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犬心脏移植围术期血清IL-6、IL-8、TNF-α的变化
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作者 杨邦祥 李羽 《四川医学》 CAS 2008年第1期12-13,共2页
目的探讨犬心脏移植手术中血清白细胞介质6(interleukin-6,IL-6)、白细胞介质8(interleukin-8,IL-8)、肿瘤坏死因子(αtumor necrosis factor-α,TNF-α)浓度的变化。方法20只家犬随机分组配对进行心脏移植手术,分别在麻醉后、转机时、... 目的探讨犬心脏移植手术中血清白细胞介质6(interleukin-6,IL-6)、白细胞介质8(interleukin-8,IL-8)、肿瘤坏死因子(αtumor necrosis factor-α,TNF-α)浓度的变化。方法20只家犬随机分组配对进行心脏移植手术,分别在麻醉后、转机时、停机时、手术结束时取动脉血用酶联免疫吸附法(ELISA)检测受体犬血清中的IL-6I、L-8、TNF-α浓度。结果犬血清IL-6I、L-8、TNF-α浓度在麻醉后持续上升,以停机时和手术结束时更为明显(P<0.05)。结论犬心脏移植手术中存在明显的应激反应和缺血再灌注损伤。 展开更多
关键词 心脏移植 白细胞介质6 白细胞介质8 肿瘤坏死因子Α
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乌司他丁在犬心脏移植手术中对血清IL-6、IL-8、TNF-α影响的观察
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作者 郑雪松 黄滨 《福建医药杂志》 CAS 2011年第3期60-61,共2页
目的探讨犬心脏移植手术中乌司他丁(ulinastatin)对白细胞介质6(interleukin-6,IL-6)、白细胞介质8(interleukin-8,IL-8)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)的影响。方法 32只家犬随机配对分成对照组(C组)和乌司他丁组(... 目的探讨犬心脏移植手术中乌司他丁(ulinastatin)对白细胞介质6(interleukin-6,IL-6)、白细胞介质8(interleukin-8,IL-8)、肿瘤坏死因子α(tumor necrosis factor-α,TNF-α)的影响。方法 32只家犬随机配对分成对照组(C组)和乌司他丁组(U组)进行心脏移植手术,分别在麻醉后(T1)、转机时(T2)、停机时(T3)、手术结束时(T4),取动脉血用酶联免疫吸附法(ELISA)检测受体犬血清中的IL-6、IL-8、TNF-α。结果 U组的IL-6和IL-8从T2开始显著小于C组,U组的TNF-α从T3开始显著小于C组(P<0.05)。结论乌司他丁可以减轻心脏移植手术中的炎症反应。 展开更多
关键词 心脏移植 乌司他丁 白细胞介质6 白细胞介质8 肿瘤坏死因子Α
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EFFECT OF ACUPUNCTURE ON SERUM INTERLUKIN-6 IN WOMEN WITH POSTMENOPAUSAL OSTEOPOROSIS
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作者 李祥炜 王玲玲 刘跃光 《World Journal of Acupuncture-Moxibustion》 2002年第1期24-25,共2页
: To observe the effect of acupuncture on serum interlukin-6 (IL-6) level in women with post-menopausal osteoporosis. Methods: 59 cases of postmenopausal osteoporosis women were randomly divided into acupunctue group(... : To observe the effect of acupuncture on serum interlukin-6 (IL-6) level in women with post-menopausal osteoporosis. Methods: 59 cases of postmenopausal osteoporosis women were randomly divided into acupunctue group(n=32) and calcium D group(n = 27). In acupuncture group, Zusanli (ST 36), Sanyinjiao (SP 6), Shenshu (BL 23) and Pishu (BL 20) were punctured, 3 times every week, continuously for 6 months. In control group, patients were ordered to take Calcium D, one pill (containing 1500 mg calcium carbonate and VitD3) every morning, continuously for 6 months. Serum IL-6 was detected using radioimmunoassay. Results: After six months' treatment, the result showed that in acupuncture group serum IL-6 calcium level lowered while in control group serum IL-6 content increased. Statistical analysis indicates that there are no significant differences between two groups or between pre-treatment and post-treatment in every single group( P > 0.05). Conclusion: Although no statistical difference was found between two groups, acupuncture could decrease secretion of IL-6 in postmenopausal osteoporosis women to a certain degree, refrain the activity of osteoclast and improve the quality of bone. 展开更多
关键词 Acupuncture lnterlukin-6 Postmenopausal osteoporosis
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