointestinal problems, endocrine disorders, neurologic dysfunction, cancer, accelerated aging, degenerative disease, and more. Zn deficiency caused by malnutrition and foods with low bioavailability, aging, certain diseases, or deregulated homeostasis is a far more common risk to human health than intoxication. Higher dose of Zn should be limited to short-term use because of an increased risk of gastrointestinal adverse effects, copper deficiency, anemia, and genitourinary complications. This review has detonated the literature on the spectrum of health effects of Zn status, ranging from symptoms of Zn deficiency to excess exposure.
