痛风四妙汤加味治疗痛风性关节炎

目的:观察自拟痛风四妙汤加味治疗痛风性关节炎的临床疗效。方法:运用痛风四妙汤治疗36例中医辨证湿热痰浊痹阻型原发性痛风患者,观察其疗效。结果:治愈14例,显效15例,有效5例,无效2例,总有效率95%。结论:中医药经方加味,辨证论治痛风性关节炎,疗效可靠,副反应少。

四妙痛风汤治疗急性痛风性关节炎的临床研究

目的观察四妙痛风汤治疗急性痛风性关节炎的临床疗效。方法将纳入标准的急性痛风性关节炎患者60例随机分为治疗组30例与对照组30例。治疗组口服中药四妙痛风汤,对照组口服依托考昔片,连续治疗15天为一个疗程。观察治疗前后患者临床症状及实验室指标的变化。结果治疗15 d后,治疗组有效率为86.0%,对照组有效率为83.3%,两组总体疗效无明显差异(P>0.05),且两组患者尿酸、ESR、CRP等指标较治疗前均有明显改善。结论四妙痛风汤治疗急性痛风性关节炎临床疗效确切。

加味四妙汤配合新癀片外敷治疗急性痛风性关节炎34例临床观察

目的:观察加味四妙汤配合新癀片外敷治疗急性痛风性关节炎的临床疗效。方法:选择68例急性痛风性关节炎患者,随机分为观察组和对照组各34例,对照组给予秋水仙碱治疗,观察组采用加味四妙汤配合新癀片外敷治疗。观察两组的治疗效果,对比两组治疗前后尿酸、C反应蛋白及血沉和疼痛评分的变化情况,观察两组治疗期间不良反应情况。结果:治疗后观察组的临床治疗总有效率为97.06%,对照组为79.41%,差异有统计学意义(P<0.05),两组治疗前尿酸、ESR、CRP和VAS评分治疗后均显著降低(P<0.05),且观察组评分均低于对照组(P<0.05),观察组的不良反应发生率均低于对照组(P<0.05)。结论:加味四妙汤配合新癀片外敷治疗急性痛风性关节炎效果更显著,不良反应少。

Treatment of 60 Cases of Gouty Arthritis with Modified Simiao Tang

Objective:To observe the clinical effect of a modified Simiao Tang (加味四妙汤 Modified Decoction of Four Wonderful Drugs) for gouty arthritis and its influence on uric acid in blood. Methods: 120 cases of gouty arthritis were randomly divided into the treatment group and control group with 60 cases in each group. Modified Simiao Tang (MST) was orally administered to the patients in the treatment group and allopurinol tablet was orally administered to the patients in the control group. The clinical effects of two groups were evaluated after one-week treatment and uric acid (UA) and C-reactive protein (CRP) levels in blood were determined after 1-month treatment. Results: The total effective rate in the treatment group was significantly higher than in the control group, 86.7% vs. 68.3% (P< 0.01). And the treatment group was also significantly better than the control group in decreasing UA and CRP (P<0.05 or P<0.01). Conclusions: MST can significantly improve the symptoms and signs of gouty arthritis and decrease the levels of UA and CRP. It is good for gouty arthritis.

中医经典方剂治疗痛风的研究进展

当今世界约有1亿病患深受痛风的困扰,目前主要使用降尿酸类药物和抗炎镇痛类药物预防和治疗痛风的急性发作。中医药在防治痛风方面有着近千年的临床应用经验,涌现出大量治疗痛风的有效方剂。我们通过查阅文献资料,整理并总结了近年来临床使用和研究频次较多的经典方剂(上中下通用痛风汤、四妙方、萆薢渗湿汤、白虎加桂枝汤、宣痹汤和竹叶石膏汤)的抗痛风作用及其可能的机制,以期为中医药防治痛风的实验研究及临床应用提供参考与思路。