Objective To observe the effects of acupuncture plus spinal manipulations on the physical functioning and levels of alkaline phosphatase(ALP),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and osteoprotege...Objective To observe the effects of acupuncture plus spinal manipulations on the physical functioning and levels of alkaline phosphatase(ALP),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and osteoprotegerin(OPG)in patients with ankylosing spondylitis(AS).Methods A total of 128 AS cases were allocated into a control group and an observation group using random number table method,with 64 cases in each group.Patients in both groups took sulfasalazine and meloxicam.Patients in the observation group received additional acupuncture plus spinal manipulations.The efficacy,Bath AS functional index(BASFI),Bath AS disease activity index(BASDAI),and the levels of ALP,ESR,CRP and OPG were compared between the two groups after eight weeks of treatment.Results After treatment,the symptom scores of traditional Chinese medicine in both groups were decreased(all P<0.05),and these scores in the observation group were significantly lower than in the control group(all P<0.05);the VAS,BASFI and BASDAI scores in both groups were decreased(all P<0.05),and these scores in the observation group were significantly lower than in the control group(all P<0.05);and the ALP,ESR,CRP and OPG levels in both groups were decreased(all P<0.05),and these levels in the observation group were significantly lower than in the control group(all P<0.05).The total efficacy rate was 92.2%in the observation group,versus 78.1%in the control group,presenting a statistical significance(P<0.05).Conclusion Conventional medication combined with acupuncture and spinal manipulations can improve clinical symptoms,accelerate the recovery of physical functioning,and reduce the ALP,ESR,CRP and OPG levels.展开更多
Objective:To observe the efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for hip involvement in ankylosing spondylitis(AS).Methods:A total of 60 patients with hip involvement...Objective:To observe the efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for hip involvement in ankylosing spondylitis(AS).Methods:A total of 60 patients with hip involvement in AS were randomly divided into a control group and an observation group,with 30 cases in each group.The patients in the control group were given an intra-articular injection of sodium hyaluronate,once a week.The patients in the observation group were given additional warm needling moxibustion,once a day,with a 2-day interval after five consecutive days of treatment.After 5 weeks,changes in such indicators as visual analog scale(VAS)score,Harris score,Bath ankylosing spondylitis disease activity index(BASDAI),Bath ankylosing spondylitis functional index(BASFI),serum cartilage oligomeric matrix protein(COMP),interleukin(IL)-17 were observed,and the efficacy was evaluated.Six months after treatment,Bath ankylosing spondylitis radiology index-hip(BASRI-hip)was evaluated.Results:After treatment,the total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the VAS scores in both groups were lower than those before treatment(P<0.05),and the score of the observation group was lower than that of the control group(P<0.05).After treatment,the Harris scores of both groups were higher than those before treatment(P<0.05),and the score of the observation group was higher than that of the control group(P<0.05).Six months after treatment,the BASRI-hip score of the control group was higher than that before treatment(P<0.05),while the score of the observation group was not significantly different from that before treatment(P>0.05)and was lower than that of the control group(P<0.05).After treatment,the scores of BASDAI and BASFI of both groups were lower than those before treatment(P<0.05),and the scores of the observation group were lower than those of the control group(P<0.05).After treatment,the levels of serum COMP and IL-17 of both groups were lower than those before treatment(P<0.05),and the levels of the observation group were lower than those of the control group(P<0.05).Conclusion:The efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for hip involvement in AS is better than the intra-articular injection of sodium hyaluronate alone.This combined approach can alleviate hip pain,improve hip functions,delay the destruction of the hip,prevent AS development,and reduce the levels of serum COMP and IL-17.展开更多
文摘Objective To observe the effects of acupuncture plus spinal manipulations on the physical functioning and levels of alkaline phosphatase(ALP),erythrocyte sedimentation rate(ESR),C-reactive protein(CRP)and osteoprotegerin(OPG)in patients with ankylosing spondylitis(AS).Methods A total of 128 AS cases were allocated into a control group and an observation group using random number table method,with 64 cases in each group.Patients in both groups took sulfasalazine and meloxicam.Patients in the observation group received additional acupuncture plus spinal manipulations.The efficacy,Bath AS functional index(BASFI),Bath AS disease activity index(BASDAI),and the levels of ALP,ESR,CRP and OPG were compared between the two groups after eight weeks of treatment.Results After treatment,the symptom scores of traditional Chinese medicine in both groups were decreased(all P<0.05),and these scores in the observation group were significantly lower than in the control group(all P<0.05);the VAS,BASFI and BASDAI scores in both groups were decreased(all P<0.05),and these scores in the observation group were significantly lower than in the control group(all P<0.05);and the ALP,ESR,CRP and OPG levels in both groups were decreased(all P<0.05),and these levels in the observation group were significantly lower than in the control group(all P<0.05).The total efficacy rate was 92.2%in the observation group,versus 78.1%in the control group,presenting a statistical significance(P<0.05).Conclusion Conventional medication combined with acupuncture and spinal manipulations can improve clinical symptoms,accelerate the recovery of physical functioning,and reduce the ALP,ESR,CRP and OPG levels.
文摘Objective:To observe the efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for hip involvement in ankylosing spondylitis(AS).Methods:A total of 60 patients with hip involvement in AS were randomly divided into a control group and an observation group,with 30 cases in each group.The patients in the control group were given an intra-articular injection of sodium hyaluronate,once a week.The patients in the observation group were given additional warm needling moxibustion,once a day,with a 2-day interval after five consecutive days of treatment.After 5 weeks,changes in such indicators as visual analog scale(VAS)score,Harris score,Bath ankylosing spondylitis disease activity index(BASDAI),Bath ankylosing spondylitis functional index(BASFI),serum cartilage oligomeric matrix protein(COMP),interleukin(IL)-17 were observed,and the efficacy was evaluated.Six months after treatment,Bath ankylosing spondylitis radiology index-hip(BASRI-hip)was evaluated.Results:After treatment,the total effective rate in the observation group was higher than that in the control group(P<0.05).After treatment,the VAS scores in both groups were lower than those before treatment(P<0.05),and the score of the observation group was lower than that of the control group(P<0.05).After treatment,the Harris scores of both groups were higher than those before treatment(P<0.05),and the score of the observation group was higher than that of the control group(P<0.05).Six months after treatment,the BASRI-hip score of the control group was higher than that before treatment(P<0.05),while the score of the observation group was not significantly different from that before treatment(P>0.05)and was lower than that of the control group(P<0.05).After treatment,the scores of BASDAI and BASFI of both groups were lower than those before treatment(P<0.05),and the scores of the observation group were lower than those of the control group(P<0.05).After treatment,the levels of serum COMP and IL-17 of both groups were lower than those before treatment(P<0.05),and the levels of the observation group were lower than those of the control group(P<0.05).Conclusion:The efficacy of warm needling moxibustion plus intra-articular injection of sodium hyaluronate for hip involvement in AS is better than the intra-articular injection of sodium hyaluronate alone.This combined approach can alleviate hip pain,improve hip functions,delay the destruction of the hip,prevent AS development,and reduce the levels of serum COMP and IL-17.
