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含直链烷酸功能基的5-氟尿嘧啶衍生物的合成
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作者 许刘华 翁玲玲 郑虎 《四川大学学报(医学版)》 CAS CSCD 北大核心 2006年第4期644-646,共3页
目的合成含2~5个碳的直链烷酸功能基的5-氟尿嘧啶衍生物。方法用卤代酸酯和过量的5-氟尿嘧啶(5-FU)反应,再水解得5-FU的N1-位取代直链烷酸。先将5-FU的N1-位用叔丁氧羰基(Boc)保护,再与卤代酸酯反应,最后升温去保护,三步反应... 目的合成含2~5个碳的直链烷酸功能基的5-氟尿嘧啶衍生物。方法用卤代酸酯和过量的5-氟尿嘧啶(5-FU)反应,再水解得5-FU的N1-位取代直链烷酸。先将5-FU的N1-位用叔丁氧羰基(Boc)保护,再与卤代酸酯反应,最后升温去保护,三步反应一锅煮,可得到高收率(75%~85%)的N3-位取代酸酯,水解后得N3-位取代的直链烷酸。结果共合成了5-FU衍生物16个,其中新化合物10个,目标物8个。所有化合物都通过了光谱确证。结论过量的5-FU与卤代酸酯反应能得到较好收率的N1-位单取代物。通过对5-FU的N1-位Boc保护,再与卤代酸酯反应,去保护、水解后可以得到N3-位单取代直链烷酸。 展开更多
关键词 化学合成 5-氟尿嘧啶 直链烷酸 叔丁氧羰基 保护基
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Studies on Degradation Characteristic of LAS High-resistance Strain 被引量:3
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作者 陈宏伟 朱蕴兰 +4 位作者 苏贤岩 邵影 梁峙 曹泽红 林进 《Agricultural Science & Technology》 CAS 2007年第3期33-37,共5页
A IAS degradation strain with high resistance, which could take linear alkylbenzene sulphonate (LAS) as only carton origin for growth, was isolated from the drain canal of Hangao Detergent Plant of Xuzhou. The chara... A IAS degradation strain with high resistance, which could take linear alkylbenzene sulphonate (LAS) as only carton origin for growth, was isolated from the drain canal of Hangao Detergent Plant of Xuzhou. The characteristic of its degradation was researched and the results showed that the optimum conditions of this strain for degrading LAS were 30℃, pH 6.0, 150 ml solution in 500 ml triangle vase, 120 r/min, LAS concentration of 200 - 600 mg/L. The growth amount of the bacteria were up to 0. 443 ( OD400 ) and the degrading rate was up to 89.4%. The ability of the bacterium to degrade LAS could be as high as concentration of 1 200 mg/L. 展开更多
关键词 Linear alkylbenzene sulphonate (LAS) SURFACTANT Degradation strain ISOLATION BIODEGRADATION
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Effects of Self-purification of River Water on Laundry Wastewater
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作者 Liya TAN Yili CHEN +4 位作者 Liuying CHEN Linghan ZENG Yujie CAI Bingbing FENG Hai WANG 《Agricultural Science & Technology》 CAS 2017年第6期1023-1028,共6页
[Objective] This study was conducted to investigate the effect of laundry wastewater on the quality of river water and the dilution purification effect of river water on laundry wastewater. [Method] The effects of lau... [Objective] This study was conducted to investigate the effect of laundry wastewater on the quality of river water and the dilution purification effect of river water on laundry wastewater. [Method] The effects of laundry wastewater on the contents of total nitrogen(TN), total phosphorus(TP), suspended solids(SS), chemical oxygen demand(COD) and linear alkylbenzene sulfonic acid(LAS) were studied in 7 rivers of Shaoxing City. [Result](1) The contents of TN, TP, SS, COD and LAS increased by 92%, 99%, 340%, 351% and 923%, respectively, at the discharging moment of laundry wastewater; and(2) the five pollutional indexes significantly decreased over time, and especially 2 h after the discharge of laundry wastewater, compared with former the discharge of laundry wastewater, the contents of TN, TP, COD and LAS increased by 6%, 11%, 9% and13%, respectively,while the contents of SS still increased by 76%, i.e., SS required a longer time to achieve self-purification. [Conclusion] Laundry wastewater has some influence on thequality of river water, and the self-purification function of river water could effectively remove pollutants. 展开更多
关键词 Laundry wastewater SELF-PURIFICATION Total nitrogen Total phosphorus Linear alkylbenzene sulphonic acid
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Structural Analysis of Hydroxamate Reagents by X-Ray Diffraction 被引量:1
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作者 Ratan Chowdhury Frank Antolasic 《Journal of Earth Science and Engineering》 2012年第10期584-589,共6页
Axis House manufactures and supplies alkyl hydroxamate reagent of various carbon chain lengths for application in flotation of oxide copper and other minerals. As a part of reagent performance improvement, the structu... Axis House manufactures and supplies alkyl hydroxamate reagent of various carbon chain lengths for application in flotation of oxide copper and other minerals. As a part of reagent performance improvement, the structural factors of hydroxamate are examined by various analytical tools in particular with X-ray diffraction of single crystals. In a recent publication, the structures of n-octyl hydroxamic acid and its corresponding potassium salt are presented with findings of hydroxamic functional group geometric preference, H-bonding, keto-enol tautomerisation, acid-salt aggregation and alignment of carbon chain. In this paper, an example of branched alkyl hydroxamate3,5,5-trimethyl hexyl hydroxamate. hydroxamate is presented and compared with the result of linear alkyl 展开更多
关键词 Alkyl hydroxamic acid potassium alkyl hydroxamate X-ray crystal structures flotation of oxide copper minerals.
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