Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A50- year- old patient suddenly presented with an isolated palsy of the right lateral rect...Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A50- year- old patient suddenly presented with an isolated palsy of the right lateral rectus muscle which recovered in 3 weeks after a short- lasting corticosteroid therapy but relapsed. Cerebral and orbital imaging were normal. Orbital pain with a fluctuating course occurred 6 months later. Two years after the clinical onset, orbital CT scan revealed a fusiform hypertrophy of the right lateral rectus muscle which was enhanced by contrast. After corticosteroid treatment, the symptoms improved and CT scan became normal. Conclusion. Orbital myositis may not be ruled out in case of painless ophthalmoplegia and systematic and repeated imaging is necessary.展开更多
Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A 50-year-old patient suddenl y presented with an isolated palsy of the right lateral rect...Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A 50-year-old patient suddenl y presented with an isolated palsy of the right lateral rectus muscle which reco vered in 3 weeks after a short-lasting corticosteroid therapy but relapsed. Cer ebral and orbital imaging were normal. Orbital pain with a fluctuating course oc curred 6 months later. Two years after the clinical onset, orbital CT scan revea led a fusiform hypertrophy of the right lateral rectus muscle which was enhanced by contrast.After corticosteroid treatment, the symptoms improved and CT scan b ecame normal. Conclusion. Orbital myositis may not be ruled out in case of painl ess ophthalmoplegia and systematic and repeated imaging is necessary.展开更多
To report results of treatment with a monoclonal antibody (infliximab) directe d against tumor necrosis factor α.in seven patients with chronic and difficult -to-control idiopathic orbital inflammation (orbital myosi...To report results of treatment with a monoclonal antibody (infliximab) directe d against tumor necrosis factor α.in seven patients with chronic and difficult -to-control idiopathic orbital inflammation (orbital myositis). Observational case series. Retrospective data were collected from seven patients who had idiop athic orbital inflammation and who were evaluated at three medical centers. All patients were treated with infliximab after the failure of traditional therapy, which included corticosteroids, radiotherapy, or anti-inflammatory chemotherape utic agents. All seven patients had a favorable response to treatment with infli ximab. One patient with Behc.et disease required supplemental oral corticosteroi ds. Pain, swelling, and need for concomitant corticosteroids were the primary me asures of treatment success. Symptoms of comorbid disease in four patients also improved (Crohn disease in two, Behcet disease in one, and psoriasis in one). Th ere were no untoward effects of treatment after a mean follow-up of 15.7 months (range, 4 to 31 months). Treatment with infliximab appears to offer another th erapeutic option in cases of recalcitrant or recurrent idiopathic orbital inflam mation in which conventional treatment fails.展开更多
Introduction.Orbital myositis is an idiopathic inflammation of the extraoccular muscles.It is often included under the broad description of orbital pseudotumor.It is commonly a unilateral affection.Case report.We repo...Introduction.Orbital myositis is an idiopathic inflammation of the extraoccular muscles.It is often included under the broad description of orbital pseudotumor.It is commonly a unilateral affection.Case report.We report one case of bilateral orbital myositis in a 45-year-old woman.The first symptoms were diplopia and acute bilateral orbital pain exacerbated by eye movements.Physical examination especially neurological was normal.Serum creatine kinase and biological thyroid function were normal.CT scan found a bilateral enlargement of rectus oculi medialis and lateralis.Clinical improvement was obtained a few days after oral corticosteroid treatment with remission of all signs.Conclusion.Orbital myositis is a rare entity.90-95p.cent of cases are unilateral.Bilateral forms are exceptional and in this case require search for specific etiologies particularly thyroid ophthalmopathy.There is controversy concerning treatment options but corticosteroids are still the most common first choice therapy with good outcome.展开更多
文摘Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A50- year- old patient suddenly presented with an isolated palsy of the right lateral rectus muscle which recovered in 3 weeks after a short- lasting corticosteroid therapy but relapsed. Cerebral and orbital imaging were normal. Orbital pain with a fluctuating course occurred 6 months later. Two years after the clinical onset, orbital CT scan revealed a fusiform hypertrophy of the right lateral rectus muscle which was enhanced by contrast. After corticosteroid treatment, the symptoms improved and CT scan became normal. Conclusion. Orbital myositis may not be ruled out in case of painless ophthalmoplegia and systematic and repeated imaging is necessary.
文摘Introduction. We report a case of orbital myositis revealed by a relapsing and initally painless ophthalmoplegia. Case report. A 50-year-old patient suddenl y presented with an isolated palsy of the right lateral rectus muscle which reco vered in 3 weeks after a short-lasting corticosteroid therapy but relapsed. Cer ebral and orbital imaging were normal. Orbital pain with a fluctuating course oc curred 6 months later. Two years after the clinical onset, orbital CT scan revea led a fusiform hypertrophy of the right lateral rectus muscle which was enhanced by contrast.After corticosteroid treatment, the symptoms improved and CT scan b ecame normal. Conclusion. Orbital myositis may not be ruled out in case of painl ess ophthalmoplegia and systematic and repeated imaging is necessary.
文摘To report results of treatment with a monoclonal antibody (infliximab) directe d against tumor necrosis factor α.in seven patients with chronic and difficult -to-control idiopathic orbital inflammation (orbital myositis). Observational case series. Retrospective data were collected from seven patients who had idiop athic orbital inflammation and who were evaluated at three medical centers. All patients were treated with infliximab after the failure of traditional therapy, which included corticosteroids, radiotherapy, or anti-inflammatory chemotherape utic agents. All seven patients had a favorable response to treatment with infli ximab. One patient with Behc.et disease required supplemental oral corticosteroi ds. Pain, swelling, and need for concomitant corticosteroids were the primary me asures of treatment success. Symptoms of comorbid disease in four patients also improved (Crohn disease in two, Behcet disease in one, and psoriasis in one). Th ere were no untoward effects of treatment after a mean follow-up of 15.7 months (range, 4 to 31 months). Treatment with infliximab appears to offer another th erapeutic option in cases of recalcitrant or recurrent idiopathic orbital inflam mation in which conventional treatment fails.
文摘Introduction.Orbital myositis is an idiopathic inflammation of the extraoccular muscles.It is often included under the broad description of orbital pseudotumor.It is commonly a unilateral affection.Case report.We report one case of bilateral orbital myositis in a 45-year-old woman.The first symptoms were diplopia and acute bilateral orbital pain exacerbated by eye movements.Physical examination especially neurological was normal.Serum creatine kinase and biological thyroid function were normal.CT scan found a bilateral enlargement of rectus oculi medialis and lateralis.Clinical improvement was obtained a few days after oral corticosteroid treatment with remission of all signs.Conclusion.Orbital myositis is a rare entity.90-95p.cent of cases are unilateral.Bilateral forms are exceptional and in this case require search for specific etiologies particularly thyroid ophthalmopathy.There is controversy concerning treatment options but corticosteroids are still the most common first choice therapy with good outcome.
