Purpose: To examine the relationship between stenosis of the internal carotid artery (ICA) and pulsatile ocular blood flow (POBF). Methods: In 57 eyes of 30 patients who were referred for doppler ultrasound examinatio...Purpose: To examine the relationship between stenosis of the internal carotid artery (ICA) and pulsatile ocular blood flow (POBF). Methods: In 57 eyes of 30 patients who were referred for doppler ultrasound examination of the ICA we measured POBF and analyzed the correlation with degree of ipsilat-eral ICA stenosis. Results: There was a significant negative correlation between POBF and ipsilateral ICA stenosis (Pearson correlation coefficient, r =-0.516, P< 0.0001). In 14展开更多
Purpose: To compare the effect of bimatoprost, latanoprost, travoprost and unoprostone on intraocular pressure and on ocular blood flow. Methods: A 3 month prospective randomized study with 92 patients with primary op...Purpose: To compare the effect of bimatoprost, latanoprost, travoprost and unoprostone on intraocular pressure and on ocular blood flow. Methods: A 3 month prospective randomized study with 92 patients with primary open angle glaucoma or ocular hypertension without previous treatment for glaucoma or intraocular surgery. Intraocular pressure (IOP) pulse volume (PV)展开更多
Purpose: To assess if injured eyes develop ocular blood flow disturbances that may contribute to development of traumatic glaucoma. Materials and Methods: 25 patients hospitalized for eye injury and elevated IOP were ...Purpose: To assess if injured eyes develop ocular blood flow disturbances that may contribute to development of traumatic glaucoma. Materials and Methods: 25 patients hospitalized for eye injury and elevated IOP were evaluated 24 months after the trauma. All injured and fellow eyes underwent IOP measure, visual field (HFAII, Central 30/2SITA), pulsatile ocular blood flow analysis (POBF, OBF Labs UK), CDI examination (PSV, EDV, and RI) of Ophthalmic Artery, Central Retinal Artery, Short Posterior Ciliary Arteries. Results: IOP was significantly higher in injured eyes (15.1 vs 13.0±2.7mmHg) (P= 0,01), but only 2 eyes (8.8%) were under medical treatment POBF values were significantly lower in injured eyes: 11,25 μl/s in traumatised eyes and 15,40 μl/s in fellow eyes (P = 0.002). Resistivity Index (RI) of all investigated retrobulbar vessels was very significantly higher in injured eyes than in fellow eyes (P= 0.0001). There is no significant correlation between IOP and ocular blood flow disturbances.展开更多
The term 'Glaucoma' includes a wide range of diseases. Although it is widely accepted that elevated intraocular pressure (IOP) is an important risk factor in glaucoma, local and systemic vascular alterations h...The term 'Glaucoma' includes a wide range of diseases. Although it is widely accepted that elevated intraocular pressure (IOP) is an important risk factor in glaucoma, local and systemic vascular alterations have been implicated in the development of glaucomatous damage. Dorzolamide is a Carbonic An-hydrase Inhibitor (CAI), the vasodilatory characteristics of展开更多
Background: Systemic high dose application of magnesium leads to relaxation of vasospasm in small vessels. In normal pressure glaucoma patients vasospasm might be one of the major patho-genetic factors. Some investiga...Background: Systemic high dose application of magnesium leads to relaxation of vasospasm in small vessels. In normal pressure glaucoma patients vasospasm might be one of the major patho-genetic factors. Some investigations report on a neuroprotective action of oral magnesium. Aim of the present study was to examine the effect of oral magnesium on ocular blood flow and展开更多
Purpose: The aim of the study is to evaluate the influence of different betablockers on ocular hemodynamics and optic nerve head blood flow in glaucoma patients. Methods: 30 patients (12 male, 18 female) with primary ...Purpose: The aim of the study is to evaluate the influence of different betablockers on ocular hemodynamics and optic nerve head blood flow in glaucoma patients. Methods: 30 patients (12 male, 18 female) with primary open-angle glaucoma between 39 and 74 years of age were treated for 4 weeks each with betax-olol (BX), metipranolol 0.3% (ML) and timolol 0.5% (TL) in a randomized, double masked, crossover design. At baseline in-展开更多
Background: To investigate the effects of oral nimodipine on ocular hemodynamic parameters and color contrast sensitivity in patients with normal tension glaucoma (NTG). Methods: The study was performed in 14 consecut...Background: To investigate the effects of oral nimodipine on ocular hemodynamic parameters and color contrast sensitivity in patients with normal tension glaucoma (NTG). Methods: The study was performed in 14 consecutive NTG patients in a randomized placebo controlled double-masked cross-over design. The effects or oral nimodipine (60 mg) or placebo on ocular and systemic hemodynamic parameters and color contrast展开更多
To determine the pulse amplitude, ocular puslatile blood flow and perfusion pressure, we use the OBF pneumotonometer in healthy individuals and in patients with open angle glaucoma. Once determine the results compare ...To determine the pulse amplitude, ocular puslatile blood flow and perfusion pressure, we use the OBF pneumotonometer in healthy individuals and in patients with open angle glaucoma. Once determine the results compare it and show the experience in mexicans. The hypothesis is that the healthy individuals have higher pulse amplitud, pulsatile ocular blood flow and展开更多
We determine the pulse amplitud and pulsatil ocular blood flow in 111 healthy eyes and in 201 glaucoma eyes, using the Lang-ham Ocular Blood Flow System. We compared the values between gender, observig that women show...We determine the pulse amplitud and pulsatil ocular blood flow in 111 healthy eyes and in 201 glaucoma eyes, using the Lang-ham Ocular Blood Flow System. We compared the values between gender, observig that women showed higher POBF a PA than men in healthy eyes and in POAG. Healthy eyes: Male 27.9%; Female 72.1%. POAG eyes: Male 28.9%; Female 71.1%.展开更多
文摘Purpose: To examine the relationship between stenosis of the internal carotid artery (ICA) and pulsatile ocular blood flow (POBF). Methods: In 57 eyes of 30 patients who were referred for doppler ultrasound examination of the ICA we measured POBF and analyzed the correlation with degree of ipsilat-eral ICA stenosis. Results: There was a significant negative correlation between POBF and ipsilateral ICA stenosis (Pearson correlation coefficient, r =-0.516, P< 0.0001). In 14
文摘Purpose: To compare the effect of bimatoprost, latanoprost, travoprost and unoprostone on intraocular pressure and on ocular blood flow. Methods: A 3 month prospective randomized study with 92 patients with primary open angle glaucoma or ocular hypertension without previous treatment for glaucoma or intraocular surgery. Intraocular pressure (IOP) pulse volume (PV)
文摘Purpose: To assess if injured eyes develop ocular blood flow disturbances that may contribute to development of traumatic glaucoma. Materials and Methods: 25 patients hospitalized for eye injury and elevated IOP were evaluated 24 months after the trauma. All injured and fellow eyes underwent IOP measure, visual field (HFAII, Central 30/2SITA), pulsatile ocular blood flow analysis (POBF, OBF Labs UK), CDI examination (PSV, EDV, and RI) of Ophthalmic Artery, Central Retinal Artery, Short Posterior Ciliary Arteries. Results: IOP was significantly higher in injured eyes (15.1 vs 13.0±2.7mmHg) (P= 0,01), but only 2 eyes (8.8%) were under medical treatment POBF values were significantly lower in injured eyes: 11,25 μl/s in traumatised eyes and 15,40 μl/s in fellow eyes (P = 0.002). Resistivity Index (RI) of all investigated retrobulbar vessels was very significantly higher in injured eyes than in fellow eyes (P= 0.0001). There is no significant correlation between IOP and ocular blood flow disturbances.
文摘The term 'Glaucoma' includes a wide range of diseases. Although it is widely accepted that elevated intraocular pressure (IOP) is an important risk factor in glaucoma, local and systemic vascular alterations have been implicated in the development of glaucomatous damage. Dorzolamide is a Carbonic An-hydrase Inhibitor (CAI), the vasodilatory characteristics of
文摘Background: Systemic high dose application of magnesium leads to relaxation of vasospasm in small vessels. In normal pressure glaucoma patients vasospasm might be one of the major patho-genetic factors. Some investigations report on a neuroprotective action of oral magnesium. Aim of the present study was to examine the effect of oral magnesium on ocular blood flow and
文摘Purpose: The aim of the study is to evaluate the influence of different betablockers on ocular hemodynamics and optic nerve head blood flow in glaucoma patients. Methods: 30 patients (12 male, 18 female) with primary open-angle glaucoma between 39 and 74 years of age were treated for 4 weeks each with betax-olol (BX), metipranolol 0.3% (ML) and timolol 0.5% (TL) in a randomized, double masked, crossover design. At baseline in-
文摘Background: To investigate the effects of oral nimodipine on ocular hemodynamic parameters and color contrast sensitivity in patients with normal tension glaucoma (NTG). Methods: The study was performed in 14 consecutive NTG patients in a randomized placebo controlled double-masked cross-over design. The effects or oral nimodipine (60 mg) or placebo on ocular and systemic hemodynamic parameters and color contrast
文摘To determine the pulse amplitude, ocular puslatile blood flow and perfusion pressure, we use the OBF pneumotonometer in healthy individuals and in patients with open angle glaucoma. Once determine the results compare it and show the experience in mexicans. The hypothesis is that the healthy individuals have higher pulse amplitud, pulsatile ocular blood flow and
文摘We determine the pulse amplitud and pulsatil ocular blood flow in 111 healthy eyes and in 201 glaucoma eyes, using the Lang-ham Ocular Blood Flow System. We compared the values between gender, observig that women showed higher POBF a PA than men in healthy eyes and in POAG. Healthy eyes: Male 27.9%; Female 72.1%. POAG eyes: Male 28.9%; Female 71.1%.
