Purpose: To evaluate changes in lens opacity in the first year after prophylactic laser peripheral iridotomy (LPI) performed in fellow eyes of subjects with acute primary angle closure (APAC). Design: Prospective obse...Purpose: To evaluate changes in lens opacity in the first year after prophylactic laser peripheral iridotomy (LPI) performed in fellow eyes of subjects with acute primary angle closure (APAC). Design: Prospective observational case series. Participants: Sixty Asian subjects with unilateral APAC. Methods: All fellow eyes underwent prophylactic LPI within the first week of presentation, followed by 1 week of topical steroids. The degree of lens opacity was graded at the slit-lamp examination using the Lens Opacity Classification System III (LOCS III) with standard color photographs as the reference for grading of lens opacity. This was performed 2 weeks, 4 months, and 12 months after LPI. Progression in lens opacity was defined as an increase in LOCS III grade by 2 or more units in any lens region. Main Outcome Measures: Lens Opacity Classification Sytem III grades in nuclear, cortical, and posterior subcapsular (PSC) regions. Results: Most patients were Chinese (85% ) and female (63.3% ), with an average age of 61.5 ± 10.6 years. The mean baseline LOCS grades in the nuclear, cortical, and PSC regions were 3.58 ± 0.74, 0.57 ± 1.08, and 0.23 ± 0.72, respectively. With 12 months of follow-up, 14 of the 60 eyes (23.3% ; 95% confidence interval, 16.9- 29.7% ) showed signifi-cant progression in any lens region. Progression in the nuclear, cortical, and PSC regions was documented in 5% , 6.7% , and 16.7% of cases, respectively. By use of logistic regression, the following factors were not found to be significant for cataract progression in any lens region: age, race, gender, history of hypertension or diabetes, presence of peripheral anterior synechiae or angle width at baseline, and total laser energy delivered. Conclusions: In fellow eyes of APAC, prophylactic LPI is complicated by significant cataract progression, mainly in the posterior subcapsular region. These findings may have implications for the role of prophylactic LPI in the prevention of angle-closure blindness.展开更多
In order to improve the performance of the existing phase frequency detectors （PFDs）, a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparison...In order to improve the performance of the existing phase frequency detectors （PFDs）, a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparisons are made. A new robust CMOS phase frequency detector for a high speed and low jitter charge pump phrase-locked loop （PLL） is designed. The proposed PFD consists of two rising-edge triggered dynamic D flip-flops, two positive-edge detectors and delaying units and two OR gates. It adopts two reset mechanisms to avoid the LIP and DN signals to be logic-1 simultaneously. Thus, any current mismatch of the charge pump circuit will not worsen the performance of the PLL. Furthermore, it has hardly any dead-zone phenomenon in phase characteristic. Simulations with ADS are performed based on a TSMC 0. 18-μm CMOS process with a 1.8-V supply voltage. According to the theoretical analyses and simulation results, the proposed PFD shows a satisfactory performance with a high operation frequency （≈ 1 GHz）, a wide phase-detection range [ ± 2π], a near zero dead-zone （ 〈 0. 1 ps）, high reliability, low phase jitter, low power consumption （ ≈100 μW） and small circuit complexity.展开更多
In airborne tracking,the blind Doppler makes the target undetectable,resulting in tracking difficulties. In this paper,we studied most possible blind-Doppler cases and summed them up into two types:targets' intent...In airborne tracking,the blind Doppler makes the target undetectable,resulting in tracking difficulties. In this paper,we studied most possible blind-Doppler cases and summed them up into two types:targets' intentional tangential flying to radar and unintentional flying with large tangential speed. We proposed an interacting multiple model(IMM) particle filter which combines a constant velocity model and an acceleration model to handle maneuvering motions. We compared the IMM particle filter with a previous particle filter solution. Simulation results showed that the IMM particle filter outperforms the method in previous works in terms of tracking accuracy and continuity.展开更多
The message blinding method is the most efficient and secure countermeasure against first-order differential power analysis(DPA).Although cross correlation attacks(CCAs) were given for defeating message blinding metho...The message blinding method is the most efficient and secure countermeasure against first-order differential power analysis(DPA).Although cross correlation attacks(CCAs) were given for defeating message blinding methods,however searching for correlation points is difficult for noise,misalignment in practical environment.In this paper,we propose an optimized cross correlation power attack for message blinding exponentiation algorithms.The attack method can select the more correlative power points of share one operation in the modular multiplication by comparing variances between correlation coefficients.Further we demonstrate that the attack method is more efficient in experiments with hardware implementation of RSA on a crypto chip card.In addition to the proposed CCA method can recovery all 1024 bits secret key and recognition rate increases to 100%even when the recorded signals are noisy.展开更多
In order to alleviate the shortcomings of most blind deconvolution algorithms,this paper proposes an improved fast algorithm for blind deconvolution based on decorrelation technique and broadband block matrix.Althougt...In order to alleviate the shortcomings of most blind deconvolution algorithms,this paper proposes an improved fast algorithm for blind deconvolution based on decorrelation technique and broadband block matrix.Althougth the original algorithm can overcome the shortcomings of current blind deconvolution algorithms,it has a constraint that the number of the source signals must be less than that of the channels.The improved algorithm deletes this constraint by using decorrelation technique.Besides,the improved algorithm raises the separation speed in terms of improving the computing methods of the output signal matrix.Simulation results demonstrate the validation and fast separation of the improved algorithm.展开更多
Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able ...Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able to be executed naturally.Therefore,an effective retinal prosthesis device may be developed by mimicking the function of outer retina:transferring the visual light into artificial stimulus and delivering the stimulus to the retina aiming to evoke the neural responses.As two main developing directions for current retinal prosthesis,epiretinal(ER)and subretinal(SR)prosthesis are both undergoing experimental stage and possessing advantages and limitations.Further investigations in power supply,biocompatibility,etc.are still required.Additionally,suprachoroidal transretinal stimulation(STS)and neurotransmitter-induced stimulation as some other alternatives in retinal prosthesis are also considered as promising research directions,although they are not mature enough to be applied commercially,either.展开更多
We propose a novel flow measurement method for gas–liquid two-phase slug flow by using the blind source separation technique. The flow measurement model is established based on the fluctuation characteristics of diff...We propose a novel flow measurement method for gas–liquid two-phase slug flow by using the blind source separation technique. The flow measurement model is established based on the fluctuation characteristics of differential pressure(DP) signals measured from a Venturi meter. It is demonstrated that DP signals of two-phase flow are a linear mixture of DP signals of single phase fluids. The measurement model is a combination of throttle relationship and blind source separation model. In addition, we estimate the mixture matrix using the independent component analysis(ICA) technique. The mixture matrix could be described using the variances of two DP signals acquired from two Venturi meters. The validity of the proposed model was tested in the gas–liquid twophase flow loop facility. Experimental results showed that for most slug flow the relative error is within 10%.We also find that the mixture matrix is beneficial to investigate the flow mechanism of gas–liquid two-phase flow.展开更多
文摘Purpose: To evaluate changes in lens opacity in the first year after prophylactic laser peripheral iridotomy (LPI) performed in fellow eyes of subjects with acute primary angle closure (APAC). Design: Prospective observational case series. Participants: Sixty Asian subjects with unilateral APAC. Methods: All fellow eyes underwent prophylactic LPI within the first week of presentation, followed by 1 week of topical steroids. The degree of lens opacity was graded at the slit-lamp examination using the Lens Opacity Classification System III (LOCS III) with standard color photographs as the reference for grading of lens opacity. This was performed 2 weeks, 4 months, and 12 months after LPI. Progression in lens opacity was defined as an increase in LOCS III grade by 2 or more units in any lens region. Main Outcome Measures: Lens Opacity Classification Sytem III grades in nuclear, cortical, and posterior subcapsular (PSC) regions. Results: Most patients were Chinese (85% ) and female (63.3% ), with an average age of 61.5 ± 10.6 years. The mean baseline LOCS grades in the nuclear, cortical, and PSC regions were 3.58 ± 0.74, 0.57 ± 1.08, and 0.23 ± 0.72, respectively. With 12 months of follow-up, 14 of the 60 eyes (23.3% ; 95% confidence interval, 16.9- 29.7% ) showed signifi-cant progression in any lens region. Progression in the nuclear, cortical, and PSC regions was documented in 5% , 6.7% , and 16.7% of cases, respectively. By use of logistic regression, the following factors were not found to be significant for cataract progression in any lens region: age, race, gender, history of hypertension or diabetes, presence of peripheral anterior synechiae or angle width at baseline, and total laser energy delivered. Conclusions: In fellow eyes of APAC, prophylactic LPI is complicated by significant cataract progression, mainly in the posterior subcapsular region. These findings may have implications for the role of prophylactic LPI in the prevention of angle-closure blindness.
文摘In order to improve the performance of the existing phase frequency detectors （PFDs）, a systematical analysis of the existing PFDs is presented. Based on the circuit architecture, both classifications and comparisons are made. A new robust CMOS phase frequency detector for a high speed and low jitter charge pump phrase-locked loop （PLL） is designed. The proposed PFD consists of two rising-edge triggered dynamic D flip-flops, two positive-edge detectors and delaying units and two OR gates. It adopts two reset mechanisms to avoid the LIP and DN signals to be logic-1 simultaneously. Thus, any current mismatch of the charge pump circuit will not worsen the performance of the PLL. Furthermore, it has hardly any dead-zone phenomenon in phase characteristic. Simulations with ADS are performed based on a TSMC 0. 18-μm CMOS process with a 1.8-V supply voltage. According to the theoretical analyses and simulation results, the proposed PFD shows a satisfactory performance with a high operation frequency （≈ 1 GHz）, a wide phase-detection range [ ± 2π], a near zero dead-zone （ 〈 0. 1 ps）, high reliability, low phase jitter, low power consumption （ ≈100 μW） and small circuit complexity.
基金Project supported by China Postdoctoral Science Foundation (No.20060400313)partly by Zhejiang Postdoctoral Science Founda-tion of China (No. 2006-bsh-25)
文摘In airborne tracking,the blind Doppler makes the target undetectable,resulting in tracking difficulties. In this paper,we studied most possible blind-Doppler cases and summed them up into two types:targets' intentional tangential flying to radar and unintentional flying with large tangential speed. We proposed an interacting multiple model(IMM) particle filter which combines a constant velocity model and an acceleration model to handle maneuvering motions. We compared the IMM particle filter with a previous particle filter solution. Simulation results showed that the IMM particle filter outperforms the method in previous works in terms of tracking accuracy and continuity.
基金supported in part by National Natural Science Foundation of China Project(Grant No.60873216) Scientific and Technological Research Priority Projects of Sichuan Province(Grant No. 2012GZ0017)
文摘The message blinding method is the most efficient and secure countermeasure against first-order differential power analysis(DPA).Although cross correlation attacks(CCAs) were given for defeating message blinding methods,however searching for correlation points is difficult for noise,misalignment in practical environment.In this paper,we propose an optimized cross correlation power attack for message blinding exponentiation algorithms.The attack method can select the more correlative power points of share one operation in the modular multiplication by comparing variances between correlation coefficients.Further we demonstrate that the attack method is more efficient in experiments with hardware implementation of RSA on a crypto chip card.In addition to the proposed CCA method can recovery all 1024 bits secret key and recognition rate increases to 100%even when the recorded signals are noisy.
基金Natural Science Fund of Anhui Province of China (050420101)
文摘In order to alleviate the shortcomings of most blind deconvolution algorithms,this paper proposes an improved fast algorithm for blind deconvolution based on decorrelation technique and broadband block matrix.Althougth the original algorithm can overcome the shortcomings of current blind deconvolution algorithms,it has a constraint that the number of the source signals must be less than that of the channels.The improved algorithm deletes this constraint by using decorrelation technique.Besides,the improved algorithm raises the separation speed in terms of improving the computing methods of the output signal matrix.Simulation results demonstrate the validation and fast separation of the improved algorithm.
文摘Retinal degenerative diseases may induce the degeneration of outer retina and in turn,blindness.Nevertheless,due to the maintenance of inner retina,the coding and processing of visual neurons responses are still able to be executed naturally.Therefore,an effective retinal prosthesis device may be developed by mimicking the function of outer retina:transferring the visual light into artificial stimulus and delivering the stimulus to the retina aiming to evoke the neural responses.As two main developing directions for current retinal prosthesis,epiretinal(ER)and subretinal(SR)prosthesis are both undergoing experimental stage and possessing advantages and limitations.Further investigations in power supply,biocompatibility,etc.are still required.Additionally,suprachoroidal transretinal stimulation(STS)and neurotransmitter-induced stimulation as some other alternatives in retinal prosthesis are also considered as promising research directions,although they are not mature enough to be applied commercially,either.
基金Supported by the National Natural Science Foundation of China(51304231)the Natural Science Foundation of Shandong Province(ZR2010EQ015)
文摘We propose a novel flow measurement method for gas–liquid two-phase slug flow by using the blind source separation technique. The flow measurement model is established based on the fluctuation characteristics of differential pressure(DP) signals measured from a Venturi meter. It is demonstrated that DP signals of two-phase flow are a linear mixture of DP signals of single phase fluids. The measurement model is a combination of throttle relationship and blind source separation model. In addition, we estimate the mixture matrix using the independent component analysis(ICA) technique. The mixture matrix could be described using the variances of two DP signals acquired from two Venturi meters. The validity of the proposed model was tested in the gas–liquid twophase flow loop facility. Experimental results showed that for most slug flow the relative error is within 10%.We also find that the mixture matrix is beneficial to investigate the flow mechanism of gas–liquid two-phase flow.
