Objective: To observe the electrocardiogram (ECG) and heart rate in a rabbit model ofhyperkalemia induced by potassium chloride, and provide theoretical and experimental reference for timely diagnosis of hyperkalem...Objective: To observe the electrocardiogram (ECG) and heart rate in a rabbit model ofhyperkalemia induced by potassium chloride, and provide theoretical and experimental reference for timely diagnosis of hyperkalemia clinically. Methods: Forty rabbits were randomly assigned into four groups. 0.9% isotonic saline solution was perfused in the group I , while 1.0%, 4.0% and 10.0% potassium chloride solutions were perfused in the other groups, respectively, to induce hyperkalemia. Results: The changes of serum potassium, ECG and heart rate before perfusion were significantly (P〈 0.05) different from those after perfusion in the other groups compared with group I . The effect of ECG variability rates was well consistent (Kappa = 0.724, P〈0.01) with that of serum potassium on diagnostic tests in the other groups. The area under ROC curve in diagnosis effect of ECG variability rates and sermn potassium on hyperkalaemia was much significantly larger (P〈0.01 and P〈0.05) compared with 0.5. There was asignificantly positive correlation between ECG variability rates and serum potassium (r= 0.865, P〈0.05 for bilateral Pearson test). There was certain positive correlation between heart rate and serum potassium, but the correlation was poor (r= 0.526, R2=0.277). Conclusion: A combination of serum potassium, ECG variability rates and heart rate should be considered and analyzed by synthesis to establish an accurate and timely diagnosis for hyperkalemia.展开更多
We study the geometry and the period map of nodal complex prime Fano threefolds with index 1 and degree 10.We show that these threefolds are birationally isomorphic to Verra threefolds,i.e.,hypersurfaces of bidegree (...We study the geometry and the period map of nodal complex prime Fano threefolds with index 1 and degree 10.We show that these threefolds are birationally isomorphic to Verra threefolds,i.e.,hypersurfaces of bidegree (2,2) in P2 × P2.Using Verra's results on the period map for these threefolds and on the Prym map for double tale covers of plane sextic curves,we prove that the fiber of the period map for our nodal threefolds is the union of two disjoint surfaces,for which we give several descriptions.This result is the analog in the nodal case of a result of Debarre O,Iliev A,Manivel L (arXiv:0812.3670) in the smooth case.展开更多
基金Supported by Natural Science Foundation of Chengdu Medical College(CYZ09-004)The "Challenge Cup" Sichuan Undergraduate Curricular Academic Science and Technology Works(CT11D-1006)
文摘Objective: To observe the electrocardiogram (ECG) and heart rate in a rabbit model ofhyperkalemia induced by potassium chloride, and provide theoretical and experimental reference for timely diagnosis of hyperkalemia clinically. Methods: Forty rabbits were randomly assigned into four groups. 0.9% isotonic saline solution was perfused in the group I , while 1.0%, 4.0% and 10.0% potassium chloride solutions were perfused in the other groups, respectively, to induce hyperkalemia. Results: The changes of serum potassium, ECG and heart rate before perfusion were significantly (P〈 0.05) different from those after perfusion in the other groups compared with group I . The effect of ECG variability rates was well consistent (Kappa = 0.724, P〈0.01) with that of serum potassium on diagnostic tests in the other groups. The area under ROC curve in diagnosis effect of ECG variability rates and sermn potassium on hyperkalaemia was much significantly larger (P〈0.01 and P〈0.05) compared with 0.5. There was asignificantly positive correlation between ECG variability rates and serum potassium (r= 0.865, P〈0.05 for bilateral Pearson test). There was certain positive correlation between heart rate and serum potassium, but the correlation was poor (r= 0.526, R2=0.277). Conclusion: A combination of serum potassium, ECG variability rates and heart rate should be considered and analyzed by synthesis to establish an accurate and timely diagnosis for hyperkalemia.
基金supported by the project VSHMOD-2009 ANR-09-BLAN-0104-01
文摘We study the geometry and the period map of nodal complex prime Fano threefolds with index 1 and degree 10.We show that these threefolds are birationally isomorphic to Verra threefolds,i.e.,hypersurfaces of bidegree (2,2) in P2 × P2.Using Verra's results on the period map for these threefolds and on the Prym map for double tale covers of plane sextic curves,we prove that the fiber of the period map for our nodal threefolds is the union of two disjoint surfaces,for which we give several descriptions.This result is the analog in the nodal case of a result of Debarre O,Iliev A,Manivel L (arXiv:0812.3670) in the smooth case.