目的:探究急性出血性直肠溃疡综合征(AHRUS)临床特点及内镜下组织胶注射治疗效果。方法:报告青岛大学附属医院消化内科收治的1例急性出血性直肠溃疡综合征的病例,回顾性分析该患者的临床及内镜下特点,及其内镜下治疗结果。结果:患者为...目的:探究急性出血性直肠溃疡综合征(AHRUS)临床特点及内镜下组织胶注射治疗效果。方法:报告青岛大学附属医院消化内科收治的1例急性出血性直肠溃疡综合征的病例,回顾性分析该患者的临床及内镜下特点,及其内镜下治疗结果。结果:患者为中年女性,便血1周急诊入院,失血较多呈昏迷状态,血红蛋白71 g/L,内镜下表现为急性出血性多发直肠溃疡,经药物保守治疗后仍出血不止,给予急诊内镜下组织胶注射止血成功,随访1年半均未再出血。结论:急性出血性直肠溃疡综合征在临床工作中虽少见但病情危重,多以局部对症治疗为主,本例患者内镜下组织胶注射止血效果好,痛苦少,内镜下治疗对AHRUS患者的临床转归具有非常重要的意义。Objective: To explore the clinical features of acute hemorrhagic rectal ulcer syndrome (AHRUS) and the therapeutic effect of endoscopic tissue glue injection. Methods: A case of acute hemorrhagic rectal ulcer syndrome admitted to the Department of Gastroenterology, Affiliated Hospital of Qingdao University was reported. The clinical and endoscopic characteristics of the patient and the results of endoscopic treatment were retrospectively analyzed. Results: The patient was a middle-aged female with hematochezia for one week and was admitted to the emergency hospital in a coma with heavy blood loss and hemoglobin of 71 g/L. The patient showed acute hemorrhagic multiple rectal ulcers under the endoscope, and the bleeding continued after conservative treatment with drugs. The hemostasis was successfully stopped by the injection of tissue glue under the emergency endoscope, and no further bleeding occurred during the follow-up of one and a half years. Conclusion: Although acute hemorrhagic rectal ulcer syndrome is rare in clinical work, the condition is critical, and local symptomatic treatment is mainly used. In this case, endoscopic tissue glue injection has good hemostatic effect and less pain, and endoscopic treatment is of great significance for the clinical outcome of patients with AHRUS.展开更多
目的总结突发无痛性大量便血的卧床患者的临床资料,以期为临床诊治提供参考。方法本研究纳入分析的患者便血出血量大于400 m L,卧床时间为7 d及以上。本院2010年1月至2020年12月诊治的符合研究纳入条件的患者共45例,收集其临床资料,进...目的总结突发无痛性大量便血的卧床患者的临床资料,以期为临床诊治提供参考。方法本研究纳入分析的患者便血出血量大于400 m L,卧床时间为7 d及以上。本院2010年1月至2020年12月诊治的符合研究纳入条件的患者共45例,收集其临床资料,进行回顾性分析并按照出血原因的不同进行归类整理。结果粪性溃疡26例,包括19例多发溃疡、7例单发溃疡,患者平均年龄为(68.3±14.6)岁,中位卧床时间为12.0(9.0,19.3)d,使用抗凝、抗血小板药物的有12例。急性出血性直肠溃疡综合征(AHRUS)15例,包括6例多发溃疡、9例单发溃疡,患者平均年龄为(65.7±11.5)岁,中位卧床时间为10(8,17)d,使用抗凝、抗血小板药物的有7例。粪性溃疡、AHRUS患者采用电子结肠镜下钛夹夹闭止血、经肛门缝合结扎止血或(电子结肠镜下电凝后)凡士林纱布填塞压迫止血等方式处理后,出血完全控制。异物损伤2例,考虑原因分别为开塞露操作不当、灌肠操作,经肛门缝合结扎止血后出血得以控制。直肠憩室1例,予以蛇毒血凝酶灌肠、凡士林纱布填塞压迫止血后出血得以控制。直肠癌1例,予蛇毒血凝酶灌肠、凡士林纱布填塞压迫止血后症状好转,后由于直肠癌基础疾病,患者家属放弃进一步治疗,患者死亡。结论临床中应对突发无痛性大量便血予以足够重视,早期发现并积极处理对患者的临床转归具有重要的意义。对于老年卧床患者、合并严重基础疾病的卧床患者,要注意考虑粪性溃疡、AHRUS的可能。展开更多
文摘目的:探究急性出血性直肠溃疡综合征(AHRUS)临床特点及内镜下组织胶注射治疗效果。方法:报告青岛大学附属医院消化内科收治的1例急性出血性直肠溃疡综合征的病例,回顾性分析该患者的临床及内镜下特点,及其内镜下治疗结果。结果:患者为中年女性,便血1周急诊入院,失血较多呈昏迷状态,血红蛋白71 g/L,内镜下表现为急性出血性多发直肠溃疡,经药物保守治疗后仍出血不止,给予急诊内镜下组织胶注射止血成功,随访1年半均未再出血。结论:急性出血性直肠溃疡综合征在临床工作中虽少见但病情危重,多以局部对症治疗为主,本例患者内镜下组织胶注射止血效果好,痛苦少,内镜下治疗对AHRUS患者的临床转归具有非常重要的意义。Objective: To explore the clinical features of acute hemorrhagic rectal ulcer syndrome (AHRUS) and the therapeutic effect of endoscopic tissue glue injection. Methods: A case of acute hemorrhagic rectal ulcer syndrome admitted to the Department of Gastroenterology, Affiliated Hospital of Qingdao University was reported. The clinical and endoscopic characteristics of the patient and the results of endoscopic treatment were retrospectively analyzed. Results: The patient was a middle-aged female with hematochezia for one week and was admitted to the emergency hospital in a coma with heavy blood loss and hemoglobin of 71 g/L. The patient showed acute hemorrhagic multiple rectal ulcers under the endoscope, and the bleeding continued after conservative treatment with drugs. The hemostasis was successfully stopped by the injection of tissue glue under the emergency endoscope, and no further bleeding occurred during the follow-up of one and a half years. Conclusion: Although acute hemorrhagic rectal ulcer syndrome is rare in clinical work, the condition is critical, and local symptomatic treatment is mainly used. In this case, endoscopic tissue glue injection has good hemostatic effect and less pain, and endoscopic treatment is of great significance for the clinical outcome of patients with AHRUS.
文摘目的总结突发无痛性大量便血的卧床患者的临床资料,以期为临床诊治提供参考。方法本研究纳入分析的患者便血出血量大于400 m L,卧床时间为7 d及以上。本院2010年1月至2020年12月诊治的符合研究纳入条件的患者共45例,收集其临床资料,进行回顾性分析并按照出血原因的不同进行归类整理。结果粪性溃疡26例,包括19例多发溃疡、7例单发溃疡,患者平均年龄为(68.3±14.6)岁,中位卧床时间为12.0(9.0,19.3)d,使用抗凝、抗血小板药物的有12例。急性出血性直肠溃疡综合征(AHRUS)15例,包括6例多发溃疡、9例单发溃疡,患者平均年龄为(65.7±11.5)岁,中位卧床时间为10(8,17)d,使用抗凝、抗血小板药物的有7例。粪性溃疡、AHRUS患者采用电子结肠镜下钛夹夹闭止血、经肛门缝合结扎止血或(电子结肠镜下电凝后)凡士林纱布填塞压迫止血等方式处理后,出血完全控制。异物损伤2例,考虑原因分别为开塞露操作不当、灌肠操作,经肛门缝合结扎止血后出血得以控制。直肠憩室1例,予以蛇毒血凝酶灌肠、凡士林纱布填塞压迫止血后出血得以控制。直肠癌1例,予蛇毒血凝酶灌肠、凡士林纱布填塞压迫止血后症状好转,后由于直肠癌基础疾病,患者家属放弃进一步治疗,患者死亡。结论临床中应对突发无痛性大量便血予以足够重视,早期发现并积极处理对患者的临床转归具有重要的意义。对于老年卧床患者、合并严重基础疾病的卧床患者,要注意考虑粪性溃疡、AHRUS的可能。