分析城市轨道交通自动售检票系统(A F C系统)运营管理的现状特点,由网络化运营、集中管理条件下AFC系统运营管理需求入手,提出建设城市轨道交通AFC监视中心系统的主要功能,并对系统进行方案设计,设计方案考虑了AFC系统运营管理自身的现...分析城市轨道交通自动售检票系统(A F C系统)运营管理的现状特点,由网络化运营、集中管理条件下AFC系统运营管理需求入手,提出建设城市轨道交通AFC监视中心系统的主要功能,并对系统进行方案设计,设计方案考虑了AFC系统运营管理自身的现状与特点,并及时响应AFC系统运营管理的变化,能够为AFC系统运营管理提供及时有效的管理手段和技术支撑平台.展开更多
OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world a...OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety.展开更多
文摘分析城市轨道交通自动售检票系统(A F C系统)运营管理的现状特点,由网络化运营、集中管理条件下AFC系统运营管理需求入手,提出建设城市轨道交通AFC监视中心系统的主要功能,并对系统进行方案设计,设计方案考虑了AFC系统运营管理自身的现状与特点,并及时响应AFC系统运营管理的变化,能够为AFC系统运营管理提供及时有效的管理手段和技术支撑平台.
基金Sichuan Science and Technology Support Project:the Nested Case-control Study on Adverse Reaction Centralized Monitoring and Risk Factors of Leonurus Japonicus Injection(No.2014ZS0139)the Major State Basic Research Grant(973-program+2 种基金2011CB505406)Ph.D.Programs Foundation of Ministry of Education of China(No.2013-1210110001)State Administration of Traditional Chinese Medicine "Twelve-Five" Focus on Cultivating Subjects of Chinese Preventive Medicine[(2012)170]
文摘OBJECTIVE:To investigate the safety profiles of Motherwort injection(MI).METHODS:A multi-center,prospective and drugderived hospital intensive monitoring method was conducted to assess the safety of MI in real world applications.This study was based on a very large population after the injection was approved and marketed in China.All patients using the injection in participating hospitals were monitored to determine the incidence,pattern,severity and outcome of associated adverse events.RESULTS:The post-marketing surveillance was performed in 10 094 female patients from April to December,2015.The incidence of adverse drug reactions(ADRs) was 0.79‰(8/10 094).Among the 8 patients,the reported adverse events mainly included systemic abnormalities,such as fever,chills and eyelid edema;skin and appendages disorders,such as pruritus and rash;gastrointestinal disorders,such as nausea,abdominal distension and pain;heart rate and rhythm disorders,such as palpitation and increased heart rate.All of these ADRs were mild in severity.CONCLUSION:In this study the ADRs incidence rate of MI is very low,which supports that it is generally safe for use in obstetric and gynecological diseases.However,the total number of 8 ADRs recorded over a relatively short time span seems limited,and the low number of reports could not represent an absolute guarantee of safety.