Aspects of material selection and innovative concepts of car construction using aluminium as best suited light-weight materials were presented, and recent development in established and advanced use of aluminium in pa...Aspects of material selection and innovative concepts of car construction using aluminium as best suited light-weight materials were presented, and recent development in established and advanced use of aluminium in passenger cars was discussed that help to meet economic and environmental requirements. 5xxx and 6xxx aluminium alloys were presented that have been improved for the increasing demands regarding higher strength and better formability, resulting in a mass reduction and improved crashworthiness. Furthermore, advances concerning multi-material light weight design were presented by examples for aluminium solutions in advanced “Multi-material” Super-Light-Car （SLC） concepts, which reaches significant mass reductions.展开更多
In view of the images collection and processing problems of the smart car camera, the paper introduces a method which deals with field and line synchronization signal separation and binarization processing of the vide...In view of the images collection and processing problems of the smart car camera, the paper introduces a method which deals with field and line synchronization signal separation and binarization processing of the video signal collected from track fields, and which is capable to extract and position black border trajectory images effectively. According to the experiment results of the method, the camera images can be collected and processed effectively, and the accurate image information can be provided for the smart cars to travel along the track. The method has the advantages of being easy to use, strong adaptability, ideal performance and high practical value. On the basis of advantages the method is of high practical value in smart car races.展开更多
OBJECTIVE: To observe the influence of Xinfengcapsule(XFC) on abarticular pathologic changes(APCs) and other indices of patients with rheumatoid arthritis(RA) and explore the mechanism of action of XFC in improving su...OBJECTIVE: To observe the influence of Xinfengcapsule(XFC) on abarticular pathologic changes(APCs) and other indices of patients with rheumatoid arthritis(RA) and explore the mechanism of action of XFC in improving such changes.METHODS: Three-hundred RA patients were divided randomly into a treatment group(n=150) and control group(n=150). A normal control(NC)group(n=90) was also created. Changes in cardiac function, pulmonary function, anemia indices and platelet parameters of RA patients were measured.Curative effects of the two groups were compared,and comparison carried out with the NC group.RESULTS: In 300 RA patients, late diastolic peak flow velocity(A peak) was much higher(P<0.01)and early diastolic peak flow velocity(E peak), E/A,and left ventricular fraction shortening much lower(P<0.01) than those in the NC group. Vital capacity(VC), forced vital capacity in one second, forced vital capacity(FVC), maximal voluntary ventilation(MVV), maximal expiratory flow in 50% of VC(FEF50) and FEF75 were lowered remarkably(P<0.05 or P<0.01). Platelet count(PLT), plateletcrit(PCT) and mean platelet volume(MPV) increased markedly(P<0.05 or P<0.01), and hemoglobin(Hb)level decreased significantly(P<0.05). After XFC treatment, the A peak and PLT and PCT were much lower(P<0.05), and E/A and the number of red blood cells as well as Hb level were much higher(P<0.05), as were FVC, MVV and FEF50(P<0.05 or P<0.01), in the treatment group than those in the NC group. Total score of pain and swelling in joints,uric-acid level and high-sensitivity C-reactive protein level were much lower, and superoxide dismutase level as well as the number of CD4 +CD25+ regulation T cells(Treg) and CD4+CD25+CD127- Treg were much higher(P<0.05 or P<0.01)in the treatment group than those in the NC group.CONCLUSION: RA patients with pathologic changes in joints also suffer from lower cardiac and pulmonary functions and from parameters of anemia and platelet factors. XFC can improve the symptoms of RA patients, ameliorate their cardiac and pulmonary functions and reduce the parameters of anemia and platelet factors. XFC lowers the immune inflammatory reaction to improve APCs in RA patients.展开更多
An improvement was proposed for the statistical theory of breaking erttrainment depth and surface whitecap coverage of real sea waves in this study. The ratio of the kinetic and potential energy was estimated on a the...An improvement was proposed for the statistical theory of breaking erttrainment depth and surface whitecap coverage of real sea waves in this study. The ratio of the kinetic and potential energy was estimated on a theoretical level, and optimal constants were determined to improve the statistical theory model for wave breaking. We also performed a sensitivity test to the model constants. A comparison between the model and in situ observations indicated that the level of agreement was better than has been achieved in previous studies.展开更多
Protein-polymer hybrids consisting of protein and natural polymers or synthetic polymers exhibit superior properties to un- modified proteins, generating a high demand for these materials in the fields of medicine, bi...Protein-polymer hybrids consisting of protein and natural polymers or synthetic polymers exhibit superior properties to un- modified proteins, generating a high demand for these materials in the fields of medicine, biotechnology, and nanotechnology. Herein, protein-polysaccharide hybrids were fabricated via the formation of an amide bond between bovine serum albumin （BSA） and chitosan （CS） using N-ethyl-N-（3-dimethylaminopropyl） carbodiimide hydrochloride （EDC） as the couple reagent. FTIR spectrum reveals that the carboxyl group of BSA conjugated with the amino group of chitosan backbone. The molecular weight of BSA-CS hybrids was identified by matrix-associated laser desorption ionization time of flight mass spectra （MALDI-TOF MS） and sodium dodecyl sulfate polyacrylamide gel electrophoresis （SDS-PAGE）. The maximum number of chitosan chains binding to each BSA molecule was estimated as 6, and the optimal number was estimated as 2. In addition, the secondary structure and surface property of BSA were dependent upon the number of polymer conjugating on protein. The secondary structure of BSA was not significantly changed, if a few chitosans were coupled with BSA. By further increasing the molar ratio of chitosan to BSA, the secondary structure of BSA was markedly damaged. The surface＇s negative charges of modified BSA also decreased. The result of native polyaerylamide gel electrophoresis （native-PAGE） also demonstrated the changes in surface charges and molecular weight of BSA-CS hybrids.展开更多
基金funded project SLC (Sustainable Production Technologies of Emission Reduced Light Weight Car concepts) Proposal/Contract No.: 516465 in the EU 6th Framework Programme the colleagues from the SLC consortium, the European Council of Automotive Research (EUCAR) and the European Aluminium Association (EAA) for their support
文摘Aspects of material selection and innovative concepts of car construction using aluminium as best suited light-weight materials were presented, and recent development in established and advanced use of aluminium in passenger cars was discussed that help to meet economic and environmental requirements. 5xxx and 6xxx aluminium alloys were presented that have been improved for the increasing demands regarding higher strength and better formability, resulting in a mass reduction and improved crashworthiness. Furthermore, advances concerning multi-material light weight design were presented by examples for aluminium solutions in advanced “Multi-material” Super-Light-Car （SLC） concepts, which reaches significant mass reductions.
文摘In view of the images collection and processing problems of the smart car camera, the paper introduces a method which deals with field and line synchronization signal separation and binarization processing of the video signal collected from track fields, and which is capable to extract and position black border trajectory images effectively. According to the experiment results of the method, the camera images can be collected and processed effectively, and the accurate image information can be provided for the smart cars to travel along the track. The method has the advantages of being easy to use, strong adaptability, ideal performance and high practical value. On the basis of advantages the method is of high practical value in smart car races.
基金Supported by the Twelfth Five-Year Support Project of the Ministry of Science and Technology for Clinical Studies Investigating Xin'an Medicine in the Treatment of Complicated Ascites Diseases(No.2012BAI26B02)State Key Discipline Construction Project of TCM:Arthralgia[No.(2009)30]Technology Planning Project of Anhui Science and Technology Department(No.11010402170)
文摘OBJECTIVE: To observe the influence of Xinfengcapsule(XFC) on abarticular pathologic changes(APCs) and other indices of patients with rheumatoid arthritis(RA) and explore the mechanism of action of XFC in improving such changes.METHODS: Three-hundred RA patients were divided randomly into a treatment group(n=150) and control group(n=150). A normal control(NC)group(n=90) was also created. Changes in cardiac function, pulmonary function, anemia indices and platelet parameters of RA patients were measured.Curative effects of the two groups were compared,and comparison carried out with the NC group.RESULTS: In 300 RA patients, late diastolic peak flow velocity(A peak) was much higher(P<0.01)and early diastolic peak flow velocity(E peak), E/A,and left ventricular fraction shortening much lower(P<0.01) than those in the NC group. Vital capacity(VC), forced vital capacity in one second, forced vital capacity(FVC), maximal voluntary ventilation(MVV), maximal expiratory flow in 50% of VC(FEF50) and FEF75 were lowered remarkably(P<0.05 or P<0.01). Platelet count(PLT), plateletcrit(PCT) and mean platelet volume(MPV) increased markedly(P<0.05 or P<0.01), and hemoglobin(Hb)level decreased significantly(P<0.05). After XFC treatment, the A peak and PLT and PCT were much lower(P<0.05), and E/A and the number of red blood cells as well as Hb level were much higher(P<0.05), as were FVC, MVV and FEF50(P<0.05 or P<0.01), in the treatment group than those in the NC group. Total score of pain and swelling in joints,uric-acid level and high-sensitivity C-reactive protein level were much lower, and superoxide dismutase level as well as the number of CD4 +CD25+ regulation T cells(Treg) and CD4+CD25+CD127- Treg were much higher(P<0.05 or P<0.01)in the treatment group than those in the NC group.CONCLUSION: RA patients with pathologic changes in joints also suffer from lower cardiac and pulmonary functions and from parameters of anemia and platelet factors. XFC can improve the symptoms of RA patients, ameliorate their cardiac and pulmonary functions and reduce the parameters of anemia and platelet factors. XFC lowers the immune inflammatory reaction to improve APCs in RA patients.
基金supported by the National High Technology Research and Development Program of China(Grant No.2013AA09A506)the National Natural Science Foundation of ChinaShandong Joint Fund for Marine Science Research Centers(Grant No. U1406404)+2 种基金the Youth Natural Foundation of Shandong Province(Grant No.ZR2015PD009)the Scientific and Technological Innovation Project Financially Supported by Qingdao National Laboratory for Marine Science and Technology(Grant No.2015ASKJ01)the Youth Science Foundation of China-Indonesia Maritime Cooperation Fund(Grant No. YZ0115005)
文摘An improvement was proposed for the statistical theory of breaking erttrainment depth and surface whitecap coverage of real sea waves in this study. The ratio of the kinetic and potential energy was estimated on a theoretical level, and optimal constants were determined to improve the statistical theory model for wave breaking. We also performed a sensitivity test to the model constants. A comparison between the model and in situ observations indicated that the level of agreement was better than has been achieved in previous studies.
基金supported by the National Natural Science Foundation of China (21164003,20964002)the Gansu Sci & Techn Support Project(1011GKCA017)+2 种基金the Fundamental Res. Funds Univ. Gansu Province(2010-176)Lanzhou Science Technology Bureau (2009-1-14)NWNU-kjcxgc-03-63
文摘Protein-polymer hybrids consisting of protein and natural polymers or synthetic polymers exhibit superior properties to un- modified proteins, generating a high demand for these materials in the fields of medicine, biotechnology, and nanotechnology. Herein, protein-polysaccharide hybrids were fabricated via the formation of an amide bond between bovine serum albumin （BSA） and chitosan （CS） using N-ethyl-N-（3-dimethylaminopropyl） carbodiimide hydrochloride （EDC） as the couple reagent. FTIR spectrum reveals that the carboxyl group of BSA conjugated with the amino group of chitosan backbone. The molecular weight of BSA-CS hybrids was identified by matrix-associated laser desorption ionization time of flight mass spectra （MALDI-TOF MS） and sodium dodecyl sulfate polyacrylamide gel electrophoresis （SDS-PAGE）. The maximum number of chitosan chains binding to each BSA molecule was estimated as 6, and the optimal number was estimated as 2. In addition, the secondary structure and surface property of BSA were dependent upon the number of polymer conjugating on protein. The secondary structure of BSA was not significantly changed, if a few chitosans were coupled with BSA. By further increasing the molar ratio of chitosan to BSA, the secondary structure of BSA was markedly damaged. The surface＇s negative charges of modified BSA also decreased. The result of native polyaerylamide gel electrophoresis （native-PAGE） also demonstrated the changes in surface charges and molecular weight of BSA-CS hybrids.
