Scalp care is important in maintaining good conditions of scalp and hair. Key technical approaches for scalp care include reducing the chance of scalp inflammation, improving scalp defense, and activating hair follicl...Scalp care is important in maintaining good conditions of scalp and hair. Key technical approaches for scalp care include reducing the chance of scalp inflammation, improving scalp defense, and activating hair follicle cells. As the cosmetics industry is moving toward to alternative methods to animal testing based on the 3 Rs(Replacement, Reduction and Refinement), in vitro methods will be widely used to evaluate the effects of scalp care. In this paper, we describe the detailed technical approaches for scalp care and the in vitro evaluation methods for skin irritation, anti-inflammation, barrier function, blood circulation, hair growth and male pattern hair loss prevention, respectively.展开更多
Recent articles reviewed the molecular damaging pathway of various pollutants especially PM2.5 particles and polycylic aromatic hydrocarbon. AhR （aryl hydrocarbon receptor） pathway, tobacco-similar pathway, oxidatio...Recent articles reviewed the molecular damaging pathway of various pollutants especially PM2.5 particles and polycylic aromatic hydrocarbon. AhR （aryl hydrocarbon receptor） pathway, tobacco-similar pathway, oxidation, as well as epigenetics pathway were reviewed. Based on the working mechanism, the reported study method and methodology used in Ashland lab were reviewed, including cell level experiment, through reconstructed human skin to in vivo study.展开更多
文摘Scalp care is important in maintaining good conditions of scalp and hair. Key technical approaches for scalp care include reducing the chance of scalp inflammation, improving scalp defense, and activating hair follicle cells. As the cosmetics industry is moving toward to alternative methods to animal testing based on the 3 Rs(Replacement, Reduction and Refinement), in vitro methods will be widely used to evaluate the effects of scalp care. In this paper, we describe the detailed technical approaches for scalp care and the in vitro evaluation methods for skin irritation, anti-inflammation, barrier function, blood circulation, hair growth and male pattern hair loss prevention, respectively.
文摘Recent articles reviewed the molecular damaging pathway of various pollutants especially PM2.5 particles and polycylic aromatic hydrocarbon. AhR （aryl hydrocarbon receptor） pathway, tobacco-similar pathway, oxidation, as well as epigenetics pathway were reviewed. Based on the working mechanism, the reported study method and methodology used in Ashland lab were reviewed, including cell level experiment, through reconstructed human skin to in vivo study.
