目的:研究清热活血化痰法对2型糖尿病空腹血糖(FPG)、餐后血糖(2 h PG)、糖化血红蛋白(Hb A1c)及中医症状评分的影响。方法:选取满足试验标准的我院内分泌科门诊和住院患者200名,按照入组的先后顺序随机分为对照组、治疗组,每组各100例...目的:研究清热活血化痰法对2型糖尿病空腹血糖(FPG)、餐后血糖(2 h PG)、糖化血红蛋白(Hb A1c)及中医症状评分的影响。方法:选取满足试验标准的我院内分泌科门诊和住院患者200名,按照入组的先后顺序随机分为对照组、治疗组,每组各100例,两组均在生活方式干预基础上加服盐酸二甲双胍片,每次500 mg,餐前服用,每日3次,治疗组在生活干预及口服盐酸二甲双胍片基础上,加服复方三黄汤,每日1剂,水煎每日早晚餐后1 h口服,疗程均为12周。比较两组治疗前后FPG、2 h PG、Hb Alc、中医症状评分的差异。结果:治疗组FPG、2 h PG、Hb Alc、中医症状评分较对照组改善明显。结论:清热活血化痰法对2型糖尿病疗效较单独使用盐酸二甲双胍片降糖效果更显著。展开更多
Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experienc...Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experience in “mechanism-syndrome-medicine-prescription” for thyroid cancer.Methods Through Medcase data processing platform, based on Frequent Pattern(FP)-Growth enhanced correlation analysis algorithm, the medical records of Professor ZHOU Zhongying for the treatment of thyroid cancer from June 1, 2001 to February 28, 2015 were analyzed within the set.Results This study involved 43 medical records, 43 patients, and 167 visits. After processing intra-set correlations, 28 groups of highly correlated symptoms, 21 groups of highly correlated tongue images, 10 groups of highly correlated pulse conditions, 28 groups of highly correlated pathogenesis, 34 groups of highly correlated herbs, and 26 groups of highly correlated western medicine diagnosis were selected. Professor ZHOU Zhongying treats thyroid cancer according to syndrome differentiation. Symptoms with more association rules included neck swelling, neck pain, cough, and dry mouth;tongue images with more association rules included dark purple tongue, dark red tongue, and fissured tongue;pulse conditions with more association rules were wiry pulse, thready pulse, small pulse, and slippery pulse;the pathogenesis with more association rules was phlegm and blood stasis, damp-heat accumulation,and impairment of both Qi and Yin;herbs with more association rules were Chaihu(Bupleuri Radix), Zeqi(Sun Euphoribiae Herb), and Tiandong(Asparagi Radix);western medicine diagnosis with more association rules included thyroid cancer, insomnia, and chronic gastritis.Conclusion Thyroid cancer mostly presents as deficiency in origin and excess in manifestations. The basic pathogenesis is phlegm and blood stasis, damp-heat accumulation, and impairment of both Qi and Yin, which are closely related to liver, kidney, and spleen. Professor ZHOU Zhongying adopts both attack and supplement approaches as the general treatment principle, with a strong emphasis on regulating Qi and relieving depression, eliminating phlegm and resolving stagnation, eliminating dampness and turbidity, clearing fire and destroying poison, moistening dryness and softening hard mass, invigorating Qi and nourishing Yin, and paying attention to nourishing liver and kidney, invigorating spleen and stomach,while protecting the heart and lungs.展开更多
文摘目的:研究清热活血化痰法对2型糖尿病空腹血糖(FPG)、餐后血糖(2 h PG)、糖化血红蛋白(Hb A1c)及中医症状评分的影响。方法:选取满足试验标准的我院内分泌科门诊和住院患者200名,按照入组的先后顺序随机分为对照组、治疗组,每组各100例,两组均在生活方式干预基础上加服盐酸二甲双胍片,每次500 mg,餐前服用,每日3次,治疗组在生活干预及口服盐酸二甲双胍片基础上,加服复方三黄汤,每日1剂,水煎每日早晚餐后1 h口服,疗程均为12周。比较两组治疗前后FPG、2 h PG、Hb Alc、中医症状评分的差异。结果:治疗组FPG、2 h PG、Hb Alc、中医症状评分较对照组改善明显。结论:清热活血化痰法对2型糖尿病疗效较单独使用盐酸二甲双胍片降糖效果更显著。
基金Six Talent Peak Projects in Jiangsu Province (RJFW-40)Jiangsu Province “333 High-level Talent Training Project”(2018Ⅲ-0121)+2 种基金Technology Innovation Fund of Science and Technology Enterprises in Jiangsu Province (BC2015022)Representative Project of Intangible Cultural Heritage in Pukou District,Nanjing (PKIX-4)The Construction and Application of Thyroid Disease Differentiation and Treatment Rule Mining and Clinical Decision Support System by Traditional Chinese Medicine Master ZHOU Zhongying (012071003583)。
文摘Objective Based on intra-set correlation analysis, this paper deconstructs the clinical medical records of traditional Chinese medicine(TCM) Master ZHOU Zhongying in treating thyroid cancer, and analyzes the experience in “mechanism-syndrome-medicine-prescription” for thyroid cancer.Methods Through Medcase data processing platform, based on Frequent Pattern(FP)-Growth enhanced correlation analysis algorithm, the medical records of Professor ZHOU Zhongying for the treatment of thyroid cancer from June 1, 2001 to February 28, 2015 were analyzed within the set.Results This study involved 43 medical records, 43 patients, and 167 visits. After processing intra-set correlations, 28 groups of highly correlated symptoms, 21 groups of highly correlated tongue images, 10 groups of highly correlated pulse conditions, 28 groups of highly correlated pathogenesis, 34 groups of highly correlated herbs, and 26 groups of highly correlated western medicine diagnosis were selected. Professor ZHOU Zhongying treats thyroid cancer according to syndrome differentiation. Symptoms with more association rules included neck swelling, neck pain, cough, and dry mouth;tongue images with more association rules included dark purple tongue, dark red tongue, and fissured tongue;pulse conditions with more association rules were wiry pulse, thready pulse, small pulse, and slippery pulse;the pathogenesis with more association rules was phlegm and blood stasis, damp-heat accumulation,and impairment of both Qi and Yin;herbs with more association rules were Chaihu(Bupleuri Radix), Zeqi(Sun Euphoribiae Herb), and Tiandong(Asparagi Radix);western medicine diagnosis with more association rules included thyroid cancer, insomnia, and chronic gastritis.Conclusion Thyroid cancer mostly presents as deficiency in origin and excess in manifestations. The basic pathogenesis is phlegm and blood stasis, damp-heat accumulation, and impairment of both Qi and Yin, which are closely related to liver, kidney, and spleen. Professor ZHOU Zhongying adopts both attack and supplement approaches as the general treatment principle, with a strong emphasis on regulating Qi and relieving depression, eliminating phlegm and resolving stagnation, eliminating dampness and turbidity, clearing fire and destroying poison, moistening dryness and softening hard mass, invigorating Qi and nourishing Yin, and paying attention to nourishing liver and kidney, invigorating spleen and stomach,while protecting the heart and lungs.
