超声乳化白内障吸除术在白内障疾病治疗中的应用效果

目的:探究白内障疾病患者实施超声乳化白内障吸除术治疗的临床效果。方法:将笔者所在医院2018年1月-2019年1月实施手术治疗的60例白内障疾病患者作为研究对象,实施超声乳化白内障吸除术治疗的30例患者为研究组,实施小切口非超生乳化白内障吸除术治疗的30例患者为对照组,分组对比60例患者手术前后角膜散光度、手术后并发症发生情况及手术后生存质量评分。结果:研究组手术后角膜散光度均低于对照组,并发症发生率低于对照组,生存质量高于对照组,差异均有统计学意义(P<0.05)。结论:超声乳化白内障吸除术在白内障疾病患者治疗中对患者临床症状的改善效果更加显著,手术后并发症发生率更低,康复效果更佳,值得进行广泛的推广实践。

双微联合手术治疗合并白内障玻璃体视网膜疾病的疗效

目的:研究2mm微切口白内障超声乳化联合23G微创玻璃体切割手术治疗合并白内障玻璃体视网膜疾病的临床疗效。方法:回顾性分析2013-02/2016-02在本院接受治疗的合并白内障玻璃体视网膜疾病的患者92例99眼的临床基本资料,其中男49例53眼,女43例46眼,平均年龄57.1±1.9岁;患者进行眼球麻醉后行玻璃体切割术结合白内障的超声乳化;观察患者的手术疗效和术中、术后出现的并发症情况。结果:患者联合手术均进行得比较顺利,手术中没有后囊膜发生破裂的患者出现。患者中有7眼使用BSS液进行填充,有46眼注射入硅油,有46眼注射入C_3F_8;有49眼Ⅰ期时放置人工晶状体,有21眼在取出硅油时Ⅱ期放置人工晶状体;患者手术以后视力得到提升的有84眼(85%),视力没有发生变化的有15眼(15%);患者手术后出现的并发症包含一过性高眼压18眼(18%)、前房反应7眼(7%)和角膜水肿8眼(8%)。结论:2mm微切口白内障超声乳化联合23G微创玻璃体切割手术对患者的创伤小、并发症少,是一种安全有效的手术方式。

玻切术联合超声乳化吸出术对玻璃体视网膜疾病合并白内障的疗效分析

目的:分析玻璃体切除联合白内障超声乳化吸出术对玻璃体视网膜疾病合并白内障患者的治疗效果。方法:选取2014-01/2016-11在本院接受治疗的玻璃体视网膜疾病合并白内障患者150例,依据随机数字表法将患者分成两组:联合组(75例)采用玻璃体切除联合白内障超声乳化吸出术;对照组(75例)先进行玻璃体切除术,再进行白内障超声乳化吸出术。术后随访6mo,观察患者视力恢复和眼轴长度变化情况,记录术后并发症情况。结果:治疗后两组患者视力≥0.1人数均有明显提高,与治疗前对比差异均有统计学意义(P<0.05),且联合组患者比例为95%,高于对照组的63%,差异有统计学意义(P<0.05);两组患者手术前后眼轴长度均无明显变化,同组治疗前后及组间对比差异均无统计学意义(P>0.05);联合组患者屈光度向近视发生偏移,对照组屈光度向远视发生偏移,两组预测数值对比差异无统计学意义(P>0.05),实际数值对比差异有统计学意义(P<0.05);联合组患者出现并发症比例为24%,低于对照组(40%),差异有统计学意义(P<0.05)。结论:玻璃体切除联合白内障超声乳化吸出术对玻璃体视网膜疾病合并白内障患者疗效显著,且安全性好。

玻切术联合超声乳化吸出术对玻璃体视网膜疾病合并白内障的疗效分析

目的:探究玻璃体视网膜疾病合并白内障患者运用玻切术联合超声乳化吸出术治疗的临床效果。方法:2017年3月-2019年4月收治玻璃体视网膜疾病合并白内障患者150例,随机分为两组,各75例。观察组采用玻切术联合超声乳化吸出术治疗;对照组首先进行玻切术,再实施超声乳化吸出术治疗。比较两组治疗效果。结果:观察组治疗后视力改善优于对照组,并发症发生率低于对照组,差异有统计学意义(P<0.05)。结论:玻璃体视网膜疾病合并白内障患者运用玻切术联合超声乳化吸出术治疗后,能促进患者视力水平得到明显改善,还可以减少并发症的发生。

Comparison in effect of different metal ions, pH and reducing agent on the protease activity in human hyper mature and mature cataract

This study was undertaken to isolate and characterize the protease activity of human eye lens sample of mature and hyper mature cataract. Samples were collected just after surgery of the cataract lens and were stored at -20 ℃. The total protein extract was isolated from 5 samples in each case （mature and hyper mature cataract） and clear supernatant obtained after centrifugation was used as an enzyme source. The optimum pH for the proteases of mature cataract was 7.5 while the proteases of hyper mature cataract were recorded for maximum activity at pH 5.5 and 7.5. The optimum temperature for both enzyme sources was 50 ℃. Effect of different metal ions such as potassium, lead, silver, zinc and borate was studied. In each case protease activity was increased. Reducing agent e.g. β mercaptoethanol also caused an increase in activity indicating the involvement of sulfhydryl groups. Protease activity was also located on agar plates.

Sensory exotropia subsequent to senile cataract

To evaluate the phacoemulsification and intraocular lens implantation in patients with sensory exotropia subsequent to senile cataract. The authors prospectively studied the role of phacoemulsification and intraocular lens implantation on 25 patients by observing visual acuity, ocular alignment, binocular vision and diplopia pre-, 1 month post- and 3 months post-operation. The patients underwent follow-up for three months. Postoperatively, one patient had a corrected visual acuity of 20/50, and 24 patients had 20/40 or better. The ocular alignment, binocular vision and diplopia were resolved spontaneously. Phacoemulsification and intraocular lens implantation performed together is effective on sensory exotropia subsequent to senile cataract.

The role of Eph receptors in lens function and disease

Cataract is the single largest contributor to blindness in the world,with the disease having a strong genetic component.In recent years the Eph family of receptor tyrosine kinases has been identified as a key regulator in lens clarity.In this review we discuss the roles of the Eph receptors in lens biology and cataract development.