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活络止痛汤对模型大鼠皮肤毛细血管通透性的影响 被引量:1
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作者 徐爱良 彭延古 +2 位作者 文宁 曾序求 付灿云 《中国中医药信息杂志》 CAS CSCD 2005年第3期40-41,共2页
目的观察活络止痛汤对类风湿性关节炎的影响。方法将SD大鼠随机分组,用组胺致大鼠背局部皮肤急性炎症模型,静脉注射伊文思蓝后,观察药物对大鼠皮肤毛细血管通透性的影响。结果对大鼠皮肤毛细血管通透性影响的皮肤蓝染面积和吸光度测定... 目的观察活络止痛汤对类风湿性关节炎的影响。方法将SD大鼠随机分组,用组胺致大鼠背局部皮肤急性炎症模型,静脉注射伊文思蓝后,观察药物对大鼠皮肤毛细血管通透性的影响。结果对大鼠皮肤毛细血管通透性影响的皮肤蓝染面积和吸光度测定实验显示,活络止痛汤大剂量组、中剂量组、对照组与空白组比较有显著差异;活络止痛汤大剂量组与对照组、活络止痛汤中剂量组比较有显著差异(P<0.05,P<0.01)。结论活络止痛汤大剂对大鼠皮肤毛细血管通透性模型的抗炎作用显著。 展开更多
关键词 活络止痛汤 类风湿关节炎 大鼠 皮肤毛细血管通透性 抗炎
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四种中草药的抗炎作用 被引量:6
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作者 李培锋 关红 贺春阳 《内蒙古农牧学院学报》 1990年第1期36-39,共4页
腹腔注射金银花、紫花地丁、板兰根煎剂0.5~1.5g/kg,对小白鼠皮肤血管通透性亢进,棉球肉芽增生以及对大白鼠甲醛性足蹠肿胀均有显著的抑制作用:腹腔注射皂刺煎剂0.5~1.5g/kg,对小白鼠棉球芽增生有明显的抑制作用,但对大白鼠甲醛性足... 腹腔注射金银花、紫花地丁、板兰根煎剂0.5~1.5g/kg,对小白鼠皮肤血管通透性亢进,棉球肉芽增生以及对大白鼠甲醛性足蹠肿胀均有显著的抑制作用:腹腔注射皂刺煎剂0.5~1.5g/kg,对小白鼠棉球芽增生有明显的抑制作用,但对大白鼠甲醛性足蹠肿胀的抑制作用发生较慢。 展开更多
关键词 金银花 紫花地丁 板兰根 皂刺 抗炎作用 药理作用 兽药 皮肤毛细血管通透性 棉球肉芽增生 抑制作用
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Distribution and Permeability of Capillaries at the Skin of the Conception Vessel and the Governor Vessel in Healthy Rabbits 被引量:1
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作者 周丹 郭义 +2 位作者 郭永明 张赛 潘萍 《Journal of Traditional Chinese Medicine》 SCIE CAS CSCD 2011年第4期356-359,共4页
Objective: To investigate the distribution and permeability of blood vessels on the Conception Vessel and the Governor Vessel in the physiological state. Methods: Evans blue (EB) solution was injected into the margina... Objective: To investigate the distribution and permeability of blood vessels on the Conception Vessel and the Governor Vessel in the physiological state. Methods: Evans blue (EB) solution was injected into the marginal ear vein of healthy rabbits. Three hours after injection, the rabbits were sacrificed and the skin on the Conception Vessel and the Governor Vessel and the corresponding bilateral non-channels was collected. EB was extracted with 7:3 acetone: physiological saline, and the absorbance of EB at each skin tissue was measured with a spectrophotometer. Results: The A value of EB absorbance at the Conception Vessel on the abdominal skin was lower than that of the corresponding bilateral non-channels with a statistically significant difference (P<0.01). The A value of EB absorbance at the Governor Vessel on the back was higher than that of the corresponding bilateral non-channels (P<0.05). There was no statistical difference in the A value of EB absorbance between the bilateral non-channels of the abdomen and the back (P>0.05). Conclusion: There were differences in capillary distribution and permeability between the Conception Vessel, the Governor Vessel and the corresponding bilateral non-meridians. 展开更多
关键词 the Conception Vessel the Governor Vessel EB content at skin
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