由制革下脚料制皮肥生产工艺及用途的开发

阐述了由制革固体废料制取皮肥的生产工艺及皮肥在农业上的应用。

四肢外科学

9905153 指皮肥厚(Pachydermodactyly)的1例[日]/斋藤昌美∥日形外会志.-1997,17(4).-275 冀医情 9905154 足溃疡伴有骨髓炎1例及本院伴有骨髓炎病例的特征[日]/细川和广∥诊药.-1997,34(9).-42～43 冀医情 9905155 采取足底皮肤的要领[日]/北山稔大∥日形外会志.-1997,17(4).-

Enhanced Growth and Yield Performance of Cassava Peel Compost and Mineral Fertilizer on Corchorus olitorius L.

Application of inorganic fertilizers improves crop yields but costs and adverse health effects often discourage their applications. This study therefore aims at evaluating the combined effects of cassava peel compost with poultry manure and mineral fertilizer on growth and yields of Corchorus olitorius. Pots （factorial laid out in a randomized complete block design） and field （split-plot with fertilizer being the main effect and the varieties the sub plot effect） experiments were carried out during rainy season at Ibadan, Nigeria. Treatments consisted of 0, 5, l0 and 20 t/ha composts prepared from cassava peel and poultry manure in ratio 3：1 and mineral fertilizer （NPK 15：15：15） at the rate of 250 kg/ha, using two varieties of C. olitorius. Five and six weeks after planting （WAP）, plants were assessed for growth and yields in pot and field experiments respectively, and also in residual studies. Application of compost significantly improved growth （heights） （36.50-41.56 cm）, while morphological and dry weight values increased with increase in compost. Marketable yield increase of 13.2%, 22.3%, 32.1% and 29.3% were recorded using 5, 10, 20 t/ha compost and NPK fertilizer respectively in the field. Corresponding increase when ratooned were 40.0%, 42.9%, 57.1% and 52.0%, respectively. Application of compost at the rate of 20 t/ha performed better in the main and residual effect experiments compared to NPK fertilizer and other compost rates. Application of cassavas peels compost at the rate of 20 t/ha proved to be adequate for optimum growth and yield performance of C. olitorius.

INTRACELLULAR REDISTRIBUTION OF CARDIAC ENDOTHELIN- 1 RECEPTOR IN RAT DURING MYOCARDIAL HYPERTROPHY

Objective. In a model of rat cardiac hypertrophy, the changes in the distribution of ET- 1 receptors in two subcellular fractions, the sarcolemma and the light vesicles during myocardial hypertrophy were studied. Methods. Cardiac hypertrophy was produced by placing a constricting clip around the suprarenal abdominal aorta of rats, and ET- 1 receptor was assayed with radioactive analysis method. Results. It was found that plasma and ventricular ET- 1 levels increased significantly on week 2 and week 4 of pressure overload. ET- 1 binding studies showed that during myocardial hypertrophy, the maximum binding capacity (Bmax) was increased by 41％ (P< 0.01) and 65％ (P< 0.01) in sarcolemma in H- 2 week and H- 4 week groups, but was decreased by 24％ (P< 0.01) and 21％ (P< 0.01) in light vesicles. The sum of Bmax of sarcolemmal and light vesicle fractions was increased by 33％ (P< 0.01) and 57％ (P< 0.01) in group H- 2 week and H- 4 week, respectively. Conclusion. ET- 1 receptors in rat heart were externalized from light vesicles to sarcolemma, which may contribute to the development of myocardial hypertrophy.

RELATIONSHIP OF SERUM ADIPONECTIN LEVELS WITH ADIPOSITY, GLUCOCORTICOIDS,LEPTIN AND INSULIN

Objective To investigate the relationship between serum adiponectin levels with adiposity,glucocorticoids, insulin and leptin in Cushing’ s syndrome, obesity and non-obese subjects. Methods The serumadiponectin concentrations were measured in 104 non-obese and 57 overweight or obese subjects byRIA. 15 patients with Cushing’ s syndrome, 10 with obesity and 9 non-obese subjects were investigated, with theirserum adiponectin, glucocorticoids, insulin and leptin levels measured at 8:00, 12:00, 16:00, 20:00, 24:00 and3:00. Dexamethasone suppression tests in both obesity and Cushing’s syndrome were performed at the dose of Img,2mg and 5mg. Results The serum adiponectin concentrations in non-obese were (10. 15 ±6. 33)mg/L in maleand (13. 82 ±6. 09)mg/L in female, and those in overweight or obese ones were (5. 78 ±3. 55)mg/L in male and(8. 13 ± 4. 32) mg/L in female. In both men and women, the fasting adiponectin levels in overweight or obese sub-jects were lower than those of the non-obese ones, and serum adiponectin concentrations were significantly nagetivelycorrelated with BMI, % Fat and waist circumference. The circadian rhythmicity of adiponectin was not distinct, butthe adiponectin levels in obesity were lower than those of the non-obese subjects at all 6 time spots. The serum adi-ponectin area under curve (AUC) were significantly nagetively correlated with BMI, waist circumference and insulinA UC. The adiponectin levels with dexamethasone administration for a short-term both at higher doses and lower do-ses did not change, but was decreased after surgery. Conclusion Adiponectin is a hormone secreted by adipo-cytes which may intimately related to obese and insulin resistance. Therefore, any treatment that could be used to in-crease adiponectin should be beneficial. Neither long-term endogenous hyper-glucocorticoid nor short-term dexam-ethasone administration may affect the adiponectin levels, and similarly, no change with elevated postprandial insu-lin levels.

Complications of percutaneous transluminal septal myocardial ablation in hypertrophic obstructive cardiomyopathy

OBJECTIVE: To assess the complications of percutaneous tansluminal septal myocardial ablation (PTSMA) for the treatment of hypertrophic obstructive cardiomyopathy (HOCM). METHODS: Seventy-two patients with symptomatic left ventricular outflow tract obstruction were diagnosed by echocardiography or catheterization procedures. Absolute ethanol was injected into the target coronary artery branch (branches) for septal myocardial ablation. Documented complications were recorded. RESULTS: Sixty-nine patients had severe chest pain, 19 developed different degrees of heart block during the periprocedural period, but only one developed a complete AV block, requiring permanent pace-maker implantation. Temporary right bundle branch block occurred in 50% of patients and permanent block occurred in 38.9% of patients. Acute inferior myocardial infarction occurred in six patients (8.3%) and acute anterior myocardial infarction occurred in one patient. During two-year follow-up of 24 cases, there were no deaths. All patients had improvement in heart function and none experienced heart failure. CONCLUSION: The most common complication of PTSMA is right bundle branch block. The most significant complication of the procedure is heart block. PTSMA is a good technical, non-surgical treatment for HOCM.

Overweight and obesity versus concentrations of VEGF-A, sVEGFR-1, and sVEGFR-2 in plasma of patients with lower limb chronic ischemia

Objective： Being overweight or obese comprises a significant risk factor for atherosclerosis. Fat tissue also generates factors stimulating angiogenesis, the process by which new blood vessels form. The purpose of this paper is to assess concentrations of the vascular endothelial growth factor A （VEGF-A） and its soluble type-1 and type-2 re- ceptors （sVEGFR-1 and sVEGFR-2） in plasma of patients with peripheral arterial disease （PAD） depending on the level of nutrition according to body mass index （BMI）. Methods： The study group included patients suffering from symptomatic PAD （n=46） in Fontaine classes Ila-lV without any history of neoplastic disease and who have a normal BMI （n=15）, are overweight （n=21） or are obese （n=10）. The control group （n=30） consisted of healthy non-smoking volunteers who were neither overweight nor obese. Venous blood plasma samples were collected from both groups at rest in the morning to determine plasma concentrations of VEGF-A, sVEGFR-1, and sVEGFR-2 using the enzyme- linked immunosorbent assay （ELISA） method. Results： The group of patients with PAD co-existent with being over- weight or obese tended to have higher mean concentration levels of VEGF-A and sVEGFR-2 when compared with patients suffering from PAD with normal BMIo A statistically significant positive correlation was obtained between BMI and average plasma concentrations of sVEGFR-2 （R=0.37, P=-0.0103）. However, no significant correlation was no- ticed between BMI and VEGF-A or sVEGFR-1 concentrations. Conclusions： A positive correlation determined be- tween the level of antiangiogenic factor and BMI value may be indicative of the linearly growing prevalence of some antiangiogenic factors in patients with metabolic disorders, which may be one of numerous factors contributing to incomplete efficiency of collateral circulation development in patients with PAD.